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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

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Case ReportOrthopedic SurgeryOpen access

Effect of Intravenous Acetaminophen on Preemptive Multimodal Analgesia for Pediatric Osteotomy Correction Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial.

Children undergoing Osteotomy correction surgery can experience substantial postoperative pain and frequently require opioids.

Drug Des Devel TherOct 30, 2026Read case
Case ReportAnesthesiology

Arterial-to-End-Tidal CO₂ Gradient Direction as a Differential Diagnostic Clue During Sudden Hypercapnia in Thoracoscopic Surgery with Capnothorax: A Report of 2 Cases.

Two men undergoing thoracoscopic surgery with CO₂ insufflation developed abrupt rises in end-tidal CO₂ (EtCO₂). In the first, the rise coincided with severe hypotension and bradycardia; arterial blood gas showed PaCO₂…

Am J Case RepNov 10, 2026Read case
Case ReportOncology (Medical)

Dexmedetomidine with transition to oral clonidine for stabilization of refractory agitation: A case report.

A 45-year-old man with metastatic medullary thyroid carcinoma was admitted to a palliative care unit with severe opioid-refractory pain, delirium, and agitation that prevented palliative radiation.

Palliat Support CareNov 5, 2026Read case
Case ReportAnesthesiology

Stellate Ganglion Block for Treatment of Refractory Sympathetic Storm in Severe Tetanus: A Case Report.

A 67-year-old man developed severe tetanus after a bamboo-skewer puncture wound to his left middle finger; the foreign body remained embedded for 3 days before he removed it himself, and he received no systematic…

Am J Case RepNov 5, 2026Read case
Case ReportAnesthesiology

Adjunctive Imaging to Confirm Ultrasound-Guided Paravertebral Catheter Tip Position in Children: Case Reports.

The report describes children receiving ultrasound-guided paravertebral catheters for perioperative analgesia during thoracic procedures.

A A PractNov 4, 2026Read case
Case ReportAnesthesiology

Oral administration of parenteral S-ketamine in wound care when 'conventional' medication regimens are not sufficient: a case series.

A case series described four patients whose pain during wound care was not adequately controlled by conventional medication regimens.

J Wound CareNov 2, 2026Read case
Case ReportAnesthesiologyOpen access

Pump-Predicted Ciprofol Ce50 for Suppressing the Cardiovascular Response to Tracheal Intubation During Fixed Sufentanil-Esketamine Induction: An Age-Stratified Dixon Up-and-Down Study.

To estimate the ciprofol pump-predicted effect-site target concentration associated with a 50% probability of suppressing the cardiovascular response to tracheal intubation (Ce50) during fixed sufentanil-esketamine…

Drug Des Devel TherNov 1, 2026Read case
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