AI-curated PubMed digests

Your Weekly Medical Digest, Strictly Latest Publications.

Never miss a practice-changing paper again. Stay informed, stay relevant, and lead the conversation with AI-powered literature reviews.

Start for freeHow it works

Start free · No credit card required

  • Audio + text
  • Clinical research
  • Expert curated
  • Open access
Digest for Sep 6, 2026 – Sep 12, 2026
12 papersUpdated recently
Clinical ResearchClinical ResearchOpen access

Osimertinib With or Without Chemotherapy in Advanced Non-Small Cell Lung Cancer With EGFR and Concurrent TP53 Mutations: A Randomized Clinical Trial.

JAMASep 8, 2026

This phase 3 randomized clinical trial evaluated the efficacy and safety of osimertinib combined with chemotherapy versus osimertinib alone in 294 patients with advanced non-small cell lung cancer (NSCLC) harboring…

Key findings

  • Median progression-free survival was 34.0 months for osimertinib plus chemotherapy versus 15.6 months for osimertinib alone.
  • The hazard ratio for progression-free survival was 0.44, indicating a significant benefit for combination therapy.
  • The incidence of grade 3 or higher treatment-related adverse events was higher in the combination group.
Specialty: Oncology (Medical)View full text
Live · Publications from PubMed counted over the past 7 days

Why xxcode

Less searching. More knowing.

Everything below happens automatically, every week, tuned to how you practice.

Only the last 7 days

Strictly fresh literature—never stale archives or repeats.

Evidence-ranked

Trials, meta-analyses and systematic reviews surface first.

Read or listen

A scannable brief or a short audio episode for your commute.

Tuned to your field

Pick your specialties once—every digest follows your focus.

How it works

From preferences to digest, without the busywork

xxcode keeps you current without adding hours to your week—three straightforward beats, no jargon.

  1. 01

    Tell us how you practice

    Choose your specialty and interests, and how long you usually have to listen or read—like the length of a commute or a coffee break.

  2. 02

    We gather what is new and important

    Behind the scenes we watch the latest research in your areas and prioritize papers that are likely to matter for patient care and day-to-day practice.

  3. 03

    You get a digest you can use right away

    You receive a weekly summary that is easy to scan. Depending on your plan, you can read the full brief or listen to it like a short show—whenever it fits your day.

Trending Now

See what clinicians are reading

A public preview of recent literature — no account required. Open any article, then create your personalized digest when you are ready.

View all Trending
AllClinical ResearchCase Reports
FeaturedClinical ResearchOncology (Medical)

Osimertinib With or Without Chemotherapy in Advanced Non-Small Cell Lung Cancer With EGFR and Concurrent TP53 Mutations: A Randomized Clinical Trial.

JAMASep 8, 2026Open access

This phase 3 randomized clinical trial evaluated the efficacy and safety of osimertinib combined with chemotherapy versus osimertinib alone in 294 patients with advanced non-small cell lung cancer (NSCLC) harboring…

Why it matters

The findings suggest that combining osimertinib with chemotherapy may enhance treatment outcomes for patients with specific genetic mutations in advanced NSCLC, potentially guiding personalized treatment strategies.

Read summary
Clinical ResearchHematology

Azacitidine-Venetoclax or Induction Chemotherapy for Acute Myeloid Leukemia.

This phase 2 randomized trial compared azacitidine plus venetoclax to induction chemotherapy in 172 previously untreated adults with acute myeloid leukemia (AML) eligible for induction.

N Engl J MedSep 3, 2026Read summary
Clinical ResearchPsychiatry

The efficacy of modified psychodynamic psychotherapy for patients with schizophrenia-spectrum disorders in Germany: a prospective, single-centre, assessor-blinded, parallel-group, randomised controlled trial.

This randomized controlled trial evaluated the efficacy of Modified Psychodynamic Psychotherapy for Schizophrenia (MPP-S) combined with treatment as usual (TAU) in 130 outpatients with schizophrenia-spectrum disorders…

Lancet PsychiatrySep 10, 2026Read summary
Clinical ResearchGeriatrics

Effect of exercise on bone health in middle aged and older adults: hierarchical network meta-analysis of randomised trials.

This hierarchical network meta-analysis evaluated the impact of various exercise types on bone mineral density (BMD) and fracture risk in adults aged 40 and older.

BMJSep 9, 2026Read summary
Clinical ResearchNephrology

Effect of intradialytic exercise on cardiovascular structural and functional parameters in maintenance haemodialysis: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effects of intradialytic exercise (IDE) on cardiovascular parameters in patients undergoing maintenance haemodialysis (MHD).

BMJ OpenSep 9, 2026Read summary
View all TrendingCreate your personalized digest
Learning that Gives Back.

Learning that Gives Back.

At xxcode, we believe learning can create impact beyond medicine. We are committed to directing a portion of future subscription revenue toward helping homeless animals with food, veterinary care, medications, and other essential needs. Until subscription revenue begins, selected initiatives may be funded directly by the xxcode team. Follow our Impact page to see the work, stories, and support made possible along the way.

See our impact →

Stay current in minutes, not hours.

Your personalized weekly digest, delivered and ready every week.

Start for free