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2000 articles
November 202624
Digital Outreach to Improve Statin Refills in Patients With Low Statin Adherence: The ADHERE-ASCVD Randomized Clinical Trial.
The ADHERE-ASCVD pragmatic, health system-embedded randomized clinical trial tested adaptive digital outreach to prompt statin refills among adults with established ASCVD or high ASCVD risk and recent nonadherence.
Co-Designed Text Messaging Intervention for Parents of Children With Early Childhood Caries: Randomized Controlled Trial.
This multisite, assessor-blinded randomized controlled trial evaluated a co-designed, 12-week SMS education and support program for parents of children aged 0 to 6 years with early childhood caries attending six public…
Clinical, neuroimaging and electroencephalographic differences between pediatric and adult HaNDL: a systematic review and pooled individual patient analysis.
This PRISMA 2020-guided systematic review and pooled individual patient analysis compared clinical and ancillary findings in pediatric and adult patients with HaNDL, a self-limited headache syndrome with cerebrospinal…
Acquired haemophilia B in Kyasanur Forest disease: a case series of isolated prolonged activated partial thromboplastin time.
Nine patients with confirmed acute Kyasanur Forest disease had prolonged activated partial thromboplastin time (APTT) with normal prothrombin time.
Children of advanced cancer patients need better support: A case report.
This case study describes a parent with advanced cancer and minor children who needed support in discussing the diagnosis, preparing the children for the possibility of death, and addressing anticipatory grief.
TIM3 Blockade with Hypomethylating Therapy Restores NK Cell and Cytotoxic CD4+ T-cell Activity in Patients with AML or MDS.
This phase Ib clinical trial examined immune changes in patients with AML or MDS treated with anti-TIM3 sabatolimab plus decitabine.
Shotgun metagenomic characterization of human adenovirus F40 and a non-cpe Clostridium perfringens strain in pediatric prolonged diarrhea: a genome-resolved case study.
A child with prolonged diarrhea had adenovirus identified as the sole pathogen by routine testing. Shotgun metagenomic sequencing of stool confirmed human adenovirus F40 (HAdV-F40), phylogenetically distinct from…
Adjuvant mFOLFOXIRI after curative-intent resection of oligometastatic colorectal cancer: phase II FANTASTIC trial.
The multicentre, non-randomized phase II FANTASTIC trial evaluated adjuvant modified FOLFOXIRI after complete metastasectomy for oligometastatic colorectal cancer and assessed circulating tumour DNA (ctDNA).
Spatial Acid-Associated Niches Inform Irinotecan-Based DEB-TACE in Colorectal Liver Metastases: A Multicentre Randomized Trial.
This multicentre randomised trial combined transcriptomic and spatial analyses of colorectal liver metastases (CRLM), laboratory testing of irinotecan-eluting microspheres, and clinical evaluation in 35 patients with…
Clopidogrel-induced insulin autoimmune syndrome: A case report and analysis of clinical characteristics in Chinese patients.
A 69-year-old Chinese man developed hypoglycemic symptoms and was diagnosed with insulin autoimmune syndrome after starting clopidogrel.
Homozygous SCA8 presenting as severe axonal neuropathy without overt cerebellar involvement.
A 35-year-old man with progressive limb weakness beginning at age 15 had severe proximal muscle atrophy and absent deep tendon reflexes, without overt cerebellar signs.
Fluid choice in pediatric diabetic ketoacidosis: a Systematic Review and Meta-Analysis.
This systematic review and meta-analysis compared balanced electrolyte solutions (BES) with 0.9% saline for fluid resuscitation in children with diabetic ketoacidosis (DKA), including randomized trials and observational…
Predictive Accuracy and Procedural Benefits of Software-Enhanced Flow-Diverter Planning: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed whether software simulations improve flow-diverter (FD) planning and procedural outcomes for intracranial aneurysms compared with physician planning.
Benson relaxation technique for perioperative anxiety and depressive symptoms in patients undergoing brain tumor surgery: a clinical trial.
This randomized controlled trial evaluated supervised Benson relaxation technique (BRT) sessions for perioperative anxiety and depressive symptoms in patients undergoing brain tumor resection.
Oncologic efficacy and safety of stereotactic body radiotherapy for oligometastatic non-small cell lung cancer: a systemic meta-analysis.
This systematic review and meta-analysis assessed the efficacy and safety of stereotactic body radiotherapy (SBRT) for oligometastatic non-small cell lung cancer, including analyses by oligometastatic subtype and…
Epidemiological, etiological, and antifungal resistance patterns of vulvovaginal Candida spp. infections in Cameroon: A systematic review and meta-analysis.
This systematic review and meta-analysis pooled evidence from 34 studies of vulvovaginal Candida infection and vulvovaginal candidiasis (VVC) in Cameroon.
Rifamycin use and gut microbial antibiotic resistance genes in cirrhosis: Results from a double-blind, placebo-controlled clinical trial.
This double-blind, placebo-controlled randomized trial assessed changes in gut antimicrobial resistance genes (ARGs) with rifamycin SV MMX (RiVM) in patients with compensated cirrhosis.
Pediatric suprasellar primary CNS lymphoma with cavernous sinus invasion and ischemic stroke: a case report and systematic review.
A 12-year-old immunocompetent girl presented with high fever, severe headache, and diplopia, followed by rapid neurological deterioration.
Robotic-assisted total knee arthroplasty demonstrates superior early functional outcomes compared with conventional total knee arthroplasty: a quasi-randomised controlled trial.
This quasi-randomised controlled trial compared 1-year outcomes after primary total knee arthroplasty (TKA) in 845 patients treated with robotic-assisted or conventional workflows at one institution.
Variation in recommendations for management of pediatric fever and neutropenia across databases and languages: A systematic review of clinical practice guidelines.
This systematic review and content analysis examined evidence-based clinical practice guidelines (CPGs) for fever and neutropenia in children, assessing how database indexing and publication language affected guideline…
Effectiveness of home-based exercise interventions on cardiorespiratory fitness and cancer treatment-related cardiovascular toxicity in cancer survivors exposed to cardiotoxic therapies: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis of randomized controlled trials assessed structured home-based exercise in cancer survivors exposed to cardiotoxic therapies. Ten trials involving 851 participants were included.
Tegmental Heterotopia in PHACE Syndrome: A Previously Undescribed Feature.
The report describes two infants with PHACE syndrome and infratentorial neuroglial heterotopia involving the tectal plate. A 6-week-old infant with a right segmental facial hemangioma and ventricular septal defect had…
Stereotactic radiosurgery for bilateral trigeminal neuralgia: A systematic review and proposed framework for staged treatment.
This systematic review assessed stereotactic radiosurgery (SRS) for medically refractory bilateral trigeminal neuralgia (BTN) in adults.
Radiomics performance to identify high-risk carotid artery plaques: a systematic review.
This systematic review assessed radiomics-based models for identifying high-risk carotid plaques. It included 28 studies involving 6,108 patients, 72.4% of whom were male.
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