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2000 articles

November 202624

Case ReportPediatrics

False-Positive Prenatal Suspicion of Partial Anomalous Pulmonary Venous Connection: A Benign Confluence Variant Clarified by Cardiac CT.

Prenatal ultrasound raised suspicion of partial anomalous pulmonary venous connection (PAPVC). After birth, echocardiography—limited by acoustic windows and influenced by the prenatal interpretation—also suggested…

EchocardiographyNov 1, 2026Read case
Case ReportOphthalmology

Klebsiella pneumoniae Endogenous Endophthalmitis in an Active Duty Service Member.

A healthy, immunocompetent 47-year-old active-duty man developed fever, chills, and fatigue, tested positive for COVID, and then experienced painful right-eye vision loss with a temporal field deficit.

Mil MedNov 1, 2026Read case
Case ReportPediatrics

An Adolescent With Neurosyphilis.

A previously healthy 17-year-old boy developed two weeks of myoclonus affecting his right thumb and middle finger, followed by focal seizures in the right arm that generalized.

PediatricsNov 1, 2026Read case
Case ReportGeneral Surgery

Surgical Treatment of Hepatic Fascioliasis in Two Civilian Employees of the Armed Forces of Ukraine: A Case Report.

Two civilian employees of the Armed Forces of Ukraine presented with hepatic lesions and symptoms including right upper quadrant pain, nausea, vomiting, back pain, or transient jaundice.

Mil MedNov 1, 2026Read case
Clinical ResearchEndocrinology

Effects of Multicomponent Training on Body Composition and Cardiorespiratory Fitness in Adults With Type 2 Diabetes: A Randomized Controlled Trial.

This randomized controlled trial assessed 14 weeks of small-sided soccer training in adults aged 40–70 years with type 2 diabetes.

Scand J Med Sci SportsNov 1, 2026Read summary
Case ReportInfectious Diseases

Mycobacterium abscessus bacteremia: A narrative literature review based on a case report.

The report describes a catheter-associated bloodstream infection caused by Mycobacterium abscessus subsp. massiliense. The authors also reviewed published M.

Enferm Infecc Microbiol Clin (Engl Ed)Nov 1, 2026Read case
Case ReportPediatrics

Domino Liver Transplantation Using the Explanted Native Liver of a Multivisceral Transplant Recipient: A Pediatric Case Report and Systematic Review.

A 4-month-old boy underwent multivisceral transplantation after near-total enterectomy complicated by gastric, duodenal, and bladder fistulas.

Pediatr TransplantNov 1, 2026Read case
Clinical ResearchEmergency MedicineOpen access

Pain-Related Outcome Domains and Measures in Randomized Controlled Trials of Treatment for Acute Abdominal Pain: A Systematic Review.

This PRISMA-guided systematic review mapped pain-related outcome domains and measures in randomized controlled trials of acute abdominal pain treatment.

Eur J PainNov 1, 2026Read summary
Clinical ResearchPulmonologyOpen access

PURE PRIME: implementing Pulmonary Rehabilitation in Primary care - a randomized-controlled feasibility trial.

PURE PRIME was a randomized controlled feasibility trial testing pulmonary rehabilitation (PR) in private physiotherapy or exercise physiology practices for people with chronic respiratory disease.

Ann Am Thorac SocNov 1, 2026Read summary
Clinical ResearchOphthalmology

First-in-Human Regulatory T Cell-Derived Exosomes Plus Ranibizumab for Refractory nAMD.

This single-centre, prospective, open-label phase 1a dose-escalation trial evaluated the safety and maximum tolerated dose of intravitreal autologous regulatory T cell-derived exosomes (TregExo) coformulated with…

J Extracell VesiclesNov 1, 2026Read summary
Case ReportNeurology

Polyneuropathy, Organomegaly, Endocrinopathy, M-Protein, and Skin Changes (POEMS) Syndrome With Characteristic Muscle Biopsy Findings and Without M-Protein.

A 63-year-old woman referred with presumed CIDP had not responded to IVIG or steroids. Her presentation included marked weight loss, papilledema, skin changes, thrombocytosis, thromboembolisms, hemi-diaphragmatic…

NeurologistNov 1, 2026Read case
Clinical ResearchEndocrinology

Effectiveness of Traditional Chinese Fitness Methods on Depressive Symptoms and Glycaemic Control in Patients With Type 2 Diabetes and Comorbid Depression: A Systematic Review and Meta-Analysis of Taijiquan and Baduanjin.

This systematic review and meta-analysis assessed randomised controlled trials of Taijiquan and Baduanjin in people with type 2 diabetes and comorbid depression. Eight trials, all conducted in China, were included.

