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643 articles
November 202624
Severe Atherogenic Dyslipidemia in Ataxia-Telangiectasia Despite Cachexia: Mechanistic Insights into Mitochondrial Dysfunction.
A 25-year-old woman with genetically confirmed ataxia-telangiectasia and extreme underweight (body mass index 12.5 kg/m²) developed severe mixed atherogenic dyslipidemia despite modest dietary fat intake and no…
Spinocerebellar Ataxia Type 6 Concurrent with Normal-Pressure Hydrocephalus: A Case Report.
A 73-year-old man with two years of progressive gait disturbance had gaze-evoked nystagmus, dysarthria, limb ataxia, a broad-based shuffling gait, and urinary urgency.
The Harvesting Oblique Tuberosity (HOT) Technique: A Simplified Clinical Approach for Standardized Connective Tissue Graft Retrieval.
This clinical report presents the harvesting oblique tuberosity (HOT) technique for retrieving autogenous connective tissue grafts from the maxillary tuberosity.
Pseudo-Metabolic Alkalosis: A Hidden Laboratory Pitfall With Elevated LDH.
A 33-year-old man presented with progressive exertional dyspnea, syncope, and paresthesia. Testing showed pancytopenia, macrocytosis, LDH >3600 U/L, low haptoglobin, and vitamin B₁₂ <68 pg/mL, consistent with pernicious…
Coexistence of ARNT::ALK and TPM3::ALK doublegene fusion in an ALK-rearranged renal cell carcinoma with osseous metaplasia.
An adult patient had an ALK-rearranged renal cell carcinoma. The tumor showed varied growth patterns in a mucinous background, with a small peripheral focus of osseous metaplasia.
Surgical Procedure to Optimize the Esthetic and Osseous Outcomes for Young Adults with Large Periradicular Defects: Two Case Reports.
The report describes two young adults with teeth affected by internal root resorption or persistent large periapical lesions after nonsurgical endodontic treatment.
Reconstruction of the Burned Nose Using an Expanded Skin-Grafted Forehead Flap, Delayed Turnover Flaps, and Indocyanine Green Perfusion Assessment.
A 35-year-old man developed severe nasal deformity and airway compromise after a flame burn involving about 20% of total body surface area.
Late Gastric Remnant Necrosis Associated with Paraesophageal Hernia After Roux-en-Y Gastric Bypass.
A 65-year-old man presented nearly 20 years after Roux-en-Y gastric bypass with acute left upper quadrant pain, nausea, and vomiting.
Shotgun metagenomic characterization of human adenovirus F40 and a non-cpe Clostridium perfringens strain in pediatric prolonged diarrhea: a genome-resolved case study.
A child with prolonged diarrhea had adenovirus identified as the sole pathogen by routine testing. Shotgun metagenomic sequencing of stool confirmed human adenovirus F40 (HAdV-F40), phylogenetically distinct from…
Carpal Osteomyelitis Caused by Mycobacterium Intracellulare Treated with Vascularized Bone Graft Reconstruction: A Case Report.
An 81-year-old man had progressive wrist swelling over 5 years, with diffuse carpal destruction attributed to Mycobacterium intracellulare osteomyelitis.
Clopidogrel-induced insulin autoimmune syndrome: A case report and analysis of clinical characteristics in Chinese patients.
A 69-year-old Chinese man developed hypoglycemic symptoms and was diagnosed with insulin autoimmune syndrome after starting clopidogrel.
Multidisciplinary Single Stage Surgical Management of Advanced Breast Carcinoma With Concomitant Left Atrial Myxoma.
A 58-year-old woman with locally advanced invasive mucinous breast carcinoma had a progressive fungating mass despite neoadjuvant chemotherapy and radiotherapy.
Pediatric suprasellar primary CNS lymphoma with cavernous sinus invasion and ischemic stroke: a case report and systematic review.
A 12-year-old immunocompetent girl presented with high fever, severe headache, and diplopia, followed by rapid neurological deterioration.
Angiosarcoma in the Setting of Vascular Procedures: A Systematic Review and Our Experiences.
Angiosarcoma is a rare, aggressive endothelial malignancy with a poor prognosis; diagnosis is often delayed by vague symptoms, nonspecific imaging, and challenging histopathology.
Chronic erythema nodosum leprosum in Hansen's disease: a challenging clinical management.
A 34-year-old Moroccan man with multibacillary Hansen’s disease developed chronic erythema nodosum leprosum (ENL), with recurrent systemic and cutaneous flares requiring prolonged immunomodulatory treatment.
Imaging and Clinical Features of Secondary Spinal Cord Lymphoma: A 2-Center Case Series.
This two-center case series describes 18 cases of secondary spinal cord lymphoma. The authors examined spinal MRI findings and their relationship to intracranial disease, systemic lymphoma, and clinical features.
Short communication: Urinary schistosomiasis mimicking a bladder tumour in a Somali student diagnosed in Türkiye.
A 20-year-old Somali student living in Türkiye presented with painless visible haematuria and lower urinary tract symptoms. He had a history of freshwater exposure in Somalia.
Pulmonary-Cardiac Involvement in a Patient with IgA Vasculitis.
A 41-year-old woman with biopsy-proven IgA nephropathy presented with progressive dyspnea, hemoptysis, and a painful purpuric rash.
Children of advanced cancer patients need better support: A case report.
This case study describes a parent with advanced cancer and minor children who needed support in discussing the diagnosis, preparing the children for the possibility of death, and addressing anticipatory grief.
"Fatal venous thromboembolism and divergent phenotypes in DOCK8 deficiency: a three-sibling case series".
Three siblings with genetically confirmed DOCK8 deficiency had early-onset atopic dermatitis, recurrent respiratory infections, and failure to thrive. All developed bronchiectasis and severe viral infections.
Duodenal Adenocarcinoma Recurrence Limited to the Choledochojejunostomy After Pancreaticoduodenectomy: A Case Suggesting Intraluminal Implantation With a Distinct Mucin Phenotypic Shift.
A 59-year-old man developed recurrence at the choledochojejunostomy 27 months after pancreaticoduodenectomy for duodenal adenocarcinoma, despite five surgically created raw surfaces.
Concomitant Robotic Pericardial Window and Mediastinal Tumour Biopsy Under Intraoperative Ultrasound Guidance.
An 83-year-old woman presented with an undiagnosed mediastinal mass and a symptomatic, loculated pericardial effusion. She underwent a robotic pericardial window and mediastinal tumour biopsy performed together under…
Rare Sites of Metastases to the Breast and Integumentary System in Advanced Cervical Cancer at Initial Presentation in Eastern Uganda: A Case Report.
A 72-year-old woman in Uganda presented after 13 months of intermittent postmenopausal bleeding and abnormal vaginal discharge, despite repeated treatment for presumed urinary and sexually transmitted infections.
Metagenomic Next-Generation Sequencing of Mycoplasma hominis Infection in an Immunocompromised Patient: A Case Report.
A 52-year-old immunocompromised man developed persistent soft-tissue infection after a wooden splinter injury, with recurrent fever, wound pain, swelling, and exudation.
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