Clopidogrel-induced insulin autoimmune syndrome: A case report and analysis of clinical characteristics in Chinese patients.
Haoyue Liu, Jing Wang, Yingying Wang et al.
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Case in brief
A 69-year-old Chinese man developed hypoglycemic symptoms and was diagnosed with insulin autoimmune syndrome after starting clopidogrel. His condition improved after clopidogrel was stopped and replaced with ticagrelor, alongside dietary modification and voglibose treatment. The report also reviewed published Chinese cases and compared their clinical characteristics with cases from other countries; the abstract does not provide further case-level diagnostic findings.
What made this case unusual
The report describes insulin autoimmune syndrome in association with clopidogrel, a drug-related adverse event that may be underrecognized when patients present with hypoglycemia.
Diagnostic / clinical pearl
In a patient with hypoglycemia, consider a medication-related cause; the report highlights clopidogrel-associated insulin autoimmune syndrome as a potential diagnostic consideration.