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845 articles

June 202624

Case ReportPathology (Anatomic & Clinical)

Uncommon Tumor, Unusual Site, and Unconventional Behavior: Report of a Gastric Composite Gangliocytoma/Neuroma and Neuroendocrine Tumor (CoGNET) With Metastases.

A patient was found to have a composite gangliocytoma/neuroma and neuroendocrine tumor (CoGNET) arising in the stomach, an unusual site for this entity.

Int J Surg PatholJun 16, 2026Read case
Case ReportOphthalmology

Lacrimal Gland Dacryolithiasis With Secondary Bacterial Dacryoadenitis: Clinicoradiological Characterization and Review of Literature.

A 32-year-old woman presented with four days of painful right lacrimal gland swelling. MRI showed an enlarged, enhancing gland containing nonenhancing intraglandular foci with low T2 signal and marked restricted…

Ophthalmic Plast Reconstr SurgJun 16, 2026Read case
Case ReportOphthalmology

Pediatric Castleman Disease Manifesting as a Lacrimal Gland Tumor.

A 15-year-old presented with progressive left eye bulging and intermittent periorbital pain. Imaging showed a well-defined, homogeneous, enhancing mass in the left lacrimal gland, with decreased diffusivity, smooth bone…

Ophthalmic Plast Reconstr SurgJun 16, 2026Read case
Case ReportDermatology

Clinicopathological Challenge: Erythematous-Yellowish Leg Plaques in a Young Woman: An Uncommon and Slowly Progressive Condition.

A 24-year-old woman developed multiple firm erythematous-yellowish plaques on the posterior left leg over four months, with additional similar lesions appearing over time.

Int J DermatolJun 16, 2026Read case
Case ReportMedical GeneticsOpen access

Splicing Alterations Associated with Multiple Homozygous TNXB Variants in a Patient with Suspected Classical-Like Ehlers-Danlos Syndrome.

A patient with generalized joint hypermobility, soft, pliable skin, recurrent elbow dislocations, orthostatic dizziness, chronic constipation, and mild mitral valve regurgitation was evaluated for suspected…

Biochem GenetJun 15, 2026Read case
Clinical ResearchOncology (Medical)

ACCURACY OF IMAGE-BASED DEEP LEARNING IN ORAL SQUAMOUS CELL CARCINOMA DIAGNOSIS: A SYSTEMATIC REVIEW AND META-ANALYSIS.

This systematic review and meta-analysis evaluated the effectiveness of image-based deep learning (DL) in diagnosing oral squamous cell carcinoma across 52 studies.

J Evid Based Dent PractJun 13, 2026Read summary
Case ReportPediatrics

Synchronous Undifferentiated Embryonal Sarcoma of the Liver and Fibrolamellar Hepatocellular Carcinoma in a Patient with Adenosine Deaminase Deficiency.

A 7-year-old boy with adenosine deaminase deficiency presented with fever, elevated acute phase reactants, and a heterogeneous cystic liver mass measuring 85 × 60 mm on ultrasonography.

Int J Surg PatholJun 12, 2026Read case
Case ReportOncology (Medical)

Malignant Adenomyoepithelioma Combined with Invasive Ductal Carcinoma of the Breast: A Case Report.

An 85-year-old woman presented with a 5.5 cm mass in the outer quadrant of the left breast. Biopsy was interpreted as metaplastic spindle cell carcinoma, and she underwent total mastectomy.

Int J Surg PatholJun 12, 2026Read case
Case ReportHematology

Extranodal NK/T-Cell Lymphoma Revealed by Hemophagocytic Lymphohistiocytosis: A Case Report.

A 67-year-old man presented with compressive aerodigestive symptoms and cytopenias. Evaluation identified hemophagocytic lymphohistiocytosis (HLH), which led to recognition of extranodal NK/T-cell lymphoma, nasal type.

Int J Lab HematolJun 12, 2026Read case
Case ReportCardiology

Contrast Echocardiography in the Multimodal Diagnosis of a Giant Primary Cardiac Angiosarcoma: A Case Report.

A 26-year-old woman presented with palpitations and dizziness. Transthoracic echocardiography identified a large hypoechoic right atrial mass with pericardial effusion.

J Clin UltrasoundJun 12, 2026Read case
Case ReportDermatology

A 73-Year-Old Man With Eruptive Pruritic Brown Papules.

A 73-year-old man presented with a year-long, progressively spreading pruritic eruption on his lower extremities and forearms. Examination showed brown verrucous papules merging into plaques.

Int J DermatolJun 11, 2026Read case
Case ReportObstetrics & Gynecology

Cervical tuberculosis mimicking carcinoma of the cervix in a patient with long-standing secondary amenorrhea.

A woman in her 40s with 12 years of secondary amenorrhea presented with postcoital bleeding. Examination showed a cervical growth concerning for carcinoma.

