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1320 articles
November 202624
Spinocerebellar Ataxia Type 6 Concurrent with Normal-Pressure Hydrocephalus: A Case Report.
A 73-year-old man with two years of progressive gait disturbance had gaze-evoked nystagmus, dysarthria, limb ataxia, a broad-based shuffling gait, and urinary urgency.
Late-onset Niemann-Pick C disease in a patient with spastic ataxia and hyperkinetic involuntary movements: a case report.
A woman with late-onset Niemann-Pick disease type C1 presented from age 50 with progressive postural instability, falls, spastic ataxia, and prominent upper-limb hyperkinetic movements.
Immune checkpoints inhibitors in the treatment of progressive multifocal leukoencephalopathy: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed immune checkpoint inhibitors (ICIs) for progressive multifocal leukoencephalopathy (PML), pooling reports involving 186 patients from 52 articles.
A rare neurological adverse event of palbociclib: a chronic inflammatory demyelinating polyneuropathy (CIDP) mimic.
A 43-year-old woman with metastatic HR-positive/HER2-negative breast cancer developed progressive, asymmetric weakness and sensory symptoms about two weeks after starting palbociclib.
Efficacy and safety of cenobamate in the treatment of drug-resistant epilepsy: a systematic review and meta-analysis in adult, pediatric, and combined populations.
This systematic review and random-effects meta-analysis assessed cenobamate efficacy and safety for drug-resistant epilepsy in adults, children, and mixed-age populations.
Effects of Probiotics on Migraine in Children and Adults: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed probiotics for migraine prevention in placebo-controlled trials involving adults and children.
Risk factors for cognitive impairment in patients undergoing hemodialysis: an umbrella review and meta-analysis.
This umbrella review and meta-analysis examined factors associated with cognitive impairment and cognitive frailty in adults receiving maintenance hemodialysis. It included five meta-analyses covering 97 associations.
Immunothrombosis Biomarkers and Multi-Omics Profiles After Successful Recanalization in Patients Receiving Ischemic Postconditioning: An Exploratory Analysis of the INSPIRE Trial.
This exploratory secondary analysis of the randomized INSPIRE trial examined 60 patients with ischemic stroke after successful endovascular thrombectomy recanalization.
Radiomics performance to identify high-risk carotid artery plaques: a systematic review.
This systematic review assessed radiomics-based models for identifying high-risk carotid plaques. It included 28 studies involving 6,108 patients, 72.4% of whom were male.
Homozygous SCA8 presenting as severe axonal neuropathy without overt cerebellar involvement.
A 35-year-old man with progressive limb weakness beginning at age 15 had severe proximal muscle atrophy and absent deep tendon reflexes, without overt cerebellar signs.
Singing-based interventions for motor and non-motor symptoms in Parkinson's disease: a systematic review.
This systematic review examined interventional studies of singing-based rehabilitation for motor and non-motor symptoms in people with Parkinson’s disease.
KARS1-Related Infantile-Onset Progressive Leukoencephalopathy With or Without Deafness: A Novel Variant and Phenotypic Expansion.
A two-year-old Iranian boy born to non-consanguineous parents presented with developmental delay, seizures, and sensorineural hearing loss.
Clinical, neuroimaging and electroencephalographic differences between pediatric and adult HaNDL: a systematic review and pooled individual patient analysis.
This PRISMA 2020-guided systematic review and pooled individual patient analysis compared clinical and ancillary findings in pediatric and adult patients with HaNDL, a self-limited headache syndrome with cerebrospinal…
Tenecteplase Before Thrombectomy at 4.5 to 24 Hours for Basilar Artery Occlusion: The ATTENTION LATE Randomized Clinical Trial.
This multicenter, open-label, blinded-endpoint randomized clinical trial compared intravenous tenecteplase before endovascular thrombectomy (EVT) with EVT alone in patients with moderate to severe basilar artery…
Pediatