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2000 articles

November 202624

Clinical ResearchEndocrinology

Severe Infection Outcomes With SGLT2 Versus DPP-4 Inhibitors in Type 2 Diabetes: A Systematic Review and Active-Comparator Meta-Analysis of Real-World Cohorts.

This systematic review and active-comparator meta-analysis examined real-world severe infection outcomes among people with type 2 diabetes treated with SGLT2 inhibitors versus DPP-4 inhibitors.

Endocrinol Diabetes MetabNov 1, 2026Read summary
Case ReportPediatrics

Pediatric Liver Transplantation Following Donation After Circulatory Death Using Normothermic Regional Perfusion: A Novel Application.

A 15-year-old girl with fulminant hepatic failure after acetaminophen overdose underwent liver transplantation using a donation-after-circulatory-death graft recovered with thoracoabdominal normothermic regional…

Pediatr TransplantNov 1, 2026Read case
Case ReportGeneral Surgery

Severe acute gastric volvulus: A case report with perforation and extra-gastric ischemic findings.

A 36-year-old man presented with sudden abdominal distension and respiratory distress, with severe hemodynamic instability and an acute abdomen. Imaging showed intraperitoneal free air, leading to emergency laparotomy.

Ulus Travma Acil Cerrahi DergNov 1, 2026Read case
Clinical ResearchPathology (Anatomic & Clinical)

Salivary biomarkers in periodontal diseases: A systematic review.

This systematic review assessed salivary biomarkers for diagnosing and monitoring periodontitis in systemically healthy people. It included 11 human studies with cross-sectional or interventional designs.

J Am Dent AssocNov 1, 2026Read summary
Case ReportObstetrics & Gynecology

Cesarean Delivery After Multiple Prior Intraperitoneal Surgeries: A Case Report in a Patient With Crohn Disease.

A 25-year-old woman with Crohn disease in sustained remission had an uncomplicated pregnancy after in vitro fertilization. Her history included five intraperitoneal operations, including bilateral hemicolectomy…

Am J Case RepNov 1, 2026Read case
Clinical ResearchCardiology

Home Blood Pressure-Guided Lifestyle Intervention for Elevated Blood Pressure Detected at Workplace Health Checkups: A Randomized Pilot Trial.

This randomized pilot trial evaluated home blood pressure (BP) monitoring as part of lifestyle management for elevated BP detected at workplace health checkups.

J Clin Hypertens (Greenwich)Nov 1, 2026Read summary
Clinical ResearchPathology (Anatomic & Clinical)

Cellular and Histopathological Hallmarks of Acute and Chronic Rejection in Vascular Composite Allografts: A Systematic Review.

This systematic review synthesized human studies describing cellular, immunophenotypic, and histopathological features of acute and chronic rejection in vascular composite allografts (VCAs).

Clin TransplantNov 1, 2026Read summary
Clinical ResearchOncology (Medical)

Streptozotocin-based chemotherapy in advanced PanNETs: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed objective response and progression-free survival with streptozotocin (STZ)-containing chemotherapy in advanced pancreatic neuroendocrine tumours.

Endocr Relat CancerNov 1, 2026Read summary
Clinical ResearchPulmonologyOpen access

PURE PRIME: implementing Pulmonary Rehabilitation in Primary care - a randomized-controlled feasibility trial.

PURE PRIME was a randomized controlled feasibility trial testing pulmonary rehabilitation (PR) in private physiotherapy or exercise physiology practices for people with chronic respiratory disease.

Ann Am Thorac SocNov 1, 2026Read summary
Clinical ResearchEmergency Medicine

Prehospital Pediatric Ventilation Quality Following Use of a Feedback Device: A Randomized Study.

This multicenter, single-anonymized randomized crossover simulation study assessed pediatric manual ventilation by EMS clinicians at 5 agencies across 3 US metropolitan sites.

PediatricsNov 1, 2026Read summary
Clinical ResearchNuclear Medicine

Phase 2 Trial of 89 Zr-Deferoxamine-Daratumumab for CD38-targeted Immuno-PET/CT Detection of Multiple Myeloma.

This prospective phase 2 trial compared CD38-targeted 89Zr-DFO-daratumumab immuno-PET/CT with standard-of-care 18F-FDG PET/CT in 60 participants with multiple myeloma.

