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1602 articles
November 202624
Digital Outreach to Improve Statin Refills in Patients With Low Statin Adherence: The ADHERE-ASCVD Randomized Clinical Trial.
The ADHERE-ASCVD pragmatic, health system-embedded randomized clinical trial tested adaptive digital outreach to prompt statin refills among adults with established ASCVD or high ASCVD risk and recent nonadherence.
Multivessel Versus Single-Vessel Coronary Endarterectomy as an Adjunct to Coronary Artery Bypass Grafting: A Meta-Analysis of Short-Term Outcomes and Implications for Target-Vessel Selection.
This meta-analysis compared short-term outcomes after single-vessel versus multivessel coronary endarterectomy (CE) performed with coronary artery bypass grafting (CABG), using studies that reported both groups within…
Angiosarcoma in the Setting of Vascular Procedures: A Systematic Review and Our Experiences.
Angiosarcoma is a rare, aggressive endothelial malignancy with a poor prognosis; diagnosis is often delayed by vague symptoms, nonspecific imaging, and challenging histopathology.
Chronic erythema nodosum leprosum in Hansen's disease: a challenging clinical management.
A 34-year-old Moroccan man with multibacillary Hansen’s disease developed chronic erythema nodosum leprosum (ENL), with recurrent systemic and cutaneous flares requiring prolonged immunomodulatory treatment.
TIM3 Blockade with Hypomethylating Therapy Restores NK Cell and Cytotoxic CD4+ T-cell Activity in Patients with AML or MDS.
This phase Ib clinical trial examined immune changes in patients with AML or MDS treated with anti-TIM3 sabatolimab plus decitabine.
Efficacy of artemisinin derivatives and kelch13 mutations in Plasmodium falciparum: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed ACT efficacy and the distribution of pfk13 mutations in studies of uncomplicated Plasmodium falciparum malaria across Asia, Africa, and the Americas.
Acquired haemophilia B in Kyasanur Forest disease: a case series of isolated prolonged activated partial thromboplastin time.
Nine patients with confirmed acute Kyasanur Forest disease had prolonged activated partial thromboplastin time (APTT) with normal prothrombin time.
Clopidogrel-induced insulin autoimmune syndrome: A case report and analysis of clinical characteristics in Chinese patients.
A 69-year-old Chinese man developed hypoglycemic symptoms and was diagnosed with insulin autoimmune syndrome after starting clopidogrel.
Exploratory serum renal biomarker and eGFR responses to high-protein diets during resistance versus concurrent training in resistance-trained men.
This randomized 2 × 2 factorial trial examined renal biomarkers and estimated glomerular filtration rate (eGFR) in resistance-trained men consuming 1.6 or 3.2 g·kg⁻¹·d⁻¹ of protein during 16 weeks of resistance or…
Efficacy of Lumateperone 42 mg in Major Depressive Disorder: Subgroup Analysis of a Phase 3 Randomized, Placebo-Controlled Trial.
This post hoc subgroup analysis of a phase 3, randomized, double-blind, placebo-controlled trial assessed adjunctive lumateperone 42 mg in adults with major depressive disorder and inadequate response to antidepressant…
Shotgun metagenomic characterization of human adenovirus F40 and a non-cpe Clostridium perfringens strain in pediatric prolonged diarrhea: a genome-resolved case study.
A child with prolonged diarrhea had adenovirus identified as the sole pathogen by routine testing. Shotgun metagenomic sequencing of stool confirmed human adenovirus F40 (HAdV-F40), phylogenetically distinct from…
Adjuvant mFOLFOXIRI after curative-intent resection of oligometastatic colorectal cancer: phase II FANTASTIC trial.
The multicentre, non-randomized phase II FANTASTIC trial evaluated adjuvant modified FOLFOXIRI after complete metastasectomy for oligometastatic colorectal cancer and assessed circulating tumour DNA (ctDNA).
Robotic-assisted total knee arthroplasty demonstrates superior early functional outcomes compared with conventional total knee arthroplasty: a quasi-randomised controlled trial.
This quasi-randomised controlled trial compared 1-year outcomes after primary total knee arthroplasty (TKA) in 845 patients treated with robotic-assisted or conventional workflows at one institution.
Transbronchial Cryobiopsy for the Diagnosis of Peripheral Pulmonary Lesions: A Prospective Randomized Controlled Study.
This prospective, single-center randomized controlled study compared radial endobronchial ultrasound with guide-sheath-assisted transbronchial cryobiopsy (TBCB) using a 1.1-mm ultrathin probe with conventional forceps…
Submucosal Tunnel Endoscopic Resection of a Gastric Schwannoma Mimicking a Submucosal Tumor.
A 73-year-old woman with recurrent abdominal distension was found on esophagogastroduodenoscopy to have an 8.2 mm submucosal lesion in the gastric body.
Metagenomic Next-Generation Sequencing of Mycoplasma hominis Infection in an Immunocompromised Patient: A Case Report.
A 52-year-old immunocompromised man developed persistent soft-tissue infection after a wooden splinter injury, with recurrent fever, wound pain, swelling, and exudation.
Addition of probenecid to beta-lactam antibiotics in the treatment of skin and soft tissue infections: a systematic review.
This systematic review assessed the effectiveness and safety of adding probenecid to beta-lactam antibiotics for skin and soft tissue infections (SSTIs).
Colonoscopy surveillance after colorectal cancer surgery: meta-analysis.
This systematic review and meta-analysis examined randomized trials comparing follow-up protocols with versus without colonoscopy within 5 years after colorectal cancer surgery.
Comparative Effectiveness of Non-Pharmacological Interventions for Management of Post-Orthodontic Pain: A Systematic Review and Network Meta-Analysis.
This systematic review and Bayesian network meta-analysis compared nine non-pharmacological approaches for orthodontic pain after fixed-appliance activation.
A phase Ia first-in-human study of BPB-101, a novel trifunctional antibody targeting the GARP/TGF-β complex and PD-L1, in patients with locally advanced or metastatic solid tumors.
This phase Ia, multicenter, first-in-human dose-escalation study evaluated BPB-101, a trifunctional antibody targeting the GARP/TGF-β complex and PD-L1, in previously treated patients with advanced or metastatic solid…
Pediatric suprasellar primary CNS lymphoma with cavernous sinus invasion and ischemic stroke: a case report and systematic review.
A 12-year-old immunocompetent girl presented with high fever, severe headache, and diplopia, followed by rapid neurological deterioration.
Fluid choice in pediatric diabetic ketoacidosis: a Systematic Review and Meta-Analysis.
This systematic review and meta-analysis compared balanced electrolyte solutions (BES) with 0.9% saline for fluid resuscitation in children with diabetic ketoacidosis (DKA), including randomized trials and observational…
Epidemiological, etiological, and antifungal resistance patterns of vulvovaginal Candida spp. infections in Cameroon: A systematic review and meta-analysis.
This systematic review and meta-analysis pooled evidence from 34 studies of vulvovaginal Candida infection and vulvovaginal candidiasis (VVC) in Cameroon.
Multidisciplinary Single Stage Surgical Management of Advanced Breast Carcinoma With Concomitant Left Atrial Myxoma.
A 58-year-old woman with locally advanced invasive mucinous breast carcinoma had a progressive fungating mass despite neoadjuvant chemotherapy and radiotherapy.
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