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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

FeaturedClinical ResearchPreventive Medicine / Public Health

2025 National Guidelines on the Mediterranean Diet: Executive Summary of a Joint Report by Italian Scientific Societies and the National Institute of Health Task Force on Clinical Practice Guidelines.

Nutr RevNov 12, 2026

This systematic review and practice guideline, developed by a multidisciplinary panel using NUTRIGRADE, assessed Mediterranean diet evidence across nine health domains and one economic domain.

Why it matters

The guideline synthesizes evidence across multiple clinical and public health domains, indicating that dietary patterns may be relevant to prevention and outcomes across a broad range of non-communicable diseases.

Read summary

Also worth knowing

Clinical ResearchEndocrinology

Plozasiran for Severe Hypertriglyceridemia and Risk of Pancreatitis.

Two double-blind, placebo-controlled randomized trials evaluated plozasiran in 757 adults with severe hypertriglyceridemia.

N Engl J MedNov 5, 2026Read summary
Clinical ResearchEndocrinology

Effects of Vitamin D Supplementation in Combination With Exercise Training on Body Composition and Muscular Strength in Adults: A Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.

This systematic review and dose-response meta-analysis of randomized controlled trials assessed whether vitamin D supplementation added to exercise improves body composition or muscular strength compared with exercise…

Nutr RevNov 12, 2026Read summary
Clinical ResearchUrology

Exploring the Association Between Cannabis Use and Male Reproductive Parameters: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined associations between cannabis use and male reproductive parameters. It included 18 studies reporting sperm outcomes (5,766 patients; 6,231 samples) and hormonal outcomes…

Int Braz J UrolNov 12, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Regimens of vitamin D supplementation for women during pregnancy.

This updated Cochrane systematic review and meta-analysis assessed randomised trials of vitamin D regimens during pregnancy in women without pre-existing conditions or multiple pregnancies.

Cochrane Database Syst RevNov 11, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Whole-grain consumption and cardiometabolic risk: a meta-analysis of randomized trials.

This meta-analysis of randomized trials assessed how whole-grain intake affects cardiometabolic risk factors. It included 87 trials (101 publications) and estimated effects per 48 g/day increment in whole grains (dry…

Eur Heart JNov 10, 2026Read summary
Clinical ResearchCardiologyOpen access

Cardiovascular outcomes of glucagon-like peptide-1 receptor agonists: A systematic review.

This systematic review evaluated 12 cardiovascular outcome-based randomised controlled trials of GLP-1 receptor agonists (GLP1RAs): 10 in people with type 2 diabetes (T2D), one in people with overweight or obesity and…

Am J Health Syst PharmNov 10, 2026Read summary
Clinical ResearchGeriatrics

Effect of Exercise Interventions on Sarcopenia-Related Outcomes in Older Adults With Type 2 Diabetes: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed structured exercise versus nonexercise control in adults with type 2 diabetes whose mean age was at least 65 years.

Geriatr Gerontol IntNov 1, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Glycemic control and weight loss benefits of fixed-ratio combinations of basal insulins and GLP1 receptor agonists in type 2 diabetes: A systematic review and network meta-analysis.

This systematic review and network meta-analysis compared fixed-ratio combinations of basal insulin and GLP-1 receptor agonists with basal insulin alone in adults with type 2 diabetes.

EndocrineOct 31, 2026Read summary
Clinical ResearchPediatricsOpen access

Fluid choice in pediatric diabetic ketoacidosis: a Systematic Review and Meta-Analysis.

This systematic review and meta-analysis compared balanced electrolyte solutions (BES) with 0.9% saline for fluid resuscitation in children with diabetic ketoacidosis (DKA), including randomized trials and observational…

Eur J PediatrNov 3, 2026Read summary
Clinical ResearchPediatrics

Effects of Parent-Involved Digital Health Interventions on Adiposity-Related Outcomes and Behaviors in Children and Adolescents With Overweight or Obesity: Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined randomized controlled trials of parent-involved digital health interventions for children and adolescents with overweight or obesity.

J Med Internet ResOct 30, 2026Read summary
Clinical ResearchCardiology

Sex differences in cardiovascular-kidney-metabolic syndrome: the FINE-HEART pooled analysis.

This prespecified pooled analysis combined participant-level data from three trials involving people with chronic kidney disease and type 2 diabetes or heart failure with mildly reduced or preserved ejection fraction.

Eur Heart JNov 10, 2026Read summary

Showing 12 of 58 publications that cleared our clinical screen in the last 14 days.

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