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845 articles
October 202624
Anti-GBM/ANCA double-positive crescentic nephritis in an elderly patient presenting with heart failure-like symptoms: A case report.
A 74-year-old woman presented with progressive shortness of breath, nausea, and vomiting, initially raising concern for heart failure. Testing instead showed severe renal impairment (creatinine 1025.99 μmol/L).
Relapsed Waldenström macroglobulinemia presenting as bilateral parotid gland enlargement with multiple cystic lesions: A case report.
A 79-year-old man with Waldenström macroglobulinemia (WM), previously stable for several years after multiple courses of chemotherapy, developed bilateral parotid enlargement. Imaging showed multiple cystic lesions.
Vulvar infection caused by Histoplasma capsulatum: case report and literature review.
A 38-year-old woman with advanced HIV infection presented with a vulvar lesion suggestive of carcinoma. Histopathology, fungal culture and molecular testing confirmed vulvar infection with Histoplasma capsulatum var.
Role of Plasma Proteins in the Association Between Socioeconomic Status and Cardiovascular Disease Events: Results From Trans-Omics for Precision Medicine Cohorts.
This meta-analysis examined socioeconomic status (SES), plasma proteins, and incident coronary heart disease (CHD) and stroke in participants from three cohorts.
Unexpected finding of AA amyloidosis with novel genetic variants in the MEFV gene in patients undergoing kidney biopsy for proteinuria. A case series.
The report describes patients undergoing kidney biopsy for proteinuria in whom AA amyloidosis was identified, alongside MEFV gene variants.
From inference to proof: nanopore sequencing confirms zoonotic Neisseria Zoodegmatis peritonitis after cat bite-related contamination in a patient on automated peritoneal dialysis.
A 90-year-old patient receiving automated peritoneal dialysis developed peritonitis after a cat bite damaged the transfer set. Empirical therapy produced only a partial response, followed by relapse.
From metastatic disease to no evidence of disease after conversion liver surgery in advanced gastric cancer with liver metastases: A case report.
A 54-year-old woman with initially unresectable, HER2-negative, pMMR-by-IHC, EBER-positive gastric cancer and synchronous liver metastases received tislelizumab-based chemotherapy, with regimen changes after suspected…
Molecular-genetic mechanisms of cerebral arteriovenous malformations: A systematic review of germline, somatic and experimental evidence.
This systematic review synthesised human genetic, molecular, and experimental evidence on cerebral arteriovenous malformation (AVM) formation, clinical course, and potential therapeutic targets.
Translational applications and clinical utility of organoids in ovarian cancer: a systematic review.
This systematic review synthesized 13 studies of patient-derived organoids (PDOs) in ovarian cancer, assessing feasibility, histological fidelity, and agreement between organoid drug sensitivity and clinical outcomes.
A case of lysozyme-induced nephropathy with improved renal function following treatment for chronic myelomonocytic leukemia.
A 75-year-old man with longstanding diabetes presented with weight loss and progressive anemia and was diagnosed with chronic myelomonocytic leukemia (CMML).
Effectiveness of tocilizumab monotherapy for IgG4-related disease-like features caused by idiopathic multicentric Castleman's disease: a case-based review.
A 68-year-old woman presented with dyspnea associated with a recurrent laryngeal tumor, pulmonary consolidation, mediastinal and axillary lymphadenopathy, sclerosing mesenteritis, and retroperitoneal fibrosis.
METASTATIC UROTHELIAL CARCINOMA OF THE BLADDER TO THE RETINA: A CLINICOPATHOLOGIC CORRELATION AND REVIEW OF THE LITERATURE.
A patient with urothelial carcinoma of the bladder had a large yellow-white lesion in the superotemporal retina of the left eye.
Baseline Serum Metabolites as Predictors of Teplizumab Response in Individuals With Type 1 Diabetes.
This analysis examined whether baseline serum metabolites could predict response to teplizumab in 41 people newly diagnosed with type 1 diabetes who participated in the randomized AbATE trial.
Duplicated Appendix With Mucocele Mimicking an Appendiceal Neoplasm in a 45-Year-Old Woman: A Case Report.
A 45-year-old woman with right lower-quadrant pain and fever had CT evidence of ruptured appendicitis with a loculated peri-appendiceal abscess, which improved after percutaneous drainage and intravenous antibiotics.
Co-occurrence of aortic dissection and polycystic kidney disease: a case report.
A 19-year-old Caucasian man with no known medical history collapsed during sexual intercourse and died. Post-mortem examination found hemopericardium and aortic dissection in association with polycystic kidney disease…
Disease-free survival and overall survival after neoadjuvant immunotherapy in mismatch repair-deficient colon cancer in the Netherlands: results of the single-arm, multicentre, phase 2, NICHE-2 trial.
This single-arm, multicentre phase 2 trial assessed neoadjuvant ipilimumab plus nivolumab followed by surgery in previously untreated patients with resectable stage 2 or 3 mismatch repair-deficient colon cancer.
Primary intracranial sarcoma, DICER1-mutant: 5 cases highlighting variable clinical and molecular features.
The report describes five patients aged 6 to 40 years with primary intracranial sarcoma, DICER1-mutant, identified through methylation profiling and/or sequencing.
Ciliated hepatic foregut cyst in children and adolescents: a systematic review of clinical presentation, diagnosis, management, and outcomes.
This PRISMA 2020 systematic review descriptively synthesised case reports and case series of histopathologically confirmed ciliated hepatic foregut cysts in patients aged 19 years or younger.
The Clinical Significance of Hyperkinetic Biliary Dyskinesia on HIDA Scan: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis assessed outcomes after cholecystectomy in patients with biliary-type pain and gallbladder ejection fraction (EF) ≥80% on CCK-stimulated HIDA scans.
Chondromyxoid Fibroma of the Rib on 99m Tc-MDP SPECT/CT.
A 37-year-old woman with persistent right-sided back pain underwent ⁹⁹ᵐTc-MDP SPECT/CT, which showed a solitary focus of intense radiotracer uptake corresponding to a rib lesion.
Not Every PSMA-Expressing Bone Lesion Is Prostate Cancer: Incidental Detection of Metastatic Differentiated Thyroid Carcinoma on Staging 68 Ga-PSMA-11 PET/CT.
A patient with newly diagnosed high-risk prostate adenocarcinoma underwent staging 68Ga-PSMA-11 PET/CT. Alongside the primary prostatic lesion, PSMA-expressing foci were seen in the sternum and right thyroid lobe.
Exceptional Thyroid Recurrence of Solitary Bone Plasmacytoma Detected by 18 F-FDG PET/CT.
A 70-year-old man previously treated with radiotherapy for solitary bone plasmacytoma of the left hemipelvis underwent 18 F-FDG PET/CT follow-up.
FAPI PET/CT Outperforms MRI and FDG PET/CT in Tumor Delineation for Low-grade Nasopharyngeal Papillary Adenocarcinoma.
A 27-year-old man with a 1-year history of bloody postnasal drip had an enhancing protuberance on the roof and posterior wall of the nasopharynx on MRI.
[ 18 F]AlF-NOTA-FAPI-04 PET/CT for Incidental Detection of a Benign Phyllodes Tumor in a Patient With Prior Colon Cancer.
A 68-year-old woman with a history of colon cancer had a right breast nodule detected incidentally on routine contrast-enhanced CT, where it showed moderate enhancement.
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