FDG Uptake Extending From the Dorsal Root Ganglion to the Sciatic Nerve After Herpes Zoster.

Clin Nucl MedOct 20, 2026 (epub)
Case ReportNuclear MedicineOncology (Medical)Infectious Diseases

Keiko Matsunaga, Miho Kitai, Nobuo Kashiwagi

✦ AI-curated · Sources linked

Case in brief

A woman in her 50s receiving paclitaxel, carboplatin, and pembrolizumab for recurrent cervical cancer developed herpes zoster and was treated with antivirals. FDG PET/CT performed 22 days after symptom onset, after the skin lesions had crusted, showed continuous uptake from the left L5 dorsal root ganglion along the sciatic nerve, consistent with ganglioneuritis. The report highlights that this post-zoster imaging pattern can complicate interpretation in a patient with cancer receiving chemoimmunotherapy.

What made this case unusual

The FDG uptake extended continuously from a dorsal root ganglion into a peripheral nerve after herpes zoster, a pattern the authors describe as the first reported PET finding of this extent.

Diagnostic / clinical pearl

In a patient receiving chemoimmunotherapy, nerve uptake on FDG PET/CT after zoster may reflect post-zoster ganglioneuritis rather than immune-related neuritis or perineural tumor spread.

Source

PubMed · PMID 42912576

Published in Clin Nucl Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

ShareTelegramLinkedIn

AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

More in Nuclear Medicine

Clinical ResearchPreventive Medicine / Public Health

2025 National Guidelines on the Mediterranean Diet: Executive Summary of a Joint Report by Italian Scientific Societies and the National Institute of Health Task Force on Clinical Practice Guidelines.

This systematic review and practice guideline, developed by a multidisciplinary panel using NUTRIGRADE, assessed Mediterranean diet evidence across nine health domains and one economic domain.

Nutr RevNov 12, 2026Read summary
Clinical ResearchOrthopedic Surgery

Prevention of Venous Thromboembolism after Total Hip or Knee Replacement.

This multicenter randomized comparative-effectiveness noninferiority trial compared 30 days of aspirin, warfarin, or rivaroxaban for VTE prophylaxis after elective total hip or knee arthroplasty.

N Engl J MedNov 12, 2026Read summary
Clinical ResearchAnesthesiology

Effect of discontinuing antihypertensives on perioperative hypotension in older patients before non-cardiac surgery: multicentre, randomised, double blind, controlled trial.

This multicentre, randomised, double blind, placebo controlled trial assessed whether withholding ACE inhibitors or ARBs on the morning of surgery reduces perioperative hypotension in older adults undergoing non-cardiac…

BMJNov 11, 2026Read summary

Want this personalized?

Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.

  • Your specialties
  • Your filters and thresholds
  • Clinical Research + Case Reports, tuned separately
  • Automatic weekly delivery
  • Audio and text
Create my personalized digestSee plans

Prefer listening? Personalized audio digests are available with Pro.

Stay updated for free

Get the 3 most interesting publications in one specialty each week.

Weekly email. Unsubscribe anytime.