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1357 articles

November 202624

Clinical ResearchPreventive Medicine / Public Health

Development and evaluation of a subjective measurement of geographical hardness-to-reach: a survey of data collectors in a large-scale cluster randomised trial of azithromycin mass drug administration.

This sub-study within a large-scale cluster-randomised trial of azithromycin mass drug administration in Mali developed and evaluated a 14-item survey of village accessibility, completed by 25 data collectors.

J Glob HealthNov 6, 2026Read summary
Clinical ResearchGeriatricsOpen access

Testing the EQ-HWB-9 with seven-day versus today recall periods in dementia: variability and recall adherence under health fluctuations.

This mixed-methods randomized study compared “7-day” and “today” EQ-HWB-9 recall periods in people living with dementia and caregiver dyads recruited from German primary care.

Qual Life ResNov 6, 2026Read summary
Clinical ResearchCardiology

The relationship between sirtuin1 gene polymorphism and coronary heart disease: Systematic review and meta-analysis.

This systematic review and meta-analysis examined associations between four SIRT1 gene polymorphisms and coronary heart disease (CHD), drawing on 9 articles with 1,839 cases and 1,937 controls.

Medicine (Baltimore)Nov 6, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Effects of intradermal lymphocyte therapy in patients with recurrent pregnancy loss: secondary analysis of a randomized controlled trial investigating purinergic signaling, inflammation, and cellular energy status.

This secondary analysis of a randomized controlled trial examined low-dose intradermal lymphocyte therapy (ILT) in 100 patients with recurrent pregnancy loss (RPL), comparing 50 treated patients with 50 receiving…

Mol Biol RepNov 6, 2026Read summary
Clinical ResearchNeurologyOpen access

Intra-arterial tenecteplase for acute basilar artery occlusion with sufficient recanalization after thrombectomy: the INSIST-IT randomized clinical trial.

The INSIST-IT multicentre, prospective, randomised trial assessed adjunctive intra-arterial tenecteplase after successful endovascular reperfusion in patients with acute basilar artery occlusion treated within 24 hours…

Nat CommunNov 6, 2026Read summary
Clinical ResearchUrology

Peptides for male sexual dysfunction: a systematic review of emerging evidence.

This PRISMA-guided systematic review assessed human studies of peptide-based therapies for male sexual function, reproductive hormones, and semen parameters.

J Sex MedNov 6, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Optimal duration of levetiracetam prophylaxis following supratentorial tumor resection: a multi-study analysis.

This systematic review and meta-analysis compared short-course (≤ 9 days) with extended-course (> 9 days) levetiracetam prophylaxis in seizure-naïve patients after supratentorial tumor resection.

Neurosurg RevNov 6, 2026Read summary
Clinical ResearchNeurologyOpen access

Subsequent epilepsy surgery after SEEG-guided radiofrequency thermocoagulation: Outcomes and prognostic value of treatment response-a systematic review and meta-analysis.

This systematic review and meta-analysis assessed outcomes after resective, disconnective, or ablative epilepsy surgery in patients previously treated with SEEG-guided radiofrequency thermocoagulation (SEEG-RFTC), and…

Neurosurg RevNov 6, 2026Read summary
Clinical ResearchUrology

Efficacy of diadynamic currents versus transcutaneous electrical nerve stimulation for transcutaneous tibial nerve stimulation in subjects with overactive bladder syndrome: A double-blind randomized controlled trial.

This double-blind randomized controlled trial compared transcutaneous tibial nerve stimulation (TTNS) delivered with diadynamic currents (DDC) or transcutaneous electrical nerve stimulation (TENS) in women aged 18–80…

PLoS OneNov 6, 2026Read summary
Clinical ResearchCardiology

Angiotensin receptor neprilysin inhibitors and renal outcomes in patients with heart failure: a systematic review and meta-analysis.

This systematic review and meta-analysis examined renal outcomes with angiotensin receptor neprilysin inhibitors (ARNi) versus renin-angiotensin-aldosterone system inhibitors (RAASi) alone in patients with heart…

ESC Heart FailNov 6, 2026Read summary
Clinical ResearchAnesthesiology

Discontinuation of renin-angiotensin system inhibitors before non-cardiac surgery: a meta-analysis.

This systematic review and meta-analysis of five randomized controlled trials compared discontinuation with continuation of renin-angiotensin system inhibitors before non-cardiac, non-vascular surgery.

