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845 articles

March 202617

Case ReportPathology (Anatomic & Clinical)

Lung Cancer Initially Presenting with Diffuse Alveolar Damage and Brain Infarction: An Autopsy Case Report.

A 67-year-old man presented with dyspnea, right hemiparesis, and dysarthria. Chest CT showed extensive pulmonary infiltrates and a small left upper-lobe nodule; brain MRI demonstrated multiple acute cerebral infarctions.

Intern MedMar 17, 2026Read case
Case ReportInfectious Diseases

Pulmonary Cryptococcosis Mimicking Lung Metastasis in a Patient with Pancreatic Cancer: A Case Report and Review of the Literature.

A man with pancreatic head cancer, liver metastases, and a germline BRCA2 mutation received FOLFOX chemotherapy. Although the primary tumor responded and CA19-9 levels declined, imaging showed a rapidly enlarging…

Intern MedMar 17, 2026Read case
Case ReportOncology (Medical)

Combined Hepatocellular-cholangiocarcinoma Patient Treated with Durvalumab Plus Gemcitabine and Cisplatin.

A 55-year-old man with lower abdominal pain and diarrhea was referred to our hospital. Computed tomography (CT) revealed a hypovascular liver tumor, lymph node/bone metastases, and peritoneal dissemination.

Intern MedMar 17, 2026Read case
Case ReportInfectious Diseases

A Rare Case of Slowly Progressive Meningitis Caused by Streptococcus intermedius.

An elderly patient with cancer developed meningitis due to Streptococcus intermedius, with an unusually gradual, subacute-to-chronic course. Blood cultures confirmed S.

Intern MedMar 17, 2026Read case
Case ReportPulmonology

Late-onset Acute Cellular Rejection after Lung Transplantation Triggered by a Fluctuation in the Tacrolimus Trough Level Which Was Successfully Treated with Steroid Pulse Therapy.

A lung transplant recipient developed dyspnea, diffuse ground-glass opacities, and reduced lung function 18 months after transplantation. Biopsy findings supported acute cellular rejection (ACR).

Intern MedMar 17, 2026Read case
Case ReportRheumatology

VEXAS Syndrome with an Improvement of Chest Shadows without Immunosuppressive Therapy.

An 86-year-old man presented with elevated C-reactive protein, bicytopenia, and bilateral chest shadows. Bronchoalveolar lavage showed an increased lymphocyte count.

Intern MedMar 17, 2026Read case
Case ReportOncology (Medical)

Peliosis Hepatis Induced by Tamoxifen Therapy in a Patient with Breast Cancer.

A woman in her 50s receiving multimodal treatment for breast cancer, including tamoxifen, was found on imaging to have a 3-cm hepatic lesion one year after surgery. Tumor marker levels were mostly normal.

Intern MedMar 17, 2026Read case
Case ReportOncology (Medical)

Enhancer of Zeste Homolog 1 and 2 Inhibitor-induced Colitis Mimicking Immune Checkpoint Inhibitor-induced Colitis.

An 80-year-old woman with relapsed nodal T-follicular helper cell lymphoma developed severe watery diarrhea while receiving valemetostat, an EZH1/2 inhibitor. Colonoscopy showed diffuse mucosal erythema and edema.

Intern MedMar 17, 2026Read case
Case ReportPulmonology

Methotrexate-induced Other Iatrogenic Immunodeficiency-associated Lymphoproliferative Disorder with Diffuse Ground-glass Opacities Diagnosed Using a Cryobiopsy.

A 77-year-old woman with rheumatoid arthritis and advanced gastric cancer developed diffuse ground-glass opacities on chest CT and markedly elevated serum lactate dehydrogenase. Intravascular lymphoma was considered.

Intern MedMar 17, 2026Read case
Case ReportNeurology

Diabetic Striatopathy Following Radiological Improvement: An Autopsy-confirmed Case Report and Literature Review.

A patient with poorly controlled diabetes developed hemichorea in the setting of diabetic striatopathy and right cerebellar hemorrhagic infarction. The hemichorea emerged despite radiological improvement.

Intern MedMar 17, 2026Read case
Case ReportDermatology

A rare case of migrating dermal filler mimicking lymphadenopathy.

A 30-year-old man presented with bilateral submandibular nodules. MRI showed bilateral masses, while sonography suggested cysts or lymph nodes.

J Am Dent AssocMar 17, 2026Read case
Case ReportPathology (Anatomic & Clinical)

Paraprotein interference in bilirubin assays: A case of multiple myeloma highlighting the reliability of dry chemistry.

A 60-year-old man with nonspecific symptoms had no jaundice and normal-appearing imaging. Wet chemistry testing reported total bilirubin of 0.39 mg/dL and an impossible direct bilirubin of -7.67 mg/dL.