Int J Gynaecol ObstetJun 10, 2026Read case
Case ReportPathology (Anatomic & Clinical)

Mullerian Adenosarcomas with Extrauterine Involvement, Sarcomatous Overgrowth and MDM2 Amplification: A Diagnostic Challenge.

The report describes three Müllerian adenosarcomas presenting outside the uterus. All showed extensive sarcomatous overgrowth and MDM2 amplification.

Int J Surg PatholJun 10, 2026Read case
Case ReportPathology (Anatomic & Clinical)

A "Double-Hit" Lymphoma With Plasmablastic Features and Aberrant Keratin Expression Likely Transforming From Follicular Lymphoma.

A patient with a history of follicular lymphoma developed a transformed lymphoma with plasmablastic features and aberrant keratin expression.

Int J Surg PatholJun 10, 2026Read case
Case ReportPathology (Anatomic & Clinical)

Pathological Advances and Clinical Management Insights into Primary Pulmonary Myxoid Sarcoma Harboring the Rare EWSR1 :: CREB1 Fusion.

A 64-year-old woman had a primary pulmonary myxoid sarcoma that had been present for 7 years without symptoms. The tumor was resected, and fluorescence in situ hybridization confirmed an EWSR1::CREB1 fusion, supporting…

Int J Surg PatholJun 10, 2026Read case
Case ReportInfectious DiseasesOpen access

A case of atypical orf virus infection of the hand in an immunocompromised patient.

An immunocompromised post-transplant patient presented with an enlarging exophytic mass on the hand, diagnosed as atypical orf virus infection.

Skeletal RadiolJun 9, 2026Read case
Case ReportPathology (Anatomic & Clinical)

Case Series of Cutaneous Rothia Mucilaginosa Infection and an Important Potential Pitfall Case.

Three immunocompromised patients with hematolymphoid malignancies and profound neutropenia presented with suspected cutaneous infections caused by Rothia mucilaginosa.

Am J DermatopatholJun 9, 2026Read case
Case ReportDermatology

Clinicopathological Challenge: A Rapidly Progressive Bullous Ulcer in a Patient Receiving Gilteritinib.

An 80-year-old woman with therapy-related acute myeloid leukemia developed a painful violaceous papulonodule on her right shin five months after starting gilteritinib.

Int J DermatolJun 9, 2026Read case
Case ReportOncology (Medical)

A Rare Presentation of Multiple Primary Cancers with Extensive Abdominopelvic Cross-Metastasis and Tumor-to-Tumor Metastasis: High-Grade Serous Carcinoma of the Ovary and Well-Differentiated Mucinous Adenocarcinoma of the Appendix.

A 73-year-old woman presented with abdominal distension and complex abdominopelvic masses. Ascitic fluid contained two morphologically distinct malignant cell populations.

Int J Surg PatholJun 9, 2026Read case
Case ReportPathology (Anatomic & Clinical)

The Diagnostic Utility of PRAME in a Case of Trans-Differentiated Melanoma Metastatic to the Heart.

A patient had metastatic melanoma involving the left atrium. The tumor had lost melanocytic differentiation and acquired rhabdomyosarcomatous differentiation, making its diagnosis challenging because melanocytic markers…

Int J Surg PatholJun 9, 2026Read case
Case ReportPathology (Anatomic & Clinical)

Intracranial Mesenchymal Tumor With Rare EWSR1 :: CREM Gene Fusion in an Older Adult Woman: A Case Report and Review of the Literature.

A 60-year-old woman with a history of breast carcinoma presented with a right frontal intracranial mass. Histology showed stellate and spindle cells in abundant myxoid stroma, with positivity for EMA, CD99, desmin, and…

Int J Surg PatholJun 9, 2026Read case
Case ReportPathology (Anatomic & Clinical)

Cervical Teratoma in an Adult Man: A Case Report Including Molecular Characterization and Discussion of Malignant Potential.

A 36-year-old man presented with a cystic neck mass. After diagnostic evaluation, the mass was excised.

Int J Surg PatholJun 9, 2026Read case
Clinical ResearchObstetrics & Gynecology

Tumor budding as a predictive factor of lymph node metastases and survival in endometrial cancer patients: A systematic review and meta-analysis.

This systematic review and meta-analysis examined whether tumor budding (isolated cells or small clusters at the invasive front) is associated with survival and lymph node positivity in endometrial cancer.

Int J Gynaecol ObstetJun 8, 2026Read summary
Case ReportPathology (Anatomic & Clinical)

Malignant Mixed Tumor of the Skin With TRPS1::PLAG1 Fusion.

The report describes a case of malignant mixed tumor of the skin (MMTS), a malignant cutaneous adnexal neoplasm arising through malignant transformation of a benign mixed tumor.

Am J DermatopatholJun 8, 2026Read case

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