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1303 articles

May 202624

Clinical ResearchPsychiatry

The role of self-criticism and self-compassion in psychotic experiences and associated distress - Risk or resilience? A systematic literature review.

This systematic literature review examined associations between self-criticism, self-compassion and psychotic experiences—including their frequency, severity, endorsement and associated distress—in clinical and…

Psychol PsychotherMay 24, 2026Read summary
Clinical ResearchPsychiatry

Effect of continuation treatment on health-related quality of life in remitted psychotic depression.

This randomized controlled trial investigated the impact of continuation treatment with sertraline plus olanzapine on health-related quality of life (HRQOL) in 126 individuals aged 18 to 85 with remitted psychotic…

J Affect DisordMay 23, 2026Read summary
Clinical ResearchPsychiatry

Episode duration and severity as predictors of placebo response in major depressive disorder.

This randomized controlled trial analyzed the impact of episode duration and severity on placebo response in major depressive disorder across seven studies involving 3,647 participants.

J Affect DisordMay 23, 2026Read summary
Clinical ResearchPsychiatryOpen access

The Impact of Untreated Attention-Deficit/Hyperactivity Disorder on Motor Vehicle Accidents: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined the relationship between untreated Attention-Deficit/Hyperactivity Disorder (ADHD) and motor vehicle accidents (MVAs).

Adv TherMay 23, 2026Read summary
Clinical ResearchNeurology

Mediating effects of depression, stigma, and self-efficacy on self-management improvement in an evidence-based epilepsy self-management program.

This randomized controlled trial evaluated the mediating effects of depression, self-efficacy, and stigma on self-management improvements in 160 individuals with epilepsy participating in the SMART intervention.

Epilepsy BehavMay 22, 2026Read summary
Clinical ResearchPsychiatry

Cognitive behavioural therapy compared to control conditions in treating bulimia nervosa and binge-eating disorder: A systematic review and meta-analysis.

This systematic review and meta-analysis examined randomized controlled trials of cognitive behavioural therapy (CBT) versus control conditions for bulimia nervosa and binge-eating disorder.

Br J Clin PsycholMay 22, 2026Read summary
Clinical ResearchPsychiatry

Effects of bupropion and repetitive transcranial magnetic stimulation (rTMS) on sexual function, depression severity and cognitive performance in individuals with major depressive disorder - results from a double-blind, sham-controlled randomized intervention.

This randomized controlled trial investigated the effects of adjuvant repetitive transcranial magnetic stimulation (rTMS) on sexual function, depression severity, and cognitive performance in 40 inpatients with major…

J Psychiatr ResMay 21, 2026Read summary
Clinical ResearchPsychiatry

Unravelling the complexities of alcohol use in the context of loneliness and stress: a systematic review and proposed model.

This systematic review analyzed 39 studies to explore the relationship between alcohol use, loneliness, and stress in adult, non-clinical populations.

Physiol BehavMay 21, 2026Read summary
Clinical ResearchPsychiatryOpen access

Effectiveness and safety of hyperbaric oxygen therapy for psychiatric disorders: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effectiveness and safety of hyperbaric oxygen therapy (HBOT) in adults with psychiatric disorders, including major depressive disorder (MDD), PTSD, and anxiety.

Psychiatry Clin NeurosciMay 21, 2026Read summary
Clinical ResearchPsychiatryOpen access

White matter microstructure in relatives of people with schizophrenia or bipolar disorder: an ENIGMA meta-analysis.

This meta-analysis examined white matter microstructure in unaffected first-degree relatives of individuals with bipolar disorder (FDR-BD) and schizophrenia (FDR-SZ) compared to controls.

Mol PsychiatryMay 21, 2026Read summary
Clinical ResearchPsychiatry

Effect of Behavioral Weight Management Interventions on Symptoms of Binge-Eating Disorder and Bulimia Nervosa: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed behavioral weight management interventions and eating-disorder symptoms in people diagnosed with binge-eating disorder (BED) or bulimia nervosa (BN).

Obes RevMay 21, 2026Read summary
Clinical ResearchPsychiatry

Smartphone-delivered cognitive behavioral therapy for subthreshold depression with physical comorbidities: Evidence from the RESiLIENT trial.

This randomized controlled trial analyzed the effectiveness of smartphone-delivered cognitive behavioral therapy (CBT) for subthreshold depression in 3577 participants, including those with physical comorbidities.