Endocrinol Diabetes MetabNov 1, 2026Read summary
Clinical ResearchHematology

Genotypic-Phenotypic Correlations in Non-HbE β-Thalassemia Intermedia: A Geographic Systematic Review.

This PRISMA-guided systematic review qualitatively synthesized 21 studies of genotype–phenotype correlations in non-HbE β-thalassemia intermedia, a heterogeneous disorder now included within non-transfusion-dependent…

Mol Genet Genomic MedNov 1, 2026Read summary
Clinical ResearchDermatology

INDIVIDUAL ARTICLE: Randomized Double-Blind, Placebo-Controlled Study of a Supplement and Serum on Grey Hair.

This randomized, double-blind, placebo-controlled study assessed a topical serum and oral supplement, alone and in combination, in 173 men and women aged 28–65 years with 5–25% grey hair.

J Drugs DermatolNov 1, 2026Read summary
Clinical ResearchPathology (Anatomic & Clinical)

Salivary biomarkers in periodontal diseases: A systematic review.

This systematic review assessed salivary biomarkers for diagnosing and monitoring periodontitis in systemically healthy people. It included 11 human studies with cross-sectional or interventional designs.

J Am Dent AssocNov 1, 2026Read summary
Clinical ResearchGeriatrics

Evaluating the accuracy of brief cognitive assessments for the early detection of cognitive impairment in adults across primary and specialty care settings: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed brief, freely available cognitive tests for detecting cognitive impairment, including mild cognitive impairment and dementia, in adults aged 55 years and older in…

Alzheimers DementNov 1, 2026Read summary
Clinical ResearchDermatology

Clindamycin and bacterial load reduction as prophylaxis for surgical site infection after below-knee flap and graft procedures.

This randomised controlled trial evaluated clindamycin prophylaxis and preoperative chlorhexidine washing in consecutive patients undergoing below-knee flap or graft procedures.

Aust J Gen PractNov 1, 2026Read summary
Case ReportOncology (Medical)Open access

Pembrolizumab Activity in Tyrosine Kinase Inhibitor-Refractory Metastatic GIST: A Case Report.

A man with epithelioid small-bowel GIST developed liver metastases seven years after diagnosis. The tumor carried a primary KIT exon 11 D579del mutation, a secondary KIT exon 17 D820G mutation, and CDKN2A/CDKN2B…

Cancer Rep (Hoboken)Nov 1, 2026Read case
Clinical ResearchGastroenterology

Clinical significance of isolated periappendiceal red patch in ulcerative colitis: A systematic review, meta-analysis, and meta-regression.

This systematic review and meta-analysis examined whether an isolated periappendiceal red patch (PARP) is associated with disease extent or outcomes in ulcerative colitis.

Inflamm Bowel DisNov 1, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Biologics and small molecules for perianal Crohn's disease: a systematic review and meta-analyses of randomized placebo-controlled trials.

This systematic review and meta-analysis pooled placebo-controlled randomized trials of advanced therapies for perianal fistulizing Crohn’s disease.

Inflamm Bowel DisNov 1, 2026Read summary
Clinical ResearchGeriatrics

Systematic Review of Smart Home Assistive Technology Devices for Supporting People With Dementia Living in Their Homes.

This systematic review and meta-analysis assessed smart home and wearable assistive technologies for people with dementia living at home or in supported accommodation.

Int J Geriatr PsychiatryNov 1, 2026Read summary
Clinical ResearchGeriatrics

Exercise and Nutritional Interventions for Muscle Strength, Physical Performance, and Body Composition Among Older Adults With Sarcopenia or Pre-Sarcopenia: A Network Meta-Analysis.

This network meta-analysis compared exercise, nutritional, and combined interventions with control strategies in older adults with sarcopenia or pre-sarcopenia.

Geriatr Gerontol IntNov 1, 2026Read summary
Clinical ResearchOncology (Medical)

Liposomal irinotecan and capecitabine plus bevacizumab as second-line therapy in metastatic colorectal cancer: A multicenter, single-arm study.

This multicenter, single-arm clinical study evaluated liposomal irinotecan, capecitabine, and bevacizumab as second-line therapy in patients with metastatic colorectal cancer progressing after oxaliplatin-based…

CancerNov 1, 2026Read summary
Case ReportOncology (Medical)Open access

Preoperative Temporal Elevation of Cytokeratin 19 Fragment in Thymoma With Extensive Necrosis: A Case Report.

A 73-year-old man presented with chest pain, and CT showed a mediastinal mass with pleural effusion. White blood cell count, C-reactive protein, and cytokeratin 19 fragment (CYFRA) were elevated; CYFRA was 61.3 ng/mL.

Thorac CancerNov 1, 2026Read case

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