An Adolescent With Neurosyphilis.

PediatricsNov 1, 2026
Case ReportPediatricsInfectious DiseasesNeurology

Danielle Owerko, Alina Burek, Jennifer Watson

✦ AI-curated · Sources linked

Case in brief

A previously healthy 17-year-old boy developed two weeks of myoclonus affecting his right thumb and middle finger, followed by focal seizures in the right arm that generalized. A confidential psychosocial history established that he was sexually active, prompting STI screening. A reactive rapid plasma reagin test and confirmatory treponemal testing of cerebrospinal fluid established neurosyphilis.

What made this case unusual

The presentation was focal myoclonus and seizures in an adolescent, with the diagnosis prompted by confidential sexual history and confirmed through cerebrospinal fluid testing.

Diagnostic / clinical pearl

Consider neurosyphilis when an adolescent with sexual exposure has unexplained neurologic symptoms; confidential, comprehensive history-taking can guide appropriate STI testing.

Source

PubMed · PMID 42869444

Published in Pediatrics. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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