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2000 articles
October 202624
From metastatic disease to no evidence of disease after conversion liver surgery in advanced gastric cancer with liver metastases: A case report.
A 54-year-old woman with initially unresectable, HER2-negative, pMMR-by-IHC, EBER-positive gastric cancer and synchronous liver metastases received tislelizumab-based chemotherapy, with regimen changes after suspected…
Concurrent administration of BCMA and GPRC5D CAR T cells for advanced multiple myeloma.
This phase 1 dose-escalation trial evaluated BCMA-directed CAR T-cell therapy MCARH125 alone or infused concurrently with GPRC5D-directed MCARH109 in patients with relapsed or refractory multiple myeloma.
The prognostic value of physical functioning on survival in patients with nonsmall cell lung cancer: a systematic review and meta-analysis.
This systematic review and meta-analysis examined whether objectively measured physical functioning predicts survival in adults with nonsmall cell lung cancer (NSCLC), across surgical and nonsurgical treatment groups.
Disease-free survival and overall survival after neoadjuvant immunotherapy in mismatch repair-deficient colon cancer in the Netherlands: results of the single-arm, multicentre, phase 2, NICHE-2 trial.
This single-arm, multicentre phase 2 trial assessed neoadjuvant ipilimumab plus nivolumab followed by surgery in previously untreated patients with resectable stage 2 or 3 mismatch repair-deficient colon cancer.
The role of allogeneic hematopoietic stem cell transplantation in adults with mature T-cell lymphomas.
This Cochrane systematic review and meta-analysis assessed allogeneic stem cell transplantation (alloSCT) for adults with mature T-cell lymphomas (MTCL), as first-line or salvage treatment.
Effectiveness of cardiac resynchronization therapy in cancer therapy-related cardiac dysfunction: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis assessed cardiac resynchronization therapy (CRT) outcomes in patients with cancer therapy-related cardiac dysfunction (CTRCD).
Feasibility and safety of an exercise-based prehabilitation intervention before cancer surgery: a pilot randomised controlled trial.
This single-centre pilot randomised controlled trial assessed the feasibility and safety of supervised aerobic prehabilitation before surgery in patients with breast, colorectal, or prostate cancer.
Interventions to increase participation in lung cancer screening programmes: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed interventions to improve informed choice and participation in low-dose CT lung cancer screening.
METASTATIC UROTHELIAL CARCINOMA OF THE BLADDER TO THE RETINA: A CLINICOPATHOLOGIC CORRELATION AND REVIEW OF THE LITERATURE.
A patient with urothelial carcinoma of the bladder had a large yellow-white lesion in the superotemporal retina of the left eye.
Combination of oral fluoropyrimidines and EGFR-directed antibodies in frail patients with metastatic colorectal cancer: a systematic review.
This systematic review assessed phase II and III evidence for oral fluoropyrimidines combined with EGFR-directed antibodies in patients with RAS wild-type metastatic colorectal cancer, including those considered unfit…
A Favorable Partial Response in Patients With Glioblastoma Multiforme Following Combined [ 177 Lu]Lu-FAP-2286 and Chemotherapy.
A 64-year-old woman with IDH-wild-type, WHO grade IV glioblastoma underwent [68Ga]Ga-FAP-2286 PET/CT, which detected active tumor recurrence before definitive radiologic evidence of progression.
A Consistently Elevated Pineal Gland Uptake of 18 F-MFBG as a Physiological Normal Variant.
A 3-year-old girl with high-risk neuroblastoma underwent 18F-MFBG PET/CT to assess treatment response. Imaging showed focal pineal gland uptake, also present on concurrent 68Ga-DOTATATE PET/CT.
FDG Uptake Extending From the Dorsal Root Ganglion to the Sciatic Nerve After Herpes Zoster.
A woman in her 50s receiving paclitaxel, carboplatin, and pembrolizumab for recurrent cervical cancer developed herpes zoster and was treated with antivirals.