Ann Clin BiochemMar 16, 2026Read case
Case ReportEndocrinology

Falsely elevated urinary C-peptide during angiotensin receptor-neprilysin inhibitor therapy: A case report.

A 54-year-old man with type 2 diabetes and hypertension was admitted for preoperative glycemic control after being diagnosed with aortic valve insufficiency.

Ann Clin BiochemMar 16, 2026Read case
Case ReportOncology (Medical)

PTEN and PIK3CA Mutation Positive Breast Neuroendocrine Carcinoma Treated with Molecularly Targeted Therapy Including Capivasertib.

A woman in her 40s with metachronous bilateral breast cancer was diagnosed with breast neuroendocrine carcinoma after rapid progression and metastases to bone, liver, and lung were detected during semiannual follow-up.

Tohoku J Exp MedMar 12, 2026Read case
Case ReportRheumatology

Pulmonary Involvement in ANCA-associated Vasculitis Overlapping with Long-standing Systemic Lupus Erythematosus.

A 74-year-old woman with long-standing systemic lupus erythematosus (SLE) presented with fever and bilateral centrilobular pulmonary nodules with bronchial wall thickening on computed tomography.

Intern MedMar 10, 2026Read case
Case ReportObstetrics & GynecologyOpen access

Progressive MRI changes in lobular endocervical glandular hyperplasia suggesting malignant transformation: report of two cases with histopathologic correlation.

Two premenopausal women with previously diagnosed lobular endocervical glandular hyperplasia (LEGH) underwent serial MRI follow-up and were subsequently found to have minimal deviation adenocarcinoma (MDA) associated…

Abdom Radiol (NY)Mar 9, 2026Read case
Case ReportEndocrinology

Atypical Subacute Thyroiditis without Thyroid Dysfunction: A Report of Two Cases.

Two patients presented with anterior neck pain and tender thyroid nodules, with elevated inflammatory markers and ultrasound findings characteristic of subacute thyroiditis (SAT).

Intern MedMar 3, 2026Read case

February 20267

Case ReportCardiology

A Rapid Pathological Diagnosis Based on Unfixed Frozen Tissue Section Leads to the Misdiagnosis of Eosinophilic Myocarditis as Lymphocytic Myocarditis.

A 64-year-old man presented with fever and progressive dyspnea, with clinical and imaging findings suggesting acute myocarditis.

Intern MedFeb 24, 2026Read case
Case ReportOphthalmology

Ophthalmic Rosai-Dorfman Disease and the Revised Classification of Histiocytoses: A Case Series and Review of the Literature.

At one academic institution, a 10-year review identified 48 patients with Rosai-Dorfman disease (RDD); 12 had ophthalmic findings. Their presentations included cutaneous, nodal, and extranodal forms.

Ophthalmic Plast Reconstr SurgFeb 24, 2026Read case
Case ReportPsychiatry

Metabolism, Not Mendacity: Rethinking Prolonged Cocaine Positivity.

A 42-year-old man with severe stimulant use disorder had urine tests positive for cocaine metabolites for 18 days, including 12 days after abstinence was verified in a residential program.

J Addict MedFeb 23, 2026Read case
Case ReportPathology (Anatomic & Clinical)Open access

A Rare Case of Homicidal Asphyxia Involving Combined Mechanisms By Multiple Assailants.

A 20-year-old man was found inside a locked suitcase after a homicide. Examination showed facial cyanosis, subconjunctival and scleral hemorrhages, and patterned neck abrasions.

Am J Forensic Med PatholFeb 19, 2026Read case
Case ReportPathology (Anatomic & Clinical)

Myxoid Solitary Fibrous Tumor of the Vulva: A Diagnostic Pitfall.

A 35-year-old woman presented with a slowly enlarging vulvar mass that imaging suggested was a benign cystic lesion. Histology instead showed a predominantly myxoid spindle-cell tumor, with staghorn-shaped vessels at…

Int J Gynecol PatholFeb 18, 2026Read case
Case ReportInfectious Diseases

Fatal Fungal Peritonitis Caused by Aspergillus udagawae: An Autopsy Case Report.

A 56-year-old man with chronic progressive pulmonary aspergillosis caused by multidrug-resistant Aspergillus udagawae developed acute abdominal pain.

Intern MedFeb 10, 2026Read case
Case ReportGastroenterology

Endoscopic Submucosal Dissection as a Diagnostic and Minimally Invasive Therapeutic Excision Modality for Primary Anorectal Malignant Melanoma.

An 82-year-old man with primary anorectal malignant melanoma underwent endoscopic submucosal dissection (ESD), which served as a total biopsy and minimally invasive excision.

Intern MedFeb 10, 2026Read case

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