Cervical Teratoma in an Adult Man: A Case Report Including Molecular Characterization and Discussion of Malignant Potential.

Int J Surg PatholJun 9, 2026 (epub)
Case ReportPathology (Anatomic & Clinical)General SurgeryOncology (Medical)

Hosamadean Benghashir, Mahir Petkar, Rajen Goyal

✦ AI-curated · Sources linked

Case in brief

A 36-year-old man presented with a cystic neck mass. After diagnostic evaluation, the mass was excised. Histology showed squamous epithelium, sebaceous glands, hair material, and disorganized smooth muscle bundles, supporting teratoma. FISH detected chromosome 12p gain in 24% of nuclei. Testicular ultrasound found no gonadal primary, and the findings established a primary cervical teratoma. The report discusses the lesion’s malignant potential but does not state a malignant outcome.

What made this case unusual

The adult cervical teratoma showed chromosome 12p gain in 24% of nuclei, an unusual molecular finding in this rare head and neck location.

Diagnostic / clinical pearl

In an adult with a cystic neck mass and teratomatous histology, integrate morphology with molecular testing and assess for a gonadal primary; here, testicular ultrasound was negative.

Source

PubMed · PMID 42261685

Published in Int J Surg Pathol. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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