Meta-analysis of 990 EBV genomes identifies EBER2 SNP7048 and its interaction with HLA-A*11:01 driving nasopharyngeal carcinoma risk.
This meta-analysis examined whether EBV genetic variation and host genetics are associated with nasopharyngeal carcinoma (NPC) across endemic populations in Singapore, Hong Kong, and China’s Guangdong and Guangxi…
Not Every PSMA-Expressing Bone Lesion Is Prostate Cancer: Incidental Detection of Metastatic Differentiated Thyroid Carcinoma on Staging 68 Ga-PSMA-11 PET/CT.
A patient with newly diagnosed high-risk prostate adenocarcinoma underwent staging 68Ga-PSMA-11 PET/CT. Alongside the primary prostatic lesion, PSMA-expressing foci were seen in the sternum and right thyroid lobe.
Rectosigmoid Intussusception Secondary to Colorectal Carcinoma Imaged With 18 F-FDG PET/CT.
An 80-year-old man with rectosigmoid adenocarcinoma underwent 18F-FDG PET/CT. The study showed rectosigmoid intussusception, with a target sign visible on both PET and CT, as well as synchronous FDG-avid lung metastases.
A Tale of 3 Tracers: Contrasting Uptake Patterns of 18 F-FDG, 68 Ga-DOTATATE, and 18 F-MFBG in a Pediatric Neuroblastoma Patient.
A 5-year-old boy underwent 18 F-FDG PET/CT before neuroblastoma was confirmed histologically. Imaging showed a metabolically active left adrenal primary tumor and liver metastases.
Entinostat plus exemestane for hormone receptor-positive advanced breast cancer: long-term overall survival results from the EOC103A3101 randomized controlled trial.
This randomized controlled trial assessed long-term overall survival with entinostat plus exemestane versus placebo plus exemestane in 354 patients with hormone receptor-positive, HER2-negative advanced breast cancer…
Challenges of Conducting a Feasibility Pilot Randomized Controlled Trial During COVID-19 Restrictions: Rivaroxaban Versus Acetyl Salicylic Acid in Patients with Multiple Myeloma on Lenalidomide-Based Therapy (RithMM).
This multicentre pilot randomised controlled trial assessed whether a full-scale comparison of rivaroxaban and acetylsalicylic acid for thromboprophylaxis was feasible in patients with multiple myeloma receiving…
99m Tc-FAPI-46 SPECT/CT in Ewing Sarcoma : Findings in Diverse Metastatic Presentations.
Two young men with advanced metastatic Ewing sarcoma underwent 99mTc-FAPI-46 SPECT/CT. In one, imaging showed uptake in multiple osteoblastic skeletal metastases and pleural lesions.
Detecting Isolated Multifocal Leptomeningeal Metastases With 18F-MFBG PET/CT in a Pediatric Patient With High-risk Neuroblastoma.
A 2-year-old girl with high-risk neuroblastoma had abdominal primary disease and multiple metastases on baseline 18F-MFBG PET/CT. After induction therapy, restaging showed no abnormal tracer uptake.
Five-Year Persistent 18 F-FAPI-74 Uptake in Radiation-induced Hepatic Fibrosis Following Proton Beam Therapy for Hepatocellular Carcinoma.
A 79-year-old man treated with proton beam therapy for hepatocellular carcinoma had stable T2-weighted hyperintensity in the irradiated liver region on follow-up MRI, without enlargement or mass formation.
Immune Checkpoint Inhibitor Myocarditis on FDG PET/CT and Cardiac MR.
A 54-year-old man with stage 4 squamous cell carcinoma receiving pembrolizumab developed symptoms of heart failure. FDG PET/CT showed new cardiomegaly and intense myocardial uptake, while concurrent contrast-enhanced…
Vertebral Hemangioma Sparing in a 99m Tc-PSMA Superscan.
A 60-year-old man with biopsy-proven prostate adenocarcinoma underwent 99mTc-PSMA scintigraphy while being evaluated for potential 177Lu-PSMA radioligand therapy.
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