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2000 articles

November 202624

Clinical ResearchEndocrinology

Effects of the integrated care on healthcare utilization and costs among patients with diabetes and depression: a cluster-randomized controlled trial.

This cluster-randomized controlled trial in community health centers in China assessed whether Community-based Integrated Care for Patients with Diabetes and Depression affected healthcare use and costs.

Am J EpidemiolNov 4, 2026Read summary
Case ReportInternal Medicine (General)Open access

Pseudo-Metabolic Alkalosis: A Hidden Laboratory Pitfall With Elevated LDH.

A 33-year-old man presented with progressive exertional dyspnea, syncope, and paresthesia. Testing showed pancytopenia, macrocytosis, LDH >3600 U/L, low haptoglobin, and vitamin B₁₂ <68 pg/mL, consistent with pernicious…

Yale J Biol MedNov 4, 2026Read case
Clinical ResearchAnesthesiology

Perioperative respiratory adverse events in children undergoing adenotonsillectomy with laryngeal mask airway versus endotracheal tube ventilation: multicentre, randomised controlled trial.

This multicentre, randomised, parallel-group trial compared laryngeal mask airway (LMA) with endotracheal tube (ETT) ventilation during adenotonsillectomy under general anaesthesia in 400 children aged 2 to under 7…

BMJNov 4, 2026Read summary
Case ReportCardiology

Perinatal multidisciplinary management for neonates with prenatally-diagnosed congenital complete heart block undergoing early epicardial pacemaker implantation: a retrospective single-center case series.

This retrospective single-center series described four neonates with prenatally diagnosed isolated congenital complete heart block who required early epicardial pacemaker implantation.

J Matern Fetal Neonatal MedNov 4, 2026Read case
Case ReportMedical GeneticsOpen access

Severe Atherogenic Dyslipidemia in Ataxia-Telangiectasia Despite Cachexia: Mechanistic Insights into Mitochondrial Dysfunction.

A 25-year-old woman with genetically confirmed ataxia-telangiectasia and extreme underweight (body mass index 12.5 kg/m²) developed severe mixed atherogenic dyslipidemia despite modest dietary fat intake and no…

Yale J Biol MedNov 4, 2026Read case
Clinical ResearchPsychiatry

What works for whom? A systematic mapping review of psychological treatments for adults with longstanding anorexia nervosa.

This systematic mapping review examined quantitative interventional studies of psychological treatments for adults with longstanding anorexia nervosa (AN), searching four databases for studies published between 2005 and…

Eat DisordNov 4, 2026Read summary
Case ReportObstetrics & GynecologyOpen access

Heterotopic pregnancy at Komfo Anokye Teaching Hospital: a case report.

A 34-year-old woman presented after two months of amenorrhoea with acute abdominal pain and haemorrhagic shock. Bedside ultrasound showed a live 8-week intrauterine pregnancy as well as a left adnexal mass and pelvic…

J Med Case RepNov 4, 2026Read case
Case ReportOncology (Medical)

Resolution of Severe Jaundice Following Hepatic Artery Infusion of Bevacizumab and 5-Fluorouracil With Oral Regorafenib in Metastatic Colorectal Cancer:A Case Report.

A patient with sigmoid colon cancer and recurrent liver metastases, previously treated with surgery, systemic chemotherapy, transcatheter arterial chemoembolization, and radiotherapy, presented with severe jaundice.

Am J Case RepNov 4, 2026Read case
Clinical ResearchNeurosurgery

Salovum® reduces mortality in isolated severe traumatic brain injury: a randomized phase II trial.

This prospective, double-blind, placebo-controlled phase II randomized trial tested Salovum® in adults with isolated severe traumatic brain injury receiving intracranial pressure monitoring and neurointensive care at a…

BrainNov 4, 2026Read summary
Clinical ResearchInfectious Diseases

Extended in vivo activity of VRC01 HIV-1 prophylaxis entails initial protective efficacy and subsequent breakthrough infections.

The two parallel randomized antibody-mediated prevention trials assessed whether intravenous VRC01 prevented HIV-1 acquisition, with this analysis extending follow-up through the week 104 final visit.

Sci Transl MedNov 4, 2026Read summary
Clinical ResearchRheumatology

Conductive and sensorineural hearing impairment in juvenile idiopathic arthritis: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed middle-ear and cochlear function in children with juvenile idiopathic arthritis (JIA) compared with healthy controls.

Rheumatology (Oxford)Nov 4, 2026Read summary
Case ReportCardiothoracic SurgeryOpen access

Aortic Mycetoma with Exserohilum .

A patient developed neurologic symptoms two months after root-sparing repair of an ascending aortic aneurysm and aortic valve replacement.

Methodist Debakey Cardiovasc JNov 4, 2026Read case
Clinical ResearchPulmonology

Systemic corticosteroids in critical illness: an evidence-based framework for clinical decision-making.

This systematic review qualitatively synthesized randomized trials, reviews, and meta-analyses to develop a decision framework for systemic corticosteroids in severe community-acquired pneumonia (sCAP), acute…

Eur J Clin PharmacolNov 4, 2026Read summary
Case ReportNeurologyOpen access

A rare neurological adverse event of palbociclib: a chronic inflammatory demyelinating polyneuropathy (CIDP) mimic.

A 43-year-old woman with metastatic HR-positive/HER2-negative breast cancer developed progressive, asymmetric weakness and sensory symptoms about two weeks after starting palbociclib.

Breast Cancer Res TreatNov 4, 2026Read case
Case ReportGeneral Surgery

The Harvesting Oblique Tuberosity (HOT) Technique: A Simplified Clinical Approach for Standardized Connective Tissue Graft Retrieval.

This clinical report presents the harvesting oblique tuberosity (HOT) technique for retrieving autogenous connective tissue grafts from the maxillary tuberosity.

Int J Periodontics Restorative DentNov 4, 2026Read case
Clinical ResearchCardiology

A randomized comparison of comprehensive weight loss intervention vs. usual care on recurrences of atrial fibrillation in obese patients after catheter ablation: HOBIT-AF trial.

The HOBIT-AF randomized controlled trial tested whether a comprehensive weight-loss intervention reduced atrial fibrillation or atrial tachycardia (AF/AT) recurrence after catheter ablation in obese patients.

EuropaceNov 4, 2026Read summary
Case ReportInfectious Diseases

Multidrug-resistant (MDR) Salmonella Typhi spondylodiscitis with vertebral collapse: a case report.

A 49-year-old woman with diabetes and hypertension developed persistent back pain after enteric fever. Imaging showed spondylodiscitis with vertebral collapse, raising concern for tuberculosis or metastatic disease.

Future MicrobiolNov 4, 2026Read case
Clinical ResearchNephrology

Effect of Kunxian capsule, a novel Tripterygium wilfordii preparation, on reducing proteinuria and slowing renal function decline in diabetic kidney disease: a 48-week randomized controlled trial.

This 48-week randomized controlled trial assigned 80 patients with diabetic kidney disease to irbesartan-based standard therapy with or without adjunctive Kunxian capsule.

Ren FailNov 4, 2026Read summary
Case ReportObstetrics & Gynecology

Maternal Ascites as an Atypical Presentation of Severe Preeclampsia: A Case Report.

A 23-year-old woman at 30 weeks and 2 days’ gestation, admitted with fetal growth restriction and intermittent absent end-diastolic flow on umbilical artery Doppler, developed severe preeclampsia superimposed on chronic…

Am J Case RepNov 4, 2026Read case
Clinical ResearchPulmonologyOpen access

The Association Between Chronic Obstructive Pulmonary Disease and Postoperative Delirium: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined whether chronic obstructive pulmonary disease (COPD) is associated with postoperative delirium (POD) in surgical patients.

Int J Chron Obstruct Pulmon DisNov 4, 2026Read summary
Clinical ResearchNeurologyOpen access

Immune checkpoints inhibitors in the treatment of progressive multifocal leukoencephalopathy: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed immune checkpoint inhibitors (ICIs) for progressive multifocal leukoencephalopathy (PML), pooling reports involving 186 patients from 52 articles.

Neurol SciNov 4, 2026Read summary
Clinical ResearchRheumatology

Validity of the 2023 ACR/EULAR APS classification criteria for paediatric primary APS: inputs from a systematic literature review.

This systematic literature review and individual participant data-style random-effects meta-analysis assessed the 2023 ACR/EULAR antiphospholipid syndrome (APS) classification criteria in children with primary APS.

Rheumatology (Oxford)Nov 4, 2026Read summary
Clinical ResearchPediatricsOpen access

Motivation in adolescents and caretakers undergoing a weight management program - longitudinal data from the cluster-randomized, motivation-focused STARKIDS trial.

This secondary analysis of the cluster-randomized STARKIDS trial compared motivational changes among adolescents with overweight or obesity and their caretakers in a motivation-focused weight management program versus…

BMC MedNov 4, 2026Read summary
Clinical ResearchGeneral Surgery

Negative pressure incisional wound therapy for high-risk ventral hernia repair: a randomized controlled trial and meta-analysis.

This multicentre randomized controlled trial compared prophylactic negative pressure wound therapy (NPWT) with sterile dressings in adults with at least one risk factor for surgical-site complications undergoing ventral…

Can J SurgNov 4, 2026Read summary

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