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2000 articles
November 202624
Ascites Presenting as a Peritonitis-Like Manifestation and Liver Injury due to Trabectedin Monotherapy in a Patient With Myxoid Liposarcoma.
An 82-year-old woman with recurrent metastatic myxoid liposarcoma developed liver dysfunction and ascites while receiving trabectedin monotherapy, after 12 cycles.
INDIVIDUAL ARTICLE: Randomized Double-Blind, Placebo-Controlled Study of a Supplement and Serum on Grey Hair.
This randomized, double-blind, placebo-controlled study assessed a topical serum and oral supplement, alone and in combination, in 173 men and women aged 28–65 years with 5–25% grey hair.
Polyneuropathy, Organomegaly, Endocrinopathy, M-Protein, and Skin Changes (POEMS) Syndrome With Characteristic Muscle Biopsy Findings and Without M-Protein.
A 63-year-old woman referred with presumed CIDP had not responded to IVIG or steroids. Her presentation included marked weight loss, papilledema, skin changes, thrombocytosis, thromboembolisms, hemi-diaphragmatic…
Clinical significance of isolated periappendiceal red patch in ulcerative colitis: A systematic review, meta-analysis, and meta-regression.
This systematic review and meta-analysis examined whether an isolated periappendiceal red patch (PARP) is associated with disease extent or outcomes in ulcerative colitis.
Impact of Aspirin Use on Mortality and Cardiac Allograft Vasculopathy After Heart Transplantation: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis examined whether aspirin use was associated with mortality and cardiac allograft vasculopathy (CAV)-related outcomes in heart transplant recipients.
Anatomy-specific Performance of CTA-based AI for Anterior Circulation Occlusion: Systematic Review and Meta-analysis.
This prospectively registered systematic review and diagnostic meta-analysis assessed CTA-based artificial intelligence for detecting anterior-circulation occlusions, using 31 reports involving 15 708 patients.
Vogt-Koyanagi-Harada (VKH) Syndrome Mimicking Bilateral Optic Neuritis.
A 36-year-old man developed progressive bilateral visual loss over 5 days, with papillitis on fundus examination. Brain MRI and CSF were normal, and serum NMO and MOG testing was negative.
Interventions to Increase Organ Donation: A Systematic Review.
This systematic review synthesized United States-based studies of interventions intended to increase organ donation among adults.
Severe Infection Outcomes With SGLT2 Versus DPP-4 Inhibitors in Type 2 Diabetes: A Systematic Review and Active-Comparator Meta-Analysis of Real-World Cohorts.
This systematic review and active-comparator meta-analysis examined real-world severe infection outcomes among people with type 2 diabetes treated with SGLT2 inhibitors versus DPP-4 inhibitors.
Effectiveness of Traditional Chinese Fitness Methods on Depressive Symptoms and Glycaemic Control in Patients With Type 2 Diabetes and Comorbid Depression: A Systematic Review and Meta-Analysis of Taijiquan and Baduanjin.
This systematic review and meta-analysis assessed randomised controlled trials of Taijiquan and Baduanjin in people with type 2 diabetes and comorbid depression. Eight trials, all conducted in China, were included.
Mycobacterium abscessus bacteremia: A narrative literature review based on a case report.
The report describes a catheter-associated bloodstream infection caused by Mycobacterium abscessus subsp. massiliense. The authors also reviewed published M.
Paxalisib with Trastuzumab for HER2-Positive Metastatic Breast Cancer with Active Brain Metastases: A Phase II Trial with Integrated Plasma and CSF ctDNA Analyses.
This phase II trial evaluated brain-penetrant paxalisib plus trastuzumab in patients with active or progressive HER2-positive breast cancer brain metastases, including heavily pretreated patients; leptomeningeal disease…
Systematic Review of Smart Home Assistive Technology Devices for Supporting People With Dementia Living in Their Homes.
This systematic review and meta-analysis assessed smart home and wearable assistive technologies for people with dementia living at home or in supported accommodation.
Preemptive Kidney Transplantation in a Pediatric Patient With Factor XI Deficiency: A Case Report.
A 14-year-old boy with end-stage renal disease from congenital posterior urethral valves underwent preemptive living-donor heterotopic kidney transplantation from his brother.
Cesarean Delivery After Multiple Prior Intraperitoneal Surgeries: A Case Report in a Patient With Crohn Disease.
A 25-year-old woman with Crohn disease in sustained remission had an uncomplicated pregnancy after in vitro fertilization. Her history included five intraperitoneal operations, including bilateral hemicolectomy…
Late Traumatic Avulsion of a Femtosecond LASIK Flap Following a Direct Corneal Injury: A Case Report.
A 34-year-old woman developed pain and reduced vision after a pet bird injured her left cornea, 10 months after uncomplicated femtosecond LASIK.
Immune Checkpoint Inhibitor Rechallenge After Immune-Related Adverse Events: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis pooled observational cohort evidence on restarting immune checkpoint inhibitors (ICIs) after treatment interruption for an immune-related adverse event (irAE).
Efficacy of Technology-Augmented Behavioral Counseling for Risky Firearm Behaviors: A Randomized Clinical Trial.
This two-arm randomized clinical trial tested IntERact, a 30-day program combining telehealth behavioral counseling and tailored smartphone content, against enhanced usual care among 373 emergency department patients…
Serum Insulin-Like Growth Factor-1 (IGF-1) in Parkinson's Disease: A Systematic Review and Meta-Analysis.
This systematic review and random-effects meta-analysis examined observational studies comparing serum IGF-1 in people with Parkinson’s disease (PD) and healthy controls, and studies of associations with PD symptoms.
Effects of Exercise Type and Duration on Pain, Function, and Quality of Life in Patients With Knee Osteoarthritis: A Systematic Review With Bayesian Network Meta-Analysis.
This systematic review with Bayesian network meta-analysis compared aerobic, resistance, and combined exercise for pain, function, and quality of life in people with knee osteoarthritis.
The two-shot protocol. A randomized controlled trial of a novel two-injection ovarian stimulation strategy.
This phase III, single-centre randomised non-inferiority trial compared two sequential corifollitropin alfa (CFA) injections with conventional CFA followed by recombinant FSH in women undergoing elective fertility…
Therapeutic Approaches and Clinical Outcomes of Myeloid/Lymphoid Neoplasms With Eosinophilia Harboring FLT3 Rearrangements: A Systematic Review of 39 Cases.
This systematic review examined treatment approaches and outcomes in 39 reported cases of myeloid/lymphoid neoplasms with eosinophilia harboring FLT3 rearrangements, a rare malignancy without standardized treatment…
False-Positive Prenatal Suspicion of Partial Anomalous Pulmonary Venous Connection: A Benign Confluence Variant Clarified by Cardiac CT.
Prenatal ultrasound raised suspicion of partial anomalous pulmonary venous connection (PAPVC). After birth, echocardiography—limited by acoustic windows and influenced by the prenatal interpretation—also suggested…
First-in-Human Regulatory T Cell-Derived Exosomes Plus Ranibizumab for Refractory nAMD.
This single-centre, prospective, open-label phase 1a dose-escalation trial evaluated the safety and maximum tolerated dose of intravitreal autologous regulatory T cell-derived exosomes (TregExo) coformulated with…
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