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189 articles
November 202612
Adrenal ganglioneuroma in an adolescent presenting as an incidentaloma: Imaging-pathology correlation and diagnostic challenges: A case report.
A previously healthy 16-year-old male had a right adrenal mass discovered incidentally on CT after a bicycle accident. CT and MRI showed a well-circumscribed lesion with progressive enhancement and no washout or…
Allan-Herndon-Dudley syndrome associated with SLC16A2 c.1384G>A (p.Gly462Arg): A family case report with retrospective molecular diagnosis in a deceased sibling.
A boy evaluated at 4.3 years had profound developmental delay, abnormal tone, dystonia, muscle atrophy, contractures, and bilateral cryptorchidism.
Time- and posture-specific management of severe supine hypertension and neurogenic orthostatic hypotension in diabetic autonomic neuropathy: A case report.
A 63-year-old man with insulin-treated type 2 diabetes and hypertension developed worsening orthostatic dizziness and recurrent syncope after antihypertensive intensification, including a rib fracture and loss of…
Vitamin D receptor activator-associated calcium-alkali syndrome-like phenotype without calcium supplementation: a case series of seven patients.
A retrospective series identified seven elderly women receiving vitamin D receptor activators who developed hypercalcemia, bicarbonate of at least 26 mmol/L, and acute kidney injury, meeting the study’s operational…
Erdheim-Chester disease: a diagnostic dilemma - a report of four cases.
Four adults aged 27–40 years presented with neurological Erdheim-Chester disease (ECD), with manifestations including cerebellar ataxia, dysarthria, tremor, visual deterioration, and headache.
Severe Atherogenic Dyslipidemia in Ataxia-Telangiectasia Despite Cachexia: Mechanistic Insights into Mitochondrial Dysfunction.
A 25-year-old woman with genetically confirmed ataxia-telangiectasia and extreme underweight (body mass index 12.5 kg/m²) developed severe mixed atherogenic dyslipidemia despite modest dietary fat intake and no…
Clopidogrel-induced insulin autoimmune syndrome: A case report and analysis of clinical characteristics in Chinese patients.
A 69-year-old Chinese man developed hypoglycemic symptoms and was diagnosed with insulin autoimmune syndrome after starting clopidogrel.
Orthoplastic Limb Salvage Using Transtibial Transport and Free-Flap Reconstruction in Patients With Diabetes-Related Chronic Limb-Threatening Ischemia.
A 56-year-old man with poorly controlled diabetes and severe peripheral arterial disease developed a chronic foot ulcer with toe gangrene despite unsuccessful revascularization, leaving no conventional revascularization…
Tirzepatide-associated severe euvolemic hyponatremia with syndrome of inappropriate antidiuretic hormone secretion-compatible biochemical features.
A woman with type 2 diabetes and morbid obesity, taking regular insulin and chronic torsemide, developed anorexia, weakness, and drowsiness 10 days after receiving tirzepatide.
Proton-pump inhibitor-induced severe hypomagnesemia presenting with seizure and functional hypoparathyroidism: A diagnostic challenge in long-term acid suppression therapy.
A 68-year-old man taking omeprazole 40 mg/day for 8 years presented with a generalized tonic-clonic seizure and neuromuscular irritability.
Expanding the role of ivabradine in thyrotoxic crisis: a case report and Insights from the Literature.
A 39-year-old woman with alemtuzumab-induced Graves’ disease developed thyroid storm with persistent sinus tachycardia despite high-dose propranolol.
A Neonate With Excessive Weight Loss and Electrolyte Abnormalities.
A 7-day-old girl was hospitalized for excessive weight loss. Initial testing showed hyponatremia and hyperkalemia, prompting evaluation for endocrine, renal, and metabolic causes.
October 202612
Hypothalamic Neurochemical and Microglial Suppression in Long-Standing Human Hibernation-Like Syndrome.
A 57-year-old woman had a more than 30-year history of winter-associated hypothermia, neuroendocrine instability, psychomotor suppression and circannual rhythmicity.
Vertebral fractures in a young woman: the impact of hypogonadism, glucocorticoids, and chronic disease.
A premenopausal woman developed painful vertebral fractures while receiving prednisolone for newly diagnosed systemic lupus erythematosus.
Parathyroid Hormone-related Peptide Is a Better Indicator of Cancer Treatment Efficacy Than Serum Calcium.
A 66-year-old woman with extensive cutaneous squamous cell carcinoma of the scalp, unsuitable for primary surgical removal, received cemiplimab.
HHV-6 Encephalitis Presenting With Severe SIADH and CO₂ Narcosis in Non-Transplant Smoldering Adult T-Cell Leukemia/Lymphoma.
A 55-year-old woman with smoldering adult T-cell leukemia/lymphoma (ATLL), treated with systemic corticosteroids for suspected HTLV-1-associated uveitis, was admitted with pulmonary infection.
Delayed diagnosis of MEN1 after kidney transplantation: unrecognized pre-transplant features and implications for clinical practice.
A 68-year-old man with end-stage renal disease underwent living-donor kidney transplantation and had persistent hypercalcemia afterward.
A case report of thyroid sarcomatoid carcinoma.
A 65-year-old man presented with fever and left-sided neck pain; examination found a hard mass in the left thyroid lobe. Ultrasound showed a hypoechoic nodule with an anterior-posterior-to-transverse diameter ratio >1…
When Insulin Must Wait: The Role of Renal Replacement Therapy in Refractory Hypokalemia During Severe Diabetic Ketoacidosis.
A 37-year-old man presented with abdominal pain, progressive dyspnea, drowsiness, and Kussmaul respirations. Testing showed severe diabetic ketoacidosis (DKA), acute kidney injury, and severe hypokalemia.
Occult Abdominal Para-Aortic Ectopic Insulinoma Localized by 18 F-NOTA-Exendin-4 PET/CT.
A 68-year-old woman with a 10-year history of recurrent hypoglycemic syncope had confirmed endogenous hyperinsulinemia. Conventional imaging and laparoscopic exploration of the pancreas did not identify a lesion.
SPECT/CT With 99m Tc-MIBI as an Early Indicator of the Success of Radiofrequency Ablation of Parathyroid Adenomas.
A 55-year-old man with hypercalcemic primary hyperparathyroidism had a right inferior parathyroid adenoma localized by 99m Tc-MIBI SPECT/CT.
Exceptional Thyroid Recurrence of Solitary Bone Plasmacytoma Detected by 18 F-FDG PET/CT.
A 70-year-old man previously treated with radiotherapy for solitary bone plasmacytoma of the left hemipelvis underwent 18 F-FDG PET/CT follow-up.
Pacak-Zhuang syndrome with EPAS1 p.Pro531Leu somatic variant: one case report and literature review.
A 4-year-old girl presented with recurrent hypertension, polycythemia and renal hilar masses. Imaging, biochemical testing and genetic analysis of paraffin-embedded tissue confirmed Pacak-Zhuang syndrome with a somatic…
Approach to the patient with APS-1/APECED.
This article presents five cases of autoimmune polyendocrine syndrome type 1 (APS-1/APECED), a disorder caused by impaired immune tolerance and typically associated with biallelic AIRE variants.
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