J Affect DisordMay 20, 2026Read summary
Clinical ResearchPsychiatry

Cost-effectiveness of integrated prevention for late-life depressive symptoms: Real-world findings from a large-scale pragmatic trial ("JoyAge").

This pragmatic non-randomised controlled trial evaluated the cost-effectiveness of the JoyAge integrated prevention program for late-life depression in a sample of 3,416 participants.

J Affect DisordMay 20, 2026Read summary
Clinical ResearchPsychiatry

Bipolar disorder and the risk of developing dementia - a systematic review and meta-analysis.

This systematic review and meta-analysis examined the risk of dementia in patients with bipolar disorder, analyzing data from 22 studies involving 185,306 patients with bipolar disorder and 10,702,744 without.

Curr Opin PsychiatryMay 20, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Supporting at-risk mothers across perinatal period: a randomized controlled trial' (SMART): A development study.

The SMART study is a randomized controlled trial that developed a mobile health application aimed at supporting at-risk mothers during the perinatal period.

MidwiferyMay 20, 2026Read summary
Clinical ResearchPsychiatry

Auditory verbal hallucination and suicide: a systematic review.

This systematic review examined the relationship between auditory verbal hallucinations (AVH) and various dimensions of suicidality across clinical populations.

Psychiatry ResMay 20, 2026Read summary
Clinical ResearchPsychiatry

Comparative diagnostic accuracy of panic provocation tests: A meta-analysis.

This meta-analysis evaluated the diagnostic accuracy of various panic provocation tests in a population of 5693 participants across 123 studies.

J Psychiatr ResMay 20, 2026Read summary
Clinical ResearchPsychiatry

Understanding specificity in immune-brain pathways: A systematic review of differential associations between individual cytokines and brain structure and function measured through magnetic resonance imaging in humans.

This systematic review evaluates the associations between individual cytokines and brain structure and function in humans, focusing on studies involving depressed and healthy participants under 65.

Brain Behav ImmunMay 20, 2026Read summary
Clinical ResearchPsychiatryOpen access

An opioid-withholding human laboratory paradigm during opioid agonist treatment for opioid use disorder and chronic pain: Phase- and dose-dependent effects of cannabidiol.

This randomized controlled trial investigated the effects of cannabidiol (CBD) on pain modulation, craving, and cognition in 23 individuals with opioid use disorder (OUD) and chronic pain receiving opioid agonist…

NeuropsychopharmacologyMay 20, 2026Read summary
Clinical ResearchNephrology

Clozapine-Induced Acute Interstitial Nephritis: A Systematic Review.

This systematic review summarised published cases of acute interstitial nephritis (AIN) associated with clozapine, using a search of four databases and independent study assessment. Thirteen cases were included.

J Clin PsychopharmacolMay 20, 2026Read summary
Clinical ResearchPsychiatry

Effects of aerobic vs. resistance exercise on anxiety reduction and emotional interference in young women with premenstrual syndrome: A randomized controlled fNIRS study.

This randomized controlled trial investigated the effects of 8 weeks of aerobic versus resistance exercise on anxiety and emotional interference in female university students with premenstrual syndrome (PMS).

J Affect DisordMay 19, 2026Read summary
Clinical ResearchGeriatrics

Treating insomnia in mild cognitive impairment: a novel approach combining transcranial magnetic stimulation with cognitive behavioral therapy.

This Phase I/II clinical trial investigates the feasibility and preliminary efficacy of combining repetitive transcranial magnetic stimulation (rTMS) with cognitive behavioral therapy for insomnia (CBT-I) in 30…

Int Rev PsychiatryMay 19, 2026Read summary
Clinical ResearchPsychiatryOpen access

Effect of meditation on clinical symptoms and gray matter volume in chronic schizophrenia: a randomized controlled trial.

This randomized controlled trial investigated the effects of meditation on clinical symptoms and gray matter volume in 58 male inpatients with chronic schizophrenia.

Eur Arch Psychiatry Clin NeurosciMay 19, 2026Read summary
Clinical ResearchPsychiatryOpen access

Efficacy and safety of Nrf2 activators for schizophrenia: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the efficacy and safety of Nrf2 activators in conjunction with antipsychotic treatments for schizophrenia, involving 16 randomized-controlled trials with 953…

Eur Arch Psychiatry Clin NeurosciMay 19, 2026Read summary

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