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1240 articles

November 202624

Clinical ResearchCardiology

The relationship between sirtuin1 gene polymorphism and coronary heart disease: Systematic review and meta-analysis.

This systematic review and meta-analysis examined associations between four SIRT1 gene polymorphisms and coronary heart disease (CHD), drawing on 9 articles with 1,839 cases and 1,937 controls.

Medicine (Baltimore)Nov 6, 2026Read summary
Clinical ResearchCardiologyOpen access

Acute effects of hibiscus tea versus coffee consumption before prolonged sitting on blood pressure and heart rate variability in adults: a randomized crossover trial.

This randomized crossover trial compared acute cardiovascular responses to hibiscus tea versus coffee before 3 hours of uninterrupted sitting in 24 young, healthy adults.

Eur J NutrNov 6, 2026Read summary
Case ReportCardiology

Left Ventricular Free-Wall Injury During Emergency Pericardial Drainage After Percutaneous Coronary Intervention-Related Coronary Perforation.

A 63-year-old woman developed shock and an enlarging pericardial effusion after PCI for a severely calcified right coronary artery lesion complicated by perforation, which was sealed with a covered stent.

Am J Case RepNov 6, 2026Read case
Clinical ResearchCardiology

Safety and efficacy of cerebral embolic protection devices during TAVI: a meta-analysis and sequence analysis of trials.

This systematic review and meta-analysis of randomized trials assessed cerebral embolic protection (CEP) devices during transcatheter aortic valve implantation (TAVI).

Arq NeuropsiquiatrNov 6, 2026Read summary
Clinical ResearchCardiology

Patient Engagement in a Virtual Cardiac Rehabilitation Platform: Secondary Analysis of the ERA-Nudge Trial.

This secondary analysis of the pragmatic randomized ERA-Nudge trial examined engagement with a smartphone cardiac rehabilitation app among 223 patients at an urban safety-net hospital.

JMIR Mhealth UhealthNov 6, 2026Read summary
Clinical ResearchCardiology

Angiotensin receptor neprilysin inhibitors and renal outcomes in patients with heart failure: a systematic review and meta-analysis.

This systematic review and meta-analysis examined renal outcomes with angiotensin receptor neprilysin inhibitors (ARNi) versus renin-angiotensin-aldosterone system inhibitors (RAASi) alone in patients with heart…

ESC Heart FailNov 6, 2026Read summary
Clinical ResearchCardiology

Differential rates of guideline-directed medical therapy modification in C-MIC and control patients: results from the C-MIC II trial.

This analysis of the multicentre, randomised C-MIC II trial examined whether changes in background heart failure medication influenced outcomes in ambulatory patients with chronic non-ischaemic HFrEF receiving…

ESC Heart FailNov 6, 2026Read summary
Clinical ResearchCardiology

Mitral regurgitation and all-cause mortality in acute heart failure: a meta-analysis.

This meta-analysis examined the association between mitral regurgitation (MR) and all-cause mortality in acute heart failure (AHF), pooling 27 studies with 73 363 patients and an average follow-up of 1.9 years.

ESC Heart FailNov 6, 2026Read summary
Case ReportOncology (Medical)

Postoperative Neuromuscular Paresis and Overlap Syndrome Related to Immune Checkpoint Inhibitors: A Case Report.

A patient receiving immune checkpoint inhibitor therapy developed extremity paresis after proximal humerus resection and reconstruction.

JBJS Case ConnectNov 5, 2026Read case
Clinical ResearchCardiology

Clinical outcomes in various coronary artery bypass grafting techniques: A systematic review and network meta-analysis.

This systematic review and frequentist network meta-analysis compared conventional, minimally invasive, and robotic coronary artery bypass grafting (CABG), including nine sub-techniques, using observational studies and…

PLoS OneNov 5, 2026Read summary
Clinical ResearchCardiology

Effectiveness of nurse-led hypertension interventions on retention, adherence, and blood pressure control among adults in low- and middle-income countries: A systematic review.

This systematic review assessed nurse-led hypertension interventions in primary care among adults in low- and middle-income countries, examining retention, medication adherence, and blood pressure.

PLoS OneNov 5, 2026Read summary
Case ReportCardiology

Perinatal multidisciplinary management for neonates with prenatally-diagnosed congenital complete heart block undergoing early epicardial pacemaker implantation: a retrospective single-center case series.

This retrospective single-center series described four neonates with prenatally diagnosed isolated congenital complete heart block who required early epicardial pacemaker implantation.

J Matern Fetal Neonatal MedNov 4, 2026Read case
Clinical ResearchCardiology

A randomized comparison of comprehensive weight loss intervention vs. usual care on recurrences of atrial fibrillation in obese patients after catheter ablation: HOBIT-AF trial.

