Vulvar infection caused by Histoplasma capsulatum: case report and literature review.

Enferm Infecc Microbiol Clin (Engl Ed)Oct 23, 2026 (epub)
Case ReportInfectious DiseasesObstetrics & GynecologyPathology (Anatomic & Clinical)

Fátima Vioque, Montserrat Sevillano, Daniel Tena et al.

✦ AI-curated · Sources linked

Case in brief

A 38-year-old woman with advanced HIV infection presented with a vulvar lesion suggestive of carcinoma. Histopathology, fungal culture and molecular testing confirmed vulvar infection with Histoplasma capsulatum var. duboisii. She received antifungal therapy and had a favorable outcome.

What made this case unusual

The infection presented as a lesion resembling vulvar carcinoma, illustrating how genital histoplasmosis can mimic neoplastic disease.

Diagnostic / clinical pearl

In an immunocompromised patient with a suspicious vulvar lesion, include histoplasmosis in the differential and use tissue examination with microbiological and molecular testing to establish the diagnosis.

Source

PubMed · PMID 42919720

Published in Enferm Infecc Microbiol Clin (Engl Ed). This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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