Trending Now

Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

AllClinical ResearchCase Reports
FeaturedClinical ResearchCardiology

Angiotensin receptor neprilysin inhibitors and renal outcomes in patients with heart failure: a systematic review and meta-analysis.

ESC Heart FailNov 6, 2026

This systematic review and meta-analysis examined renal outcomes with angiotensin receptor neprilysin inhibitors (ARNi) versus renin-angiotensin-aldosterone system inhibitors (RAASi) alone in patients with heart…

Why it matters

Renal effects are an important consideration when selecting and monitoring heart failure therapy. These pooled trial findings suggest ARNi may be associated with fewer adverse renal outcomes than RAASi alone, while the…

Read summary

Also worth knowing

Clinical ResearchNephrologyOpen access

Transplantation of Hepatitis B Surface Antigen Positive or Viremic Kidneys: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed outcomes after transplantation of hepatitis B surface antigen-positive or viremic kidneys into non-viremic kidney transplant recipients.

Clin TransplantNov 1, 2026Read summary
Clinical ResearchNephrology

Thrombin-antithrombin complex and fibrinogen predict microangiopathic acute kidney injury in patients with traumatic injuries.

This secondary analysis of a single-center randomized controlled trial examined whether early coagulation and fibrinolysis biomarkers were associated with acute kidney injury (AKI) in adults with severe traumatic…

Blood AdvNov 12, 2026Read summary
Clinical ResearchNephrology

Association of Helicobacter pylori eradication with proteinuria reduction and kidney outcomes: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed whether Helicobacter pylori eradication is associated with renal benefits in people with kidney disease or proteinuria.

J NephrolOct 30, 2026Read summary
Clinical ResearchCardiology

Oral Potassium Supplementation Lowers Clinic Blood Pressure in Untreated Primary Hypertension-Systematic Review and Meta-Analysis of Randomized Trials.

This systematic review and meta-analysis assessed oral potassium supplementation versus placebo, sodium chloride, or no treatment in adults with untreated primary hypertension.

J Am Heart AssocOct 30, 2026Read summary
Clinical ResearchCardiology

Sex differences in cardiovascular-kidney-metabolic syndrome: the FINE-HEART pooled analysis.

This prespecified pooled analysis combined participant-level data from three trials involving people with chronic kidney disease and type 2 diabetes or heart failure with mildly reduced or preserved ejection fraction.

Eur Heart JNov 10, 2026Read summary
Clinical ResearchNephrology

Effect of Kunxian capsule, a novel Tripterygium wilfordii preparation, on reducing proteinuria and slowing renal function decline in diabetic kidney disease: a 48-week randomized controlled trial.

This 48-week randomized controlled trial assigned 80 patients with diabetic kidney disease to irbesartan-based standard therapy with or without adjunctive Kunxian capsule.

Ren FailNov 4, 2026Read summary
Clinical ResearchNephrology

Exploratory serum renal biomarker and eGFR responses to high-protein diets during resistance versus concurrent training in resistance-trained men.

This randomized 2 × 2 factorial trial examined renal biomarkers and estimated glomerular filtration rate (eGFR) in resistance-trained men consuming 1.6 or 3.2 g·kg⁻¹·d⁻¹ of protein during 16 weeks of resistance or…

J Int Soc Sports NutrNov 3, 2026Read summary
Clinical ResearchNephrology

Role of magnesium as a protective agent in cisplatin-induced nephrotoxicity in head and neck cancer.

This randomized controlled trial evaluated intravenous magnesium sulfate for prevention of cisplatin-induced nephrotoxicity in 100 newly diagnosed patients with head and neck squamous cell carcinoma receiving concurrent…

Indian J PharmacolNov 2, 2026Read summary
Clinical ResearchNephrologyOpen access

Effects of a Nurse-Led Multicomponent Exercise Intervention for Haemodialysis Patients With Possible or Confirmed Sarcopenia: A Cluster Randomised Trial.

This cluster randomised trial evaluated a 12-week nurse-led multicomponent exercise programme in haemodialysis patients with possible or confirmed sarcopenia.

Nurs OpenNov 1, 2026Read summary
Clinical ResearchCardiology

Effectiveness of nurse-led hypertension interventions on retention, adherence, and blood pressure control among adults in low- and middle-income countries: A systematic review.

This systematic review assessed nurse-led hypertension interventions in primary care among adults in low- and middle-income countries, examining retention, medication adherence, and blood pressure.

PLoS OneNov 5, 2026Read summary
Clinical ResearchNephrology

Risk factors for cognitive impairment in patients undergoing hemodialysis: an umbrella review and meta-analysis.

This umbrella review and meta-analysis examined factors associated with cognitive impairment and cognitive frailty in adults receiving maintenance hemodialysis. It included five meta-analyses covering 97 associations.

Ren FailNov 3, 2026Read summary

Showing 12 of 40 publications that cleared our clinical screen in the last 14 days.

Looking for an earlier article?Everything that has appeared in Trending is in the archive.

Stay updated for free

Get the 3 most interesting publications in one specialty each week.

Weekly email. Unsubscribe anytime.

Want this personalized?

Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.

  • Your specialties
  • Your filters and thresholds
  • Clinical Research + Case Reports, tuned separately
  • Automatic weekly delivery
  • Audio and text
Create my personalized digestSee plans

Prefer listening? Personalized audio digests are available with Pro.