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1602 articles

November 202624

Clinical ResearchPulmonologyOpen access

Health-related quality of life measures in chronic pulmonary aspergillosis: a systematic review of psychometric validity.

This systematic review assessed health-related quality-of-life (HRQoL) measures and symptom scores used in chronic pulmonary aspergillosis (CPA), synthesising evidence from English-language studies published through May…

Eur Respir RevNov 4, 2026Read summary
Clinical ResearchOrthopedic Surgery

Interventions for adhesive capsulitis: systematic review and network meta-analysis of randomised controlled trials.

This systematic review and network meta-analysis compared treatments for adhesive capsulitis in adults, including 189 randomised controlled trials with 12 988 participants and 59 interventions.

BMJNov 4, 2026Read summary
Case ReportAnesthesiology

Adjunctive Imaging to Confirm Ultrasound-Guided Paravertebral Catheter Tip Position in Children: Case Reports.

The report describes children receiving ultrasound-guided paravertebral catheters for perioperative analgesia during thoracic procedures.

A A PractNov 4, 2026Read case
Clinical ResearchInfectious Diseases

Extended in vivo activity of VRC01 HIV-1 prophylaxis entails initial protective efficacy and subsequent breakthrough infections.

The two parallel randomized antibody-mediated prevention trials assessed whether intravenous VRC01 prevented HIV-1 acquisition, with this analysis extending follow-up through the week 104 final visit.

Sci Transl MedNov 4, 2026Read summary
Clinical ResearchOncology (Medical)

Longitudinal remodeling of the tumor-immune microenvironment during regorafenib, nivolumab, and chemotherapy in advanced gastric cancer.

This phase 1b/2 clinical trial evaluated first-line regorafenib, nivolumab, and chemotherapy in 30 patients with mismatch repair-proficient advanced gastric cancer, alongside longitudinal analysis of tumor biopsies.

Sci Transl MedNov 4, 2026Read summary
Case ReportOncology (Medical)

Resolution of Severe Jaundice Following Hepatic Artery Infusion of Bevacizumab and 5-Fluorouracil With Oral Regorafenib in Metastatic Colorectal Cancer:A Case Report.

A patient with sigmoid colon cancer and recurrent liver metastases, previously treated with surgery, systemic chemotherapy, transcatheter arterial chemoembolization, and radiotherapy, presented with severe jaundice.

Am J Case RepNov 4, 2026Read case
Case ReportNeurologyOpen access

Spinocerebellar Ataxia Type 6 Concurrent with Normal-Pressure Hydrocephalus: A Case Report.

A 73-year-old man with two years of progressive gait disturbance had gaze-evoked nystagmus, dysarthria, limb ataxia, a broad-based shuffling gait, and urinary urgency.

CerebellumNov 4, 2026Read case
Clinical ResearchPreventive Medicine / Public HealthOpen access

Health-centric information and moisture management for the adoption of postharvest practices to reduce mycotoxin risk: evidence from black pepper farmers in Sri Lanka.

This randomized controlled trial examined whether health-centric information and moisture-management interventions, alongside general mycotoxin information and government training, changed postharvest practices among…

Mycotoxin ResNov 4, 2026Read summary
Case ReportNeurologyOpen access

Late-onset Niemann-Pick C disease in a patient with spastic ataxia and hyperkinetic involuntary movements: a case report.

A woman with late-onset Niemann-Pick disease type C1 presented from age 50 with progressive postural instability, falls, spastic ataxia, and prominent upper-limb hyperkinetic movements.

Mol Biol RepNov 4, 2026Read case
Clinical ResearchNeurologyOpen access

Immune checkpoints inhibitors in the treatment of progressive multifocal leukoencephalopathy: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed immune checkpoint inhibitors (ICIs) for progressive multifocal leukoencephalopathy (PML), pooling reports involving 186 patients from 52 articles.

Neurol SciNov 4, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Effects of digital stress-management interventions in breast cancer patients 18 months after intervention access.

This randomized controlled trial examined whether app-based cognitive behavioral (CBI) or mindfulness-based (MBI) stress management was associated with improved outcomes 18 months after access began among patients with…

Breast Cancer Res TreatNov 4, 2026Read summary
Case ReportNeurologyOpen access

A rare neurological adverse event of palbociclib: a chronic inflammatory demyelinating polyneuropathy (CIDP) mimic.

A 43-year-old woman with metastatic HR-positive/HER2-negative breast cancer developed progressive, asymmetric weakness and sensory symptoms about two weeks after starting palbociclib.

Breast Cancer Res TreatNov 4, 2026Read case
Clinical ResearchNephrologyOpen access

Proton pump inhibitors in prevention of cisplatin-induced nephrotoxicity: a systematic review.

This systematic review assessed whether proton pump inhibitor (PPI) co-administration prevents cisplatin-related kidney injury and whether it is safe.

Support Care CancerNov 4, 2026Read summary
Clinical ResearchPulmonology

Systemic corticosteroids in critical illness: an evidence-based framework for clinical decision-making.

This systematic review qualitatively synthesized randomized trials, reviews, and meta-analyses to develop a decision framework for systemic corticosteroids in severe community-acquired pneumonia (sCAP), acute…

Eur J Clin PharmacolNov 4, 2026Read summary
Clinical ResearchNeurology

Efficacy and safety of cenobamate in the treatment of drug-resistant epilepsy: a systematic review and meta-analysis in adult, pediatric, and combined populations.

This systematic review and random-effects meta-analysis assessed cenobamate efficacy and safety for drug-resistant epilepsy in adults, children, and mixed-age populations.

Eur J Clin PharmacolNov 4, 2026Read summary
Clinical ResearchNeurologyOpen access

Effects of Probiotics on Migraine in Children and Adults: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed probiotics for migraine prevention in placebo-controlled trials involving adults and children.

Curr Pain Headache RepNov 4, 2026Read summary
Clinical ResearchCardiology

A randomized comparison of comprehensive weight loss intervention vs. usual care on recurrences of atrial fibrillation in obese patients after catheter ablation: HOBIT-AF trial.

The HOBIT-AF randomized controlled trial tested whether a comprehensive weight-loss intervention reduced atrial fibrillation or atrial tachycardia (AF/AT) recurrence after catheter ablation in obese patients.

EuropaceNov 4, 2026Read summary
Case ReportObstetrics & Gynecology

Maternal Ascites as an Atypical Presentation of Severe Preeclampsia: A Case Report.

A 23-year-old woman at 30 weeks and 2 days’ gestation, admitted with fetal growth restriction and intermittent absent end-diastolic flow on umbilical artery Doppler, developed severe preeclampsia superimposed on chronic…

Am J Case RepNov 4, 2026Read case
Clinical ResearchRheumatology

Conductive and sensorineural hearing impairment in juvenile idiopathic arthritis: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed middle-ear and cochlear function in children with juvenile idiopathic arthritis (JIA) compared with healthy controls.

Rheumatology (Oxford)Nov 4, 2026Read summary
Clinical ResearchRheumatology

Validity of the 2023 ACR/EULAR APS classification criteria for paediatric primary APS: inputs from a systematic literature review.

This systematic literature review and individual participant data-style random-effects meta-analysis assessed the 2023 ACR/EULAR antiphospholipid syndrome (APS) classification criteria in children with primary APS.

Rheumatology (Oxford)Nov 4, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Maternal and Fetal Outcomes in Pregnant Women with Burn Injuries: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis pooled maternal and fetal mortality in pregnant women with burn injuries, using observational studies and case series.

J Burn Care ResNov 4, 2026Read summary
Case ReportPlastic SurgeryOpen access

Topical MSC-Derived Extracellular Vesicles Accelerate Healing of Second-Degree Burns: A Case Report.

A 48-year-old man with deep second-degree burns received a single topical dose of allogeneic bone marrow mesenchymal stem cell-derived extracellular vesicles within 48 hours of injury in an open-label phase 1/2a study.

J Burn Care ResNov 4, 2026Read case
Clinical ResearchEndocrinology

Effects of the integrated care on healthcare utilization and costs among patients with diabetes and depression: a cluster-randomized controlled trial.

This cluster-randomized controlled trial in community health centers in China assessed whether Community-based Integrated Care for Patients with Diabetes and Depression affected healthcare use and costs.

Am J EpidemiolNov 4, 2026Read summary
Case ReportPlastic Surgery

Reconstruction of the Burned Nose Using an Expanded Skin-Grafted Forehead Flap, Delayed Turnover Flaps, and Indocyanine Green Perfusion Assessment.

A 35-year-old man developed severe nasal deformity and airway compromise after a flame burn involving about 20% of total body surface area.

J Burn Care ResNov 4, 2026Read case

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