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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

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Clinical ResearchPsychiatry

Prolonged exposure, eye movement desensitization and reprocessing therapy, and cognitive restructuring versus waiting-list for individuals with PTSD and psychosis (RE.PROCESS): A multicenter, four-arm, assessor-masked, superiority randomized controlled trial.

The multicenter, assessor-masked RE.PROCESS randomized controlled trial compared Prolonged Exposure (PE), eye movement desensitization and reprocessing (EMDR), and Cognitive Restructuring (CR), each alongside usual…

Psychol MedNov 9, 2026Read summary
Clinical ResearchEmergency MedicineOpen access

Efficacy of Technology-Augmented Behavioral Counseling for Risky Firearm Behaviors: A Randomized Clinical Trial.

This two-arm randomized clinical trial tested IntERact, a 30-day program combining telehealth behavioral counseling and tailored smartphone content, against enhanced usual care among 373 emergency department patients…

JAMA PediatrNov 1, 2026Read summary
Clinical ResearchEmergency MedicineOpen access

Telehealth Treatment of Anxiety in Patients With Low-Risk Chest Pain in the Emergency Department: The PACER Randomized Clinical Trial.

The PACER multicentre, three-group randomised comparative effectiveness trial tested peer-supported internet-based cognitive behavioural therapy (iCBT) and therapist-delivered telehealth CBT against primary care…

JAMA Intern MedNov 1, 2026Read summary
Clinical ResearchPsychiatryOpen access

Effectiveness of guided internet-delivered cognitive behavioral therapy for insomnia in autistic adults (i-Sleep Autism): a randomized controlled trial.

This randomized controlled trial evaluated a 5-week, guided internet-delivered cognitive behavioral therapy intervention adapted for autistic adults with insomnia.

SleepNov 10, 2026Read summary
Clinical ResearchNeurologyOpen access

Efficacy of cognitive behavioral therapy for anxiety and depression symptoms in Parkinson's disease patients: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed cognitive behavioral therapy (CBT) for anxiety and depressive symptoms in adults with Parkinson’s disease (PD), pooling 21 randomized controlled trials involving 892…

Neurol SciNov 5, 2026Read summary
Clinical ResearchPediatrics

Effects of bystander interventions on school bullying: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed school-based bystander interventions for bullying and cyberbullying among children and adolescents, drawing on 23 experimental and quasi-experimental controlled studies.

Rev Esc Enferm USPNov 2, 2026Read summary
Clinical ResearchPediatrics

Therapeutic Horseback Riding for Youth With Autism and Psychiatric Comorbidities: A Randomized Trial.

This multisite randomized controlled trial evaluated equine-assisted activities in youth aged 6–16 years with autism and psychiatric comorbidity.

PediatricsNov 1, 2026Read summary
Clinical ResearchPsychiatryOpen access

Dose-Dependent Effect of Crocin on Depressive and Anxiety Symptom Scores: A GRADE-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This GRADE-assessed systematic review and meta-analysis examined dose-response associations between crocin supplementation and depressive and anxiety symptom scores in 14 randomized controlled trials.

Depress AnxietyOct 30, 2026Read summary
Clinical ResearchPsychiatry

The Role of Stress-Related Biomarkers, Immune-Inflammatory Pathways, and Genetic Polymorphisms in Cognitive-Behavioral Therapies for Chronic Low Back Pain and Depression: Results From a Randomized Controlled Trial (The IMPACT Study).

This randomized controlled trial examined whether Acceptance and Commitment Therapy (ACT) or Behavioral Activation Therapy for Depression (BATD), each added to usual care, affected biomarkers or clinical outcomes in 114…

Clin J PainNov 11, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Digital Health Interventions for Pregnancy- and Childbirth-Related Posttraumatic Stress Disorder Symptoms in Postpartum Women: Systematic Review and Meta-Analysis.

This systematic review and meta-analysis pooled randomized controlled trials of digital health interventions for postpartum women who had experienced pregnancy- or childbirth-related trauma.

J Med Internet ResNov 11, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Intimate partner violence against women in Ethiopia: An umbrella review of systematic reviews and meta-analyses.

This umbrella review and random-effects meta-analysis synthesized six systematic reviews and meta-analyses, covering 80 primary studies and 43,785 women in Ethiopia, to estimate intimate partner violence (IPV)…

PLoS OneNov 11, 2026Read summary

Showing 12 of 60 publications that cleared our clinical screen in the last 14 days.

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