Goal-directed perfusion strategy in urgent repair of Post-Myocardial infarction left ventricular free wall rupture: A case report.

PerfusionMay 23, 2026 (epub)

Somya Jain, Ram Chandra Sherawat, Dilshad Akhtar

✦ AI-curated · Sources linked

Case in brief

A 45-year-old woman presented with acute anterior ST-elevation myocardial infarction complicated by left ventricular free wall rupture and cardiogenic shock; her preoperative lactate was 11.1 mmol/L. She underwent emergency surgical repair with concomitant coronary artery bypass grafting on cardiopulmonary bypass. Perfusion was guided by physiologic targets, including indexed pump flow of 2.2–2.4 L/min/m² and indexed oxygen delivery near 300 mL/min/m², with mild hypothermia to reduce metabolic demand. Lactate clearance and hemodynamic stabilization followed.

What made this case unusual

The report describes goal-directed, physiology-based perfusion during urgent repair of post-infarction free wall rupture, a catastrophic presentation with profound oxygen debt.

Diagnostic / clinical pearl

In this case, perfusion targets included mixed venous oxygen saturation above 80% and indexed oxygen delivery near 300 mL/min/m²; monitoring these alongside lactate supported assessment of oxygen delivery and stabilization.

Source

Published in Perfusion. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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