Malignant Adenomyoepithelioma Combined with Invasive Ductal Carcinoma of the Breast: A Case Report.

Int J Surg PatholJun 12, 2026 (epub)
Case ReportOncology (Medical)Pathology (Anatomic & Clinical)

Cao Jin, Sudarshana Roychoudhury

✦ AI-curated · Sources linked

Case in brief

An 85-year-old woman presented with a 5.5 cm mass in the outer quadrant of the left breast. Biopsy was interpreted as metaplastic spindle cell carcinoma, and she underwent total mastectomy. Examination of the resection specimen identified malignant adenomyoepithelioma coexisting with well-differentiated invasive ductal carcinoma. The final diagnosis therefore differed from the biopsy interpretation and revealed two distinct malignant components in the breast mass.

What made this case unusual

The resection showed malignant adenomyoepithelioma alongside well-differentiated invasive ductal carcinoma, a combination that was not identified on the initial biopsy.

Diagnostic / clinical pearl

In a large breast tumor, extensive tissue sampling may be important: limited biopsy findings may not capture coexisting malignant components.

Source

PubMed · PMID 42283097

Published in Int J Surg Pathol. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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