Guillain-Barré syndrome complicated by myocarditis and acute kidney injury after maltose-based IVIG treatment: A case report.

Int J Risk Saf MedAug 12, 2026 (epub)
Case ReportNeurologyCardiologyNephrology

Anjusha K Johnson, Joby Thomas Mammen, Mary Priya et al.

✦ AI-curated · Sources linked

Case in brief

A 41-year-old man with diabetes and acute inflammatory demyelinating polyradiculoneuropathy received maltose-based intravenous immunoglobulin (IVIG). After 75 g, he developed flu-like symptoms and acute kidney injury, followed by elevated troponin, reduced ejection fraction, and electrocardiographic changes consistent with myocarditis. IVIG was stopped early. He required intensive care and hemofiltration, then recovered with supportive treatment.

What made this case unusual

The case combined myocarditis, a rare complication of Guillain-Barré syndrome, with acute kidney injury after maltose-based IVIG, an uncommon adverse effect associated with osmotic nephrosis.

Diagnostic / clinical pearl

In a patient receiving IVIG for Guillain-Barré syndrome, new renal injury and cardiac abnormalities warrant consideration of serious treatment-associated adverse effects as well as disease-related myocarditis.

Source

PubMed · PMID 42581705

Published in Int J Risk Saf Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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