Eur Heart JNov 6, 2026Read summary
Clinical ResearchCardiology

Women's cardiovascular health in Aotearoa New Zealand: insights from a systematic literature review.

This systematic review synthesised research on women’s cardiovascular health in Aotearoa New Zealand, including clinical outcomes, awareness and lived experience.

N Z Med JNov 6, 2026Read summary
Clinical ResearchPediatrics

Effects of a parenting and unconditional cash transfer intervention on child development and maternal well-being in urban Bangladesh: medium-term follow-up of a cluster randomised controlled trial.

This medium-term follow-up of a cluster randomised controlled trial in Rangpur, Bangladesh, compared parenting plus unconditional cash transfers with cash transfers alone.

J Glob HealthNov 6, 2026Read summary
Clinical ResearchGeneral Surgery

Clinical characteristics, treatment, and prognosis of sexual-related rectal foreign bodies: a systematic review and meta-analysis.

This systematic review and meta-analysis examined clinical features, management, and outcomes of sexual-related rectal foreign bodies, drawing on 59 case reports, case series, and cohort studies from 22 countries, with…

J Sex MedNov 6, 2026Read summary
Clinical ResearchPediatrics

Effect of a dietary behaviour change education intervention on iron status and linear growth in children aged 6 to 59 months: a cluster-randomised controlled trial in rural Ethiopia.

This cluster-randomised controlled trial evaluated community-based Dietary Intake Behaviour Education (DIBE) among children aged 6–59 months in rural central Ethiopia.

Prim Health Care Res DevNov 6, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Effects and safety of Korean red ginseng on the clinical course of uterine leiomyoma: A double-blind randomized placebo-controlled trial.

This single-center, double-blind randomized placebo-controlled trial assessed Korean red ginseng (KRG) in premenopausal women with uterine leiomyoma managed expectantly.

Medicine (Baltimore)Nov 6, 2026Read summary
Clinical ResearchAnesthesiology

Effects of opioid-free and opioid-sparing anesthesia on postoperative delirium: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed opioid-free and opioid-sparing anesthesia for preventing postoperative delirium (POD) in adult surgical patients.

Medicine (Baltimore)Nov 6, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Pin-related complications in robotic-assisted total knee arthroplasty: a systematic review and meta-analysis of 15,874 knees.

This systematic review and meta-analysis assessed pin-related complications after primary robotic-assisted total knee arthroplasty (RA-TKA), including 37 studies and 15,874 knees.

J Robot SurgNov 6, 2026Read summary
Clinical ResearchGastroenterology

Prognostic value of anti-gp210 antibodies in primary biliary cholangitis: A Systematic review and meta-analysis.

This systematic review and meta-analysis pooled evidence from 12 records examining the prognostic significance of anti-gp210 antibodies in people with primary biliary cholangitis (PBC).

Medicine (Baltimore)Nov 6, 2026Read summary
Clinical ResearchOncology (Medical)

Comparative efficacy and safety of second- and later-line BRAF-targeted regimens in BRAF V600E-mutant metastatic colorectal cancer: A systematic review and network meta-analysis.

This systematic review and network meta-analysis compared the efficacy and safety of second- and later-line BRAF-targeted regimens in adults with BRAF V600E-mutant metastatic colorectal cancer.

Medicine (Baltimore)Nov 6, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Efficacy of ablative laser therapy for vulvar lichen sclerosus: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis assessed randomized trials of fractional ablative laser therapy in adult women with confirmed vulvar lichen sclerosus.

Lasers Med SciNov 6, 2026Read summary
Clinical ResearchCardiology

Mitral regurgitation and all-cause mortality in acute heart failure: a meta-analysis.

This meta-analysis examined the association between mitral regurgitation (MR) and all-cause mortality in acute heart failure (AHF), pooling 27 studies with 73 363 patients and an average follow-up of 1.9 years.

ESC Heart FailNov 6, 2026Read summary
Clinical ResearchUrologyOpen access

Comparative outcomes of Hugo RAS and Versius surgical systems versus da Vinci in four urological procedures: a systematic review.

This PRISMA-guided systematic review compared Hugo RAS and Versius with da Vinci in robot-assisted radical prostatectomy, partial nephrectomy, pyeloplasty, and radical cystectomy.

J Robot SurgNov 6, 2026Read summary
Clinical ResearchEndocrinology

Effects of vitamin D supplementation on vitamin D status and physical performance in football players: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed controlled intervention studies of vitamin D supplementation in association football and futsal players.

PLoS OneNov 6, 2026Read summary

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