The HOBIT-AF randomized controlled trial tested whether a comprehensive weight-loss intervention reduced atrial fibrillation or atrial tachycardia (AF/AT) recurrence after catheter ablation in obese patients.

EuropaceNov 4, 2026Read summary
Clinical ResearchCardiology

Safety and effectiveness of a novel dual-energy radiofrequency/pulsed field ablation catheter: 12-month results of the FlexPulse study.

The FlexPulse study was a global, prospective, single-arm, multicentre clinical trial evaluating a flexible-tip catheter that delivers radiofrequency and pulsed-field energy in people with symptomatic, drug-refractory…

EuropaceNov 4, 2026Read summary
Case ReportMedical GeneticsOpen access

Severe Atherogenic Dyslipidemia in Ataxia-Telangiectasia Despite Cachexia: Mechanistic Insights into Mitochondrial Dysfunction.

A 25-year-old woman with genetically confirmed ataxia-telangiectasia and extreme underweight (body mass index 12.5 kg/m²) developed severe mixed atherogenic dyslipidemia despite modest dietary fat intake and no…

Yale J Biol MedNov 4, 2026Read case
Clinical ResearchOncology (Medical)Open access

Effectiveness of home-based exercise interventions on cardiorespiratory fitness and cancer treatment-related cardiovascular toxicity in cancer survivors exposed to cardiotoxic therapies: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis of randomized controlled trials assessed structured home-based exercise in cancer survivors exposed to cardiotoxic therapies. Ten trials involving 851 participants were included.

Support Care CancerNov 3, 2026Read summary
Case ReportMedical GeneticsOpen access

KARS1-Related Infantile-Onset Progressive Leukoencephalopathy With or Without Deafness: A Novel Variant and Phenotypic Expansion.

A two-year-old Iranian boy born to non-consanguineous parents presented with developmental delay, seizures, and sensorineural hearing loss.

J Mol NeurosciNov 3, 2026Read case
Clinical ResearchCardiologyOpen access

Digital Outreach to Improve Statin Refills in Patients With Low Statin Adherence: The ADHERE-ASCVD Randomized Clinical Trial.

The ADHERE-ASCVD pragmatic, health system-embedded randomized clinical trial tested adaptive digital outreach to prompt statin refills among adults with established ASCVD or high ASCVD risk and recent nonadherence.

JAMANov 3, 2026Read summary
Clinical ResearchCardiothoracic Surgery

Multivessel Versus Single-Vessel Coronary Endarterectomy as an Adjunct to Coronary Artery Bypass Grafting: A Meta-Analysis of Short-Term Outcomes and Implications for Target-Vessel Selection.

This meta-analysis compared short-term outcomes after single-vessel versus multivessel coronary endarterectomy (CE) performed with coronary artery bypass grafting (CABG), using studies that reported both groups within…

Interdiscip Cardiovasc Thorac SurgNov 3, 2026Read summary
Case ReportEndocrinology

Clopidogrel-induced insulin autoimmune syndrome: A case report and analysis of clinical characteristics in Chinese patients.

A 69-year-old Chinese man developed hypoglycemic symptoms and was diagnosed with insulin autoimmune syndrome after starting clopidogrel.

J Int Med ResNov 3, 2026Read case
Case ReportRheumatologyOpen access

Pulmonary-Cardiac Involvement in a Patient with IgA Vasculitis.

A 41-year-old woman with biopsy-proven IgA nephropathy presented with progressive dyspnea, hemoptysis, and a painful purpuric rash.

Methodist Debakey Cardiovasc JNov 3, 2026Read case
Clinical ResearchGeriatricsOpen access

Dapagliflozin attenuates progression from prefrailty to frailty in patients with hypertension and chronic kidney disease.

DAPA-FORTRESS followed prefrail hypertensive adults aged over 65 years with chronic kidney disease (CKD) for 1 year to examine links between renal measures and physical performance, and whether dapagliflozin was…

J Clin InvestNov 2, 2026Read summary
Clinical ResearchCardiology

Drug-drug interactions between statins and antibiotics: A systematic review and meta-analysis of observational studies.

This systematic review and meta-analysis assessed observational evidence on muscle toxicity when statins are used with interacting antibiotics, compared with statin therapy alone.

Indian J PharmacolNov 2, 2026Read summary
Clinical ResearchCardiologyOpen access

Prognostic value of Murray law-based quantitative flow ratio after percutaneous coronary intervention.

This prespecified subgroup analysis of the randomised FAVOR III China trial assessed whether post-PCI Murray law-based quantitative flow ratio (μQFR) was associated with long-term outcomes.

EuroInterventionNov 2, 2026Read summary

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