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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

AllClinical ResearchCase Reports
FeaturedClinical ResearchPreventive Medicine / Public Health

2025 National Guidelines on the Mediterranean Diet: Executive Summary of a Joint Report by Italian Scientific Societies and the National Institute of Health Task Force on Clinical Practice Guidelines.

Nutr RevNov 12, 2026

This systematic review and practice guideline, developed by a multidisciplinary panel using NUTRIGRADE, assessed Mediterranean diet evidence across nine health domains and one economic domain.

Why it matters

The guideline synthesizes evidence across multiple clinical and public health domains, indicating that dietary patterns may be relevant to prevention and outcomes across a broad range of non-communicable diseases.

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Also worth knowing

Clinical ResearchAnesthesiology

Effect of discontinuing antihypertensives on perioperative hypotension in older patients before non-cardiac surgery: multicentre, randomised, double blind, controlled trial.

This multicentre, randomised, double blind, placebo controlled trial assessed whether withholding ACE inhibitors or ARBs on the morning of surgery reduces perioperative hypotension in older adults undergoing non-cardiac…

BMJNov 11, 2026Read summary
Clinical ResearchCardiology

Prevalence and Consequences of Guideline-Directed Indications for Aortic Valve Replacement in the EARLY TAVR Trial.

This analysis of the multicenter randomized EARLY TAVR trial examined how often patients with asymptomatic severe aortic stenosis had ACC/AHA Class II indications for aortic valve replacement (AVR), and whether these…

JACC Cardiovasc IntervNov 9, 2026Read summary
Clinical ResearchCardiology

Left bundle branch area vs biventricular pacing for cardiac resynchronization therapy: the LEFT-BUNDLE-CRT trial.

The multicentre, randomized, non-inferiority LEFT-BUNDLE-CRT trial compared left-bundle branch area pacing (LBBAP) with biventricular pacing (BiVP) for cardiac resynchronization in patients with guideline-based…

Eur Heart JNov 10, 2026Read summary
Clinical ResearchCardiology

A nurse-coordinated intervention programme vs standard of care after an acute coronary syndrome: the ALLEPRE trial.

The multicentre, pragmatic, randomized ALLEPRE trial compared a nurse-coordinated prevention programme with hospital standard care in patients recovering from acute coronary syndrome.

Eur Heart JNov 10, 2026Read summary
Clinical ResearchCardiologyOpen access

Specialist Referral for Cardiovascular Risk in Patients With Prostate Cancer: A Randomized Clinical Trial.

This multicenter randomized clinical trial tested whether routine cardiovascular-specialist referral improved risk-factor control and cardiovascular outcomes in patients with prostate cancer who were starting or had…

JAMA Intern MedNov 1, 2026Read summary
Clinical ResearchCardiology

Mitral regurgitation and all-cause mortality in acute heart failure: a meta-analysis.

This meta-analysis examined the association between mitral regurgitation (MR) and all-cause mortality in acute heart failure (AHF), pooling 27 studies with 73 363 patients and an average follow-up of 1.9 years.

ESC Heart FailNov 6, 2026Read summary
Clinical ResearchCardiology

Safety and efficacy of cerebral embolic protection devices during TAVI: a meta-analysis and sequence analysis of trials.

This systematic review and meta-analysis of randomized trials assessed cerebral embolic protection (CEP) devices during transcatheter aortic valve implantation (TAVI).

Arq NeuropsiquiatrNov 6, 2026Read summary
Clinical ResearchCardiology

Angiotensin receptor neprilysin inhibitors and renal outcomes in patients with heart failure: a systematic review and meta-analysis.

This systematic review and meta-analysis examined renal outcomes with angiotensin receptor neprilysin inhibitors (ARNi) versus renin-angiotensin-aldosterone system inhibitors (RAASi) alone in patients with heart…

ESC Heart FailNov 6, 2026Read summary
Clinical ResearchCardiologyOpen access

Cardiovascular outcomes of glucagon-like peptide-1 receptor agonists: A systematic review.

This systematic review evaluated 12 cardiovascular outcome-based randomised controlled trials of GLP-1 receptor agonists (GLP1RAs): 10 in people with type 2 diabetes (T2D), one in people with overweight or obesity and…

Am J Health Syst PharmNov 10, 2026Read summary
Clinical ResearchCardiology

Clinical outcomes in various coronary artery bypass grafting techniques: A systematic review and network meta-analysis.

This systematic review and frequentist network meta-analysis compared conventional, minimally invasive, and robotic coronary artery bypass grafting (CABG), including nine sub-techniques, using observational studies and…

PLoS OneNov 5, 2026Read summary
Clinical ResearchCardiothoracic Surgery

Multivessel Versus Single-Vessel Coronary Endarterectomy as an Adjunct to Coronary Artery Bypass Grafting: A Meta-Analysis of Short-Term Outcomes and Implications for Target-Vessel Selection.

This meta-analysis compared short-term outcomes after single-vessel versus multivessel coronary endarterectomy (CE) performed with coronary artery bypass grafting (CABG), using studies that reported both groups within…

Interdiscip Cardiovasc Thorac SurgNov 3, 2026Read summary

Showing 12 of 64 publications that cleared our clinical screen in the last 14 days.

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