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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

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FeaturedClinical ResearchPediatrics

RSV Bivalent Prefusion F Protein Vaccine in Pregnancy and Protection Against RSV-Associated Illness in Infants: A Systematic Review and Meta-Analysis.

JAMA PediatrNov 1, 2026

This systematic review and meta-analysis assessed real-world effectiveness of maternal RSV bivalent prefusion F protein vaccination in preventing RSV-associated lower respiratory tract infection (LRTI) hospitalization…

Why it matters

RSV-associated LRTI hospitalization is an important early-life outcome, and these real-world findings indicate that maternal RSVpreF vaccination is associated with substantial protection across the first 6 months.

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Also worth knowing

Clinical ResearchNephrologyOpen access

Transplantation of Hepatitis B Surface Antigen Positive or Viremic Kidneys: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed outcomes after transplantation of hepatitis B surface antigen-positive or viremic kidneys into non-viremic kidney transplant recipients.

Clin TransplantNov 1, 2026Read summary
Clinical ResearchInfectious Diseases

Extended in vivo activity of VRC01 HIV-1 prophylaxis entails initial protective efficacy and subsequent breakthrough infections.

The two parallel randomized antibody-mediated prevention trials assessed whether intravenous VRC01 prevented HIV-1 acquisition, with this analysis extending follow-up through the week 104 final visit.

Sci Transl MedNov 4, 2026Read summary
Clinical ResearchInfectious Diseases

Efficacy of artemisinin derivatives and kelch13 mutations in Plasmodium falciparum: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed ACT efficacy and the distribution of pfk13 mutations in studies of uncomplicated Plasmodium falciparum malaria across Asia, Africa, and the Americas.

Trans R Soc Trop Med HygNov 3, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Epidemiological, etiological, and antifungal resistance patterns of vulvovaginal Candida spp. infections in Cameroon: A systematic review and meta-analysis.

This systematic review and meta-analysis pooled evidence from 34 studies of vulvovaginal Candida infection and vulvovaginal candidiasis (VVC) in Cameroon.

Med MycolNov 3, 2026Read summary
Clinical ResearchNephrology

Association of Helicobacter pylori eradication with proteinuria reduction and kidney outcomes: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed whether Helicobacter pylori eradication is associated with renal benefits in people with kidney disease or proteinuria.

J NephrolOct 30, 2026Read summary
Clinical ResearchInfectious Diseases

Predictors of chronic arthralgia after chikungunya virus infection: a systematic review and meta-analysis.

This systematic review and meta-analysis examined predictors of chronic arthralgia, defined as lasting at least 3 months, after laboratory-confirmed chikungunya infection.

J Travel MedOct 30, 2026Read summary
Clinical ResearchInfectious Diseases

Endpoint-specific mortality associated with malignancy among adults with sepsis or septic shock: a systematic review and meta-analysis.

This systematic review and meta-analysis examined mortality among adults with sepsis or septic shock, comparing patients with and without malignancy.

Ann MedOct 30, 2026Read summary
Clinical ResearchInfectious Diseases

Risk factors for Post-COVID-19 Syndrome in patients hospitalized for severe acute respiratory syndrome: systematic review and meta-analysis.

This systematic review and meta-analysis examined factors associated with post-COVID-19 syndrome among patients discharged after hospitalization for severe acute respiratory syndrome.

Cien Saude ColetOct 30, 2026Read summary
Clinical ResearchInfectious Diseases

The Safety, Pharmacokinetics, and Antiviral Activity of ABI-4334, A Novel Next-Generation Hepatitis B Capsid Assembly Modulator.

Two randomized Phase 1 studies assessed ABI-4334, a hepatitis B capsid assembly modulator, in healthy volunteers and participants with chronic hepatitis B (cHBV).

J Viral HepatNov 11, 2026Read summary
Clinical ResearchNeurologyOpen access

Immune checkpoints inhibitors in the treatment of progressive multifocal leukoencephalopathy: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed immune checkpoint inhibitors (ICIs) for progressive multifocal leukoencephalopathy (PML), pooling reports involving 186 patients from 52 articles.

Neurol SciNov 4, 2026Read summary
Clinical ResearchEndocrinology

Severe Infection Outcomes With SGLT2 Versus DPP-4 Inhibitors in Type 2 Diabetes: A Systematic Review and Active-Comparator Meta-Analysis of Real-World Cohorts.

This systematic review and active-comparator meta-analysis examined real-world severe infection outcomes among people with type 2 diabetes treated with SGLT2 inhibitors versus DPP-4 inhibitors.

Endocrinol Diabetes MetabNov 1, 2026Read summary

Showing 12 of 63 publications that cleared our clinical screen in the last 14 days.

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