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2000 articles
November 202624
Allan-Herndon-Dudley syndrome associated with SLC16A2 c.1384G>A (p.Gly462Arg): A family case report with retrospective molecular diagnosis in a deceased sibling.
A boy evaluated at 4.3 years had profound developmental delay, abnormal tone, dystonia, muscle atrophy, contractures, and bilateral cryptorchidism.
Testing the EQ-HWB-9 with seven-day versus today recall periods in dementia: variability and recall adherence under health fluctuations.
This mixed-methods randomized study compared “7-day” and “today” EQ-HWB-9 recall periods in people living with dementia and caregiver dyads recruited from German primary care.
Identification of AKAP6 as a candidate gene for charcot-marie-tooth disease: expanding the clinical and molecular spectrum.
A family was evaluated for axonal sensorimotor polyneuropathy. Whole-exome sequencing, with copy-number variant detection and runs-of-homozygosity analysis, identified a homozygous nonsense variant in AKAP6, c.4774 C >…
Delayed Diagnosis of Bilateral Congenital Choanal Obstruction in a 4-Year-Old Girl: Transnasal Repair with Temporary Stenting and Short-Term Outcome: A Case Report.
A 4-year-old girl had lifelong bilateral nasal obstruction, mouth breathing, snoring, poor sleep, easy tiredness, intermittent rhinorrhoea, and recurrent respiratory infections, with breastfeeding difficulty in infancy.
Magnetic resonance neurography-supported L3-L4 radiculitis presenting as refractory peripatellar neuropathic pain in a patient with diabetes: A case report.
A 75-year-old man with longstanding type 2 diabetes developed severe burning, stabbing pain around the left kneecap, with numbness and touch-evoked allodynia but no back pain, typical radicular symptoms, weakness, or…
Delayed pancytopenia following ingestion of wild mushrooms consistent with Hypholoma fasciculare: A case report.
A 57-year-old man presented with fever and generalized weakness about 10 days after eating self-collected wild mushrooms consistent with Hypholoma fasciculare. Testing showed delayed-onset pancytopenia.
The relationship between sirtuin1 gene polymorphism and coronary heart disease: Systematic review and meta-analysis.
This systematic review and meta-analysis examined associations between four SIRT1 gene polymorphisms and coronary heart disease (CHD), drawing on 9 articles with 1,839 cases and 1,937 controls.
Efficacy of diadynamic currents versus transcutaneous electrical nerve stimulation for transcutaneous tibial nerve stimulation in subjects with overactive bladder syndrome: A double-blind randomized controlled trial.
This double-blind randomized controlled trial compared transcutaneous tibial nerve stimulation (TTNS) delivered with diadynamic currents (DDC) or transcutaneous electrical nerve stimulation (TENS) in women aged 18–80…
Bone marrow sarcoidosis in Takayasu arteritis: Case report and literature review.
A 46-year-old woman with confirmed Takayasu arteritis presented with elevated systemic inflammatory markers and diffuse hypermetabolic activity on PET.
Time- and posture-specific management of severe supine hypertension and neurogenic orthostatic hypotension in diabetic autonomic neuropathy: A case report.
A 63-year-old man with insulin-treated type 2 diabetes and hypertension developed worsening orthostatic dizziness and recurrent syncope after antihypertensive intensification, including a rib fracture and loss of…
Subsequent epilepsy surgery after SEEG-guided radiofrequency thermocoagulation: Outcomes and prognostic value of treatment response-a systematic review and meta-analysis.
This systematic review and meta-analysis assessed outcomes after resective, disconnective, or ablative epilepsy surgery in patients previously treated with SEEG-guided radiofrequency thermocoagulation (SEEG-RFTC), and…
Neuromyelitis optica spectrum disorder presenting as rapidly progressive dementia: A case report.
A 64-year-old woman developed rapidly progressive cognitive slowing and memory loss over 10 days, with disorientation, apathy, and inability to recognize family; her MMSE score was 3/30.
Comparative outcomes of Hugo RAS and Versius surgical systems versus da Vinci in four urological procedures: a systematic review.
This PRISMA-guided systematic review compared Hugo RAS and Versius with da Vinci in robot-assisted radical prostatectomy, partial nephrectomy, pyeloplasty, and radical cystectomy.
Development and evaluation of a subjective measurement of geographical hardness-to-reach: a survey of data collectors in a large-scale cluster randomised trial of azithromycin mass drug administration.
This sub-study within a large-scale cluster-randomised trial of azithromycin mass drug administration in Mali developed and evaluated a 14-item survey of village accessibility, completed by 25 data collectors.
Successful rechallenge with almonertinib and corticosteroids after gefitinib-induced interstitial lung disease: A case report and literature review.
A 53-year-old never-smoking woman with stage IV, EGFR L858R-mutant lung adenocarcinoma developed progressive dyspnea and hypoxemia after two months of gefitinib, despite an initial tumor response.
Esketamine-Based Versus Sevoflurane-Based Anesthesia with Dexmedetomidine for Emergence Agitation in Pediatric Corneal Suture Removal: A Randomised Controlled Trial.
Corneal suture removal, particularly microsurgery requiring complete immobility, demands adequate anesthetic depth while ensuring rapid recovery.
Primary splenic angiosarcoma initially diagnosed as littoral cell angioma: A case report of a diagnostic pitfall.
A 71-year-old woman presented with left upper abdominal pain, severe anemia, thrombocytopenia, and a splenic lesion. After splenectomy, the lesion was initially diagnosed as littoral cell angioma; a separate hepatic…
Peptides for male sexual dysfunction: a systematic review of emerging evidence.
This PRISMA-guided systematic review assessed human studies of peptide-based therapies for male sexual function, reproductive hormones, and semen parameters.
Cost-effectiveness of digital health in primary care: a systematic review.
This systematic review examined the cost-effectiveness of digital health interventions compared with usual care among adults receiving primary care.
Intra-arterial tenecteplase during thrombectomy for acute ischemic stroke: the BRETIS-TNK2 trial.
The phase 3 BRETIS-TNK2 multicentre randomised trial compared intra-arterial tenecteplase during endovascular thrombectomy with thrombectomy alone in patients with large-vessel occlusion eligible for treatment within 24…
Clinical characteristics, treatment, and prognosis of sexual-related rectal foreign bodies: a systematic review and meta-analysis.
This systematic review and meta-analysis examined clinical features, management, and outcomes of sexual-related rectal foreign bodies, drawing on 59 case reports, case series, and cohort studies from 22 countries, with…
Curriculum-Aligned Conversational AI to Support Pathology Self-Directed Learning in Preclinical Medical Students: Crossover Randomized Pilot Study.
This crossover randomized pilot study evaluated a curriculum-aligned custom GPT for self-directed pathology learning among 44 second-year medical students at the University of South Carolina, Floyd School of Medicine.
Risk of retinal vascular occlusion following COVID-19 vaccination: A meta-analysis of nearly 15 million individuals.
This systematic review and meta-analysis assessed retinal vascular occlusion after COVID-19 vaccination using five observational studies with 14,877,781 reported participants.
Post-lumbar Puncture Hearing Loss: A Rare Case of Reversible Presumed Secondary Endolymphatic Hydrops.
A 46-year-old man developed sudden left-ear fullness and diplacusis monauralis five days after diagnostic lumbar puncture, together with a post-lumbar puncture headache.
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