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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

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FeaturedClinical ResearchAnesthesiology

Thoracic epidural versus paravertebral blockade for reducing chronic post-thoracotomy pain (TOPIC-2): open label, parallel group, superiority, multicentre, randomised controlled trial.

BMJNov 5, 2026

This open-label, multicentre, parallel-group superiority randomised trial compared perioperative paravertebral blockade with thoracic epidural in adults undergoing thoracotomy at 15 UK centres.

Why it matters

The trial addresses whether the choice of regional analgesia for thoracotomy affects persistent pain as well as immediate postoperative outcomes.

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Also worth knowing

Clinical ResearchCardiology

Micro-axial flow pump vs veno-arterial extracorporeal membrane oxygenation for high-risk percutaneous coronary interventions: a randomized trial.

This prospective, multicentre, randomised, open-label non-inferiority trial compared prophylactic SynFlow 3.0 micro-axial flow pump support with VA-ECMO during non-emergent high-risk PCI in patients with complex…

Eur Heart JNov 10, 2026Read summary
Clinical ResearchCardiology

Safety and efficacy of cerebral embolic protection devices during TAVI: a meta-analysis and sequence analysis of trials.

This systematic review and meta-analysis of randomized trials assessed cerebral embolic protection (CEP) devices during transcatheter aortic valve implantation (TAVI).

Arq NeuropsiquiatrNov 6, 2026Read summary
Clinical ResearchCardiology

Clinical outcomes in various coronary artery bypass grafting techniques: A systematic review and network meta-analysis.

This systematic review and frequentist network meta-analysis compared conventional, minimally invasive, and robotic coronary artery bypass grafting (CABG), including nine sub-techniques, using observational studies and…

PLoS OneNov 5, 2026Read summary
Clinical ResearchCardiothoracic Surgery

Multivessel Versus Single-Vessel Coronary Endarterectomy as an Adjunct to Coronary Artery Bypass Grafting: A Meta-Analysis of Short-Term Outcomes and Implications for Target-Vessel Selection.

This meta-analysis compared short-term outcomes after single-vessel versus multivessel coronary endarterectomy (CE) performed with coronary artery bypass grafting (CABG), using studies that reported both groups within…

Interdiscip Cardiovasc Thorac SurgNov 3, 2026Read summary
Clinical ResearchCardiothoracic Surgery

Autologous Blood Pleurodesis for Postoperative Air Leakage Following Video-Assisted Thoracoscopic Surgery-A Randomized Controlled Trial.

This multicentre randomised controlled trial assessed early autologous blood pleurodesis (ABP) for postoperative air leakage after elective video-assisted thoracoscopic surgery.

Eur J Cardiothorac SurgNov 2, 2026Read summary
Clinical ResearchCardiothoracic SurgeryOpen access

Single-port robotic thoracic surgery: a systematic review and meta-analysis of comparative outcomes versus multiport robotic surgery and uniportal VATS.

This systematic review and meta-analysis compared single-port robotic-assisted thoracic surgery (SP-RATS) with multiport robotic surgery (MP-RATS) and uniportal video-assisted thoracoscopic surgery (uVATS).

J Robot SurgNov 9, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Liposomal Bupivacaine versus Ropivacaine for Rhomboid Intercostal and Subserratus Plane Blocks in Video-Assisted Thoracoscopic Surgery: A Randomised Controlled Trial.

This single-centre randomised controlled trial compared liposomal bupivacaine (LB) with ropivacaine (RP) for ultrasound-guided rhomboid intercostal and subserratus plane blocks in patients undergoing video-assisted…

Drug Des Devel TherNov 4, 2026Read summary
Clinical ResearchCardiology

Incidence of Intensive Care Unit Delirium After Heart Surgery: A Feasibility Study of a Forest Environment Intervention.

This randomized feasibility study evaluated forest-environment and light-exposure interventions, compared with standard care, in adults undergoing elective cardiac surgery at a tertiary ICU in Austria.

Nurs Crit CareOct 30, 2026Read summary
Clinical ResearchCardiology

Efficacy of Stellate Ganglion Block for Preventing Postoperative Atrial Fibrillation After Cardiac Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial.

This single-center, randomized, double-blind, placebo-controlled trial assessed whether preoperative ultrasound-guided right stellate ganglion block (SGB) prevents postoperative atrial fibrillation (POAF) in patients…

J Am Heart AssocOct 30, 2026Read summary
Case ReportCardiothoracic Surgery

Alfred Kocher technique for prevention of patient-prosthesis mismatch in paediatric patients.

A 7-year-old girl requiring aortic valve replacement had a functionally unicuspid aortic valve. Although the Ross procedure is generally favored in children, an intraoperative bicuspid pulmonary valve made durable…

Multimed Man Cardiothorac SurgNov 11, 2026Read case
Case ReportAnesthesiology

Arterial-to-End-Tidal CO₂ Gradient Direction as a Differential Diagnostic Clue During Sudden Hypercapnia in Thoracoscopic Surgery with Capnothorax: A Report of 2 Cases.

Two men undergoing thoracoscopic surgery with CO₂ insufflation developed abrupt rises in end-tidal CO₂ (EtCO₂). In the first, the rise coincided with severe hypotension and bradycardia; arterial blood gas showed PaCO₂…

Am J Case RepNov 10, 2026Read case

Showing 12 of 23 publications that cleared our clinical screen in the last 14 days.

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