Trending Now

Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

AllClinical ResearchCase Reports
FeaturedClinical ResearchAnesthesiology

Effect of discontinuing antihypertensives on perioperative hypotension in older patients before non-cardiac surgery: multicentre, randomised, double blind, controlled trial.

BMJNov 11, 2026

This multicentre, randomised, double blind, placebo controlled trial assessed whether withholding ACE inhibitors or ARBs on the morning of surgery reduces perioperative hypotension in older adults undergoing non-cardiac…

Why it matters

Perioperative hypotension and vasopressor use were less frequent when older patients omitted their ACE inhibitor or ARB on the morning of surgery.

Read summary

Also worth knowing

Clinical ResearchAnesthesiology

Thoracic epidural versus paravertebral blockade for reducing chronic post-thoracotomy pain (TOPIC-2): open label, parallel group, superiority, multicentre, randomised controlled trial.

This open-label, multicentre, parallel-group superiority randomised trial compared perioperative paravertebral blockade with thoracic epidural in adults undergoing thoracotomy at 15 UK centres.

BMJNov 5, 2026Read summary
Clinical ResearchAnesthesiology

Discontinuation of renin-angiotensin system inhibitors before non-cardiac surgery: a meta-analysis.

This systematic review and meta-analysis of five randomized controlled trials compared discontinuation with continuation of renin-angiotensin system inhibitors before non-cardiac, non-vascular surgery.

Eur Heart JNov 6, 2026Read summary
Clinical ResearchAnesthesiology

Effects of opioid-free and opioid-sparing anesthesia on postoperative delirium: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed opioid-free and opioid-sparing anesthesia for preventing postoperative delirium (POD) in adult surgical patients.

Medicine (Baltimore)Nov 6, 2026Read summary
Clinical ResearchPulmonologyOpen access

The Association Between Chronic Obstructive Pulmonary Disease and Postoperative Delirium: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined whether chronic obstructive pulmonary disease (COPD) is associated with postoperative delirium (POD) in surgical patients.

Int J Chron Obstruct Pulmon DisNov 4, 2026Read summary
Clinical ResearchPulmonologyOpen access

Airway Pressure Release Ventilation Versus Conventional Ventilation in Adults With or at Risk for Acute Respiratory Distress Syndrome: A Systematic Review and Meta-Analysis of Randomized Trials.

This systematic review and meta-analysis of randomized trials compared airway pressure release ventilation (APRV) with conventional invasive ventilation in adults with ARDS, acute lung injury, or conditions placing them…

LungOct 31, 2026Read summary
Clinical ResearchNeurology

Cutaneous Silent Period-Based Comparison of Dorsal Root Ganglion Pulsed Radiofrequency and Transforaminal Epidural Steroid Injection in Lumbar Radicular Pain: A Randomized Controlled Trial.

This prospective, single-blind randomized controlled trial compared dorsal root ganglion pulsed radiofrequency (DRG-PRF) with transforaminal epidural steroid injection (TFESI) in 36 patients with chronic unilateral…

Clin J PainNov 11, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Perioperative neurocognitive outcomes after robot-assisted pelvic surgery: a systematic review and meta-analysis of reported proportions, comparative risk and prognostic factors.

This systematic review and meta-analysis examined delirium and cognitive decline after robot-assisted pelvic surgery in adults, including reported proportions, comparative risk, and prognostic factors.

J Robot SurgNov 11, 2026Read summary
Clinical ResearchAnesthesiology

Oliceridine vs Sufentanil Combined With Ondansetron for Postoperative Nausea and Vomiting and QTc Interval in Hysteroscopic Surgery: A Prospective Randomized Controlled Study.

This prospective, randomized, double-blind controlled study compared oliceridine plus ondansetron with sufentanil plus ondansetron in 62 patients undergoing non-intubated hysteroscopic surgery under general anesthesia.

Med Sci MonitNov 10, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

The unseen risk: a systematic review of the incidence, management, and outcomes of the trigeminocardiac reflex in skull-base surgery.

This PRISMA-guided systematic review synthesized reports of intraoperative trigeminocardiac reflex (TCR) during skull-base and adjacent neurosurgical procedures.

Neurosurg RevNov 11, 2026Read summary
Case ReportAnesthesiologyOpen access

Esketamine-Based Versus Sevoflurane-Based Anesthesia with Dexmedetomidine for Emergence Agitation in Pediatric Corneal Suture Removal: A Randomised Controlled Trial.

Corneal suture removal, particularly microsurgery requiring complete immobility, demands adequate anesthetic depth while ensuring rapid recovery.

Drug Des Devel TherNov 6, 2026Read case
Clinical ResearchOrthopedic SurgeryOpen access

Acupuncture after surgery of soft tissue tumors of the extremities: postoperative pain and feasibility: a prospective trial.

This prospective, single-arm, single-centre pilot study assessed acupuncture feasibility and postoperative pain after extremity soft tissue tumor resection in 25 patients.

Langenbecks Arch SurgNov 10, 2026Read summary

Showing 12 of 35 publications that cleared our clinical screen in the last 14 days.

Looking for an earlier article?Everything that has appeared in Trending is in the archive.

Stay updated for free

Get the 3 most interesting publications in one specialty each week.

Weekly email. Unsubscribe anytime.

Want this personalized?

Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.

  • Your specialties
  • Your filters and thresholds
  • Clinical Research + Case Reports, tuned separately
  • Automatic weekly delivery
  • Audio and text
Create my personalized digestSee plans

Prefer listening? Personalized audio digests are available with Pro.