Trending archive
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1320 articles
November 20267
Brain Abscesses as a Complication of Brain Hematomas in Infective Endocarditis: A Rare Case Report.
A previously healthy 26-year-old man with methicillin-sensitive Staphylococcus aureus infective endocarditis had a 24-mm parietal hematoma; angiography showed no aneurysm.
Polyneuropathy, Organomegaly, Endocrinopathy, M-Protein, and Skin Changes (POEMS) Syndrome With Characteristic Muscle Biopsy Findings and Without M-Protein.
A 63-year-old woman referred with presumed CIDP had not responded to IVIG or steroids. Her presentation included marked weight loss, papilledema, skin changes, thrombocytosis, thromboembolisms, hemi-diaphragmatic…
Anti-Contactin-1 Nodopathy Presenting With Dysphagia and Nephrotic Syndrome: Remarkable Neurological and Renal Recovery Following Early B-Cell-Targeted Therapy.
A 77-year-old man with diabetes and pre-existing heavy proteinuria developed rapidly progressive distal numbness, weakness, sensory ataxia, mild dysphagia, and functional decline.
Anatomy-specific Performance of CTA-based AI for Anterior Circulation Occlusion: Systematic Review and Meta-analysis.
This prospectively registered systematic review and diagnostic meta-analysis assessed CTA-based artificial intelligence for detecting anterior-circulation occlusions, using 31 reports involving 15 708 patients.
The Impact of Outcome Measures for Responder Analyses in Placebo-Controlled Trials of Pharmacological Treatments for Neuropathic Pain.
This meta-analysis examined how dichotomous responder definitions affect estimated treatment effects in placebo-controlled pharmacological trials for neuropathic pain.
Systematic Review of Smart Home Assistive Technology Devices for Supporting People With Dementia Living in Their Homes.
This systematic review and meta-analysis assessed smart home and wearable assistive technologies for people with dementia living at home or in supported accommodation.
Serum Insulin-Like Growth Factor-1 (IGF-1) in Parkinson's Disease: A Systematic Review and Meta-Analysis.
This systematic review and random-effects meta-analysis examined observational studies comparing serum IGF-1 in people with Parkinson’s disease (PD) and healthy controls, and studies of associations with PD symptoms.
October 202617
Pharmacological Interventions for Neurological Manifestations of Ataxia-Telangiectasia: An Updated Systematic Review and Meta-analysis of Randomized Controlled Trials.
This updated systematic review and meta-analysis examined randomized trials of pharmacological treatments for neurological manifestations of ataxia-telangiectasia in children and adults.
COQ8A-Associated Ataxia in a Colombian Patient Presenting with Bilateral Ptosis and Response to CoQ10 Supplementation.
A 67-year-old woman with consanguineous parents had gait instability and exercise intolerance from age 10, progressing very slowly.
Unveiling Asymptomatic Atrioventricular Reciprocating Tachycardia in a Patient With Wolff-Parkinson-White Syndrome and Multiple Sclerosis.
A 54-year-old woman with secondary-progressive multiple sclerosis was admitted with a complicated urinary tract infection. Her initial ECG showed sinus tachycardia without preexcitation, but telemetry captured a…
The Effects of Virtual Reality Group Reminiscence Therapy on Agitation, Cognition, Depression and Social Function in Patients With Alzheimer's Disease.
This assessor-blinded randomised controlled trial evaluated multisensory virtual reality group reminiscence therapy in 60 people with Alzheimer’s disease, comparing twice-weekly 40-minute sessions for 8 weeks with…
The Effect of Bupropion in Peripheral Neuropathic Pain A Randomized, Double-Blind, Placebo-Controlled Study.
This randomized, double-blind, placebo-controlled crossover study assessed bupropion for peripheral neuropathic pain and whether response varied with conditioned pain modulation (CPM) or sensory phenotype.
Between Skin and Brain: A Systematic Review of 712 Cases 1976-2025 Reveals a Highly Diverse Disease Spectrum in Chaetothyriales.
This systematic review examined the global epidemiology, causative species, clinical presentations, and outcomes of 712 reported Chaetothyriales infections from 1976 to 2025.
First-in-Human Phase 1b/2a Trial Shows Safety with MEK 1/2 Inhibitor EDV2209 as A Novel Treatment for Spontaneous Subarachnoid Hemorrhage.
The STOP-DCI first-in-human Phase 1b/2a interventional, randomized, double-blind, placebo-controlled trial evaluated intracerebroventricular EDV2209, a MEK 1/2 inhibitor, in patients with severe spontaneous subarachnoid…
Maternal and Fetal Safety Outcomes of Thrombolytics for Ischemic Stroke in Pregnancy: A Systematic Review and Aggregated Case Series.
This systematic review and Bayesian aggregated case series examined maternal and fetal outcomes after thrombolytic treatment during pregnancy.
Clinical Reasoning: A 60-Year-Old Woman With Progressive Dysarthric Speech and Gait Instability.
A 60-year-old woman developed progressive dysarthria and gait instability over 2 months, with chronic constipation and substantial weight loss.
The effect of acupuncture-rehabilitation therapy on brain functional plasticity in motor aphasia after ischemic stroke: a randomized clinical neuroimaging trial.
This randomized clinical neuroimaging trial assigned 26 patients with motor aphasia after ischemic stroke to conventional rehabilitation (CR) or CR plus acupuncture-rehabilitation (A-R); 26 healthy controls provided…
Auricular point acupressure for chemotherapy-induced peripheral neuropathy: a randomized controlled trial.
This pragmatic randomized controlled trial evaluated auricular point acupressure (APA) for chemotherapy-induced peripheral neuropathy in 227 cancer survivors, comparing in-person delivery, video-guided self-placement…
Bupropion-Induced Aseptic Meningitis: Postmarketing Safety Evaluation and Case Report.
During routine safety surveillance, the FDA identified two cases of aseptic meningitis associated with bupropion. One was sufficiently well documented for the authors to assess the causal association as probable.
Anti-N-Methyl-D-Aspartate Receptor Encephalitis Presenting as Acute Psychosis in a Renal Transplant Recipient Under Chronic Immunosuppression.
A 38-year-old renal transplant recipient taking tacrolimus and mycophenolate presented with abrupt psychosis, including delusions, auditory hallucinations, and severe agitation.
A Systematic Review and Meta-Analysis of Randomized Clinical Trials Comparing the Effectiveness of Corticosteroid Injection Versus Night Splints in Patients With Carpal Tunnel Syndrome.
This systematic review and meta-analysis of randomized controlled trials compared corticosteroid injection (CSI) with night splinting (NS) for carpal tunnel syndrome.
Hypothalamic Neurochemical and Microglial Suppression in Long-Standing Human Hibernation-Like Syndrome.
A 57-year-old woman had a more than 30-year history of winter-associated hypothermia, neuroendocrine instability, psychomotor suppression and circannual rhythmicity.
The Effects of Mind-Body Exercise on Cognitive Function and Peripheral Blood BDNF in Elderly People With Mild Cognitive Impairment: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis pooled 17 randomized controlled trials involving 1,251 older adults with mild cognitive impairment to assess mind-body exercise and cognition and peripheral blood BDNF.
Establishing Potosi Virus as a Human Pathogen: Fatal Neuroinvasive Disease in a B-Cell-Depleted Patient.
A 37-year-old woman with multiple sclerosis receiving long-term rituximab developed rapidly progressive dementia. MRI showed progressive generalized atrophy, while cerebrospinal fluid had only transient, minimal…
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