Exceptional Thyroid Recurrence of Solitary Bone Plasmacytoma Detected by 18 F-FDG PET/CT.

Clin Nucl MedOct 20, 2026 (epub)
Case ReportNuclear MedicineEndocrinologyHematologyPathology (Anatomic & Clinical)

Jean-Michel Leclere, Jean-Christophe Leclere, Alexis Chambost et al.

✦ AI-curated · Sources linked

Case in brief

A 70-year-old man previously treated with radiotherapy for solitary bone plasmacytoma of the left hemipelvis underwent 18 F-FDG PET/CT follow-up. Imaging showed focal hypermetabolism in the right thyroid lobe without other abnormalities. Ultrasound classified the nodule as EU-TIRADS 5, while cytology was indeterminate (Bethesda III). Core biopsy established thyroid plasmacytoma, identifying an extramedullary recurrence at a distant site.

What made this case unusual

The recurrence involved the thyroid, an exceedingly rare site of involvement by solitary bone plasmacytoma, rather than presenting as progression to multiple myeloma.

Diagnostic / clinical pearl

In a patient with prior plasmacytoma, a suspicious thyroid lesion may represent extramedullary relapse; indeterminate cytology may require core biopsy for diagnosis.

Why it matters

The case illustrates how 18 F-FDG PET/CT can detect an otherwise unsuspected thyroid focus during follow-up, while tissue confirmation establishes its nature.

Source

PubMed · PMID 42912544

Published in Clin Nucl Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

ShareTelegramLinkedIn

AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

More in Nuclear Medicine

Clinical ResearchPreventive Medicine / Public Health

2025 National Guidelines on the Mediterranean Diet: Executive Summary of a Joint Report by Italian Scientific Societies and the National Institute of Health Task Force on Clinical Practice Guidelines.

This systematic review and practice guideline, developed by a multidisciplinary panel using NUTRIGRADE, assessed Mediterranean diet evidence across nine health domains and one economic domain.

Nutr RevNov 12, 2026Read summary
Clinical ResearchOrthopedic Surgery

Prevention of Venous Thromboembolism after Total Hip or Knee Replacement.

This multicenter randomized comparative-effectiveness noninferiority trial compared 30 days of aspirin, warfarin, or rivaroxaban for VTE prophylaxis after elective total hip or knee arthroplasty.

N Engl J MedNov 12, 2026Read summary
Clinical ResearchAnesthesiology

Effect of discontinuing antihypertensives on perioperative hypotension in older patients before non-cardiac surgery: multicentre, randomised, double blind, controlled trial.

This multicentre, randomised, double blind, placebo controlled trial assessed whether withholding ACE inhibitors or ARBs on the morning of surgery reduces perioperative hypotension in older adults undergoing non-cardiac…

BMJNov 11, 2026Read summary

Want this personalized?

Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.

  • Your specialties
  • Your filters and thresholds
  • Clinical Research + Case Reports, tuned separately
  • Automatic weekly delivery
  • Audio and text
Create my personalized digestSee plans

Prefer listening? Personalized audio digests are available with Pro.

Stay updated for free

Get the 3 most interesting publications in one specialty each week.

Weekly email. Unsubscribe anytime.