RadiologyNov 1, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Clinical outcomes of Day-7 blastocysts: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis compared frozen Day-7 blastocyst transfers with Day-5 and Day-6 transfers.

Hum Reprod UpdateNov 1, 2026Read summary
Case ReportPediatrics

A Neonate With Excessive Weight Loss and Electrolyte Abnormalities.

A 7-day-old girl was hospitalized for excessive weight loss. Initial testing showed hyponatremia and hyperkalemia, prompting evaluation for endocrine, renal, and metabolic causes.

PediatricsNov 1, 2026Read case
Clinical ResearchObstetrics & Gynecology

The Effect of Game-based Mobile Application in Learning Postpartum Hemorrhage Management for Midwifery Students.

This two-phase randomized controlled study developed and evaluated a game-based mobile application for postpartum hemorrhage (PPH) management education.

Comput Inform NursNov 1, 2026Read summary
Case ReportPediatrics

An Infant With Extreme Hypernatremia Treated With Peritoneal Dialysis.

A 34-day-old, 3.6-kg male infant developed serum sodium >200 mmol/L and multiple organ dysfunction after accidental salt poisoning.

PediatricsNov 1, 2026Read case
Case ReportPediatrics

Paraneoplastic Autoimmune Multiorgan Syndrome: Diagnostic Lessons for Pediatricians.

An 11-year-old boy developed subacute erythroblastopenia, followed by polymorphic mucocutaneous findings, severe myositis with a dermatomyositis-like phenotype, and mild hepatitis.

PediatricsNov 1, 2026Read case
Clinical ResearchOrthopedic Surgery

The Effect of Virtual Reality on Anxiety and Vital Signs in Patients Undergoing Total Knee Replacement Surgery: A Randomized Controlled Trial.

This randomized controlled trial evaluated whether intraoperative virtual reality affected anxiety and vital signs in 70 patients undergoing total knee replacement.

Comput Inform NursNov 1, 2026Read summary
Clinical ResearchObstetrics & Gynecology

The two-shot protocol. A randomized controlled trial of a novel two-injection ovarian stimulation strategy.

This phase III, single-centre randomised non-inferiority trial compared two sequential corifollitropin alfa (CFA) injections with conventional CFA followed by recombinant FSH in women undergoing elective fertility…

Hum ReprodNov 1, 2026Read summary
Clinical ResearchEndocrinology

Supraclavicular thermography does not isolate a brown adipose tissue signal during room temperature β-adrenergic stimulation in adults.

Two randomized, single-blind, placebo-controlled crossover trials studied thermogenic responses to β-adrenergic stimulation in healthy adults.

Physiol RepNov 1, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Toxoplasma gondii in Ethiopia: A Systematic Review and Meta-Analysis of Infection Prevalence and Associated Risk Factors in Humans and Animals.

This systematic review and random-effects meta-analysis estimated Toxoplasma gondii prevalence and associated risk factors in humans and ruminants in Ethiopia, using studies published between 2012 and 2025.

Vet Med SciNov 1, 2026Read summary
Clinical ResearchEmergency MedicineOpen access

Pain-Related Outcome Domains and Measures in Randomized Controlled Trials of Treatment for Acute Abdominal Pain: A Systematic Review.

This PRISMA-guided systematic review mapped pain-related outcome domains and measures in randomized controlled trials of acute abdominal pain treatment.

Eur J PainNov 1, 2026Read summary
Case ReportPediatrics

Domino Liver Transplantation Using the Explanted Native Liver of a Multivisceral Transplant Recipient: A Pediatric Case Report and Systematic Review.

A 4-month-old boy underwent multivisceral transplantation after near-total enterectomy complicated by gastric, duodenal, and bladder fistulas.

Pediatr TransplantNov 1, 2026Read case
Case ReportPediatrics

Preemptive Kidney Transplantation in a Pediatric Patient With Factor XI Deficiency: A Case Report.

A 14-year-old boy with end-stage renal disease from congenital posterior urethral valves underwent preemptive living-donor heterotopic kidney transplantation from his brother.

Pediatr TransplantNov 1, 2026Read case
Clinical ResearchDermatology

Clindamycin and bacterial load reduction as prophylaxis for surgical site infection after below-knee flap and graft procedures.

This randomised controlled trial evaluated clindamycin prophylaxis and preoperative chlorhexidine washing in consecutive patients undergoing below-knee flap or graft procedures.

Aust J Gen PractNov 1, 2026Read summary

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