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2000 articles
November 202624
Effects of nutrition counseling on quality of life in adults with cancer: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed randomized controlled trials of nutrition counseling and quality of life (QoL) in adults with cancer.
Progression-Associated Loss of SMARCB1/INI1 Expression in Mismatch Repair-Deficient Glioblastoma.
A patient with mismatch repair-deficient glioblastoma had a recurrent tumor in which testing identified a second SMARCB1 mutation and complete loss of SMARCB1/INI1 protein expression.
Esketamine-Based Versus Sevoflurane-Based Anesthesia with Dexmedetomidine for Emergence Agitation in Pediatric Corneal Suture Removal: A Randomised Controlled Trial.
Corneal suture removal, particularly microsurgery requiring complete immobility, demands adequate anesthetic depth while ensuring rapid recovery.
Identification of AKAP6 as a candidate gene for charcot-marie-tooth disease: expanding the clinical and molecular spectrum.
A family was evaluated for axonal sensorimotor polyneuropathy. Whole-exome sequencing, with copy-number variant detection and runs-of-homozygosity analysis, identified a homozygous nonsense variant in AKAP6, c.4774 C >…
An encephalitis-like syndrome in an adult with methylmalonic acidemia and hyperhomocysteinemia: A case report.
A 56-year-old man developed fever and slowed responses, followed by disorganized speech, visual hallucinations, impaired consciousness, and pyramidal signs.
Intestinal tuberculosis with multiple intestinal perforations in a 5-month-old infant: The role of metagenomic next-generation sequencing: a case report and literature review.
A 5-month-old boy presented with fever and abdominal distension that progressed to intestinal obstruction and multiple perforations involving the distal ileum and appendiceal region.
Mucus Plugging Across Multiple Chronic Respiratory Diseases: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis assessed mucus-plug prevalence, clinical characteristics and outcomes across chronic respiratory diseases, including asthma, COPD and cystic fibrosis.
Curriculum-Aligned Conversational AI to Support Pathology Self-Directed Learning in Preclinical Medical Students: Crossover Randomized Pilot Study.
This crossover randomized pilot study evaluated a curriculum-aligned custom GPT for self-directed pathology learning among 44 second-year medical students at the University of South Carolina, Floyd School of Medicine.
Development and evaluation of a subjective measurement of geographical hardness-to-reach: a survey of data collectors in a large-scale cluster randomised trial of azithromycin mass drug administration.
This sub-study within a large-scale cluster-randomised trial of azithromycin mass drug administration in Mali developed and evaluated a 14-item survey of village accessibility, completed by 25 data collectors.
Testing the EQ-HWB-9 with seven-day versus today recall periods in dementia: variability and recall adherence under health fluctuations.
This mixed-methods randomized study compared “7-day” and “today” EQ-HWB-9 recall periods in people living with dementia and caregiver dyads recruited from German primary care.
The relationship between sirtuin1 gene polymorphism and coronary heart disease: Systematic review and meta-analysis.
This systematic review and meta-analysis examined associations between four SIRT1 gene polymorphisms and coronary heart disease (CHD), drawing on 9 articles with 1,839 cases and 1,937 controls.
Effects of intradermal lymphocyte therapy in patients with recurrent pregnancy loss: secondary analysis of a randomized controlled trial investigating purinergic signaling, inflammation, and cellular energy status.
This secondary analysis of a randomized controlled trial examined low-dose intradermal lymphocyte therapy (ILT) in 100 patients with recurrent pregnancy loss (RPL), comparing 50 treated patients with 50 receiving…
Intra-arterial tenecteplase for acute basilar artery occlusion with sufficient recanalization after thrombectomy: the INSIST-IT randomized clinical trial.
The INSIST-IT multicentre, prospective, randomised trial assessed adjunctive intra-arterial tenecteplase after successful endovascular reperfusion in patients with acute basilar artery occlusion treated within 24 hours…
Peptides for male sexual dysfunction: a systematic review of emerging evidence.
This PRISMA-guided systematic review assessed human studies of peptide-based therapies for male sexual function, reproductive hormones, and semen parameters.
Optimal duration of levetiracetam prophylaxis following supratentorial tumor resection: a multi-study analysis.
This systematic review and meta-analysis compared short-course (≤ 9 days) with extended-course (> 9 days) levetiracetam prophylaxis in seizure-naïve patients after supratentorial tumor resection.
Subsequent epilepsy surgery after SEEG-guided radiofrequency thermocoagulation: Outcomes and prognostic value of treatment response-a systematic review and meta-analysis.
This systematic review and meta-analysis assessed outcomes after resective, disconnective, or ablative epilepsy surgery in patients previously treated with SEEG-guided radiofrequency thermocoagulation (SEEG-RFTC), and…
Efficacy of diadynamic currents versus transcutaneous electrical nerve stimulation for transcutaneous tibial nerve stimulation in subjects with overactive bladder syndrome: A double-blind randomized controlled trial.
This double-blind randomized controlled trial compared transcutaneous tibial nerve stimulation (TTNS) delivered with diadynamic currents (DDC) or transcutaneous electrical nerve stimulation (TENS) in women aged 18–80…
Angiotensin receptor neprilysin inhibitors and renal outcomes in patients with heart failure: a systematic review and meta-analysis.
This systematic review and meta-analysis examined renal outcomes with angiotensin receptor neprilysin inhibitors (ARNi) versus renin-angiotensin-aldosterone system inhibitors (RAASi) alone in patients with heart…
Discontinuation of renin-angiotensin system inhibitors before non-cardiac surgery: a meta-analysis.
This systematic review and meta-analysis of five randomized controlled trials compared discontinuation with continuation of renin-angiotensin system inhibitors before non-cardiac, non-vascular surgery.
Women's cardiovascular health in Aotearoa New Zealand: insights from a systematic literature review.
This systematic review synthesised research on women’s cardiovascular health in Aotearoa New Zealand, including clinical outcomes, awareness and lived experience.
Effects of a parenting and unconditional cash transfer intervention on child development and maternal well-being in urban Bangladesh: medium-term follow-up of a cluster randomised controlled trial.
This medium-term follow-up of a cluster randomised controlled trial in Rangpur, Bangladesh, compared parenting plus unconditional cash transfers with cash transfers alone.
Delayed pancytopenia following ingestion of wild mushrooms consistent with Hypholoma fasciculare: A case report.
A 57-year-old man presented with fever and generalized weakness about 10 days after eating self-collected wild mushrooms consistent with Hypholoma fasciculare. Testing showed delayed-onset pancytopenia.
Clinical characteristics, treatment, and prognosis of sexual-related rectal foreign bodies: a systematic review and meta-analysis.
This systematic review and meta-analysis examined clinical features, management, and outcomes of sexual-related rectal foreign bodies, drawing on 59 case reports, case series, and cohort studies from 22 countries, with…
Successful rechallenge with almonertinib and corticosteroids after gefitinib-induced interstitial lung disease: A case report and literature review.
A 53-year-old never-smoking woman with stage IV, EGFR L858R-mutant lung adenocarcinoma developed progressive dyspnea and hypoxemia after two months of gefitinib, despite an initial tumor response.
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