Important medical research and remarkable case reports worth knowing.
Selected from high-relevance medical literature published in the last 14 days.
This multicenter randomized comparative-effectiveness noninferiority trial compared 30 days of aspirin, warfarin, or rivaroxaban for VTE prophylaxis after elective total hip or knee arthroplasty.
Why it matters
VTE prophylaxis after hip or knee replacement requires balancing prevention of symptomatic thromboembolism against bleeding and other safety events.
This systematic review and random-effects meta-analysis compared apixaban with rivaroxaban for acute venous thromboembolism in adults.
This open-label, multicentre, randomised phase 3 trial compared decitabine plus busulfan-cyclophosphamide (DAC-BuCy) with BuCy conditioning before allogeneic HSCT in 130 patients aged 14–65 years with KMT2A-rearranged…
The multicentre randomised UK NCRI AML18 trial evaluated quizartinib after intensive chemotherapy, with or without maintenance, in patients older than 60 years with newly diagnosed AML or high-risk myelodysplastic…
This systematic review and meta-analysis assessed randomized trials of tranexamic acid (TXA) versus placebo or standard care for uterine bleeding in women of reproductive age.
This systematic review and meta-analysis compared direct oral anticoagulants (DOACs) with low molecular weight heparin (LMWH) for venous thromboembolism prophylaxis after elective total hip arthroplasty.
This systematic review and single-arm meta-analysis assessed the efficacy and safety of cladribine, idarubicin, and cytarabine (CIA) for acute myeloid leukemia (AML), separating newly diagnosed (ND) from…
This systematic review examined exercise-based physiological prehabilitation in adults with multiple myeloma or lymphoma before cellular or immune-based therapy.
This prospective, randomized phase 1/2 trial evaluated Evomela dose and infusion schedule in 60 patients with newly diagnosed multiple myeloma undergoing autologous stem cell transplantation.
This randomized controlled trial compared 8 weeks of extremely low-volume, plyometric-based high-intensity interval training (HIIT) plus oral iron with iron supplementation alone in young women aged 18–25 years with…
The multicentre, phase 2 randomized trial EPAG-2015 evaluated eltrombopag started after induction chemotherapy in patients aged 60 years or older with newly diagnosed acute myeloid leukemia.
This analysis of the CAR T-cell collection protocol used in the phase Ib/II ACIT001/EXC002 trial examined individualized blood-volume processing for patients with relapsed or refractory non-Hodgkin lymphoma or acute…
Showing 12 of 36 publications that cleared our clinical screen in the last 14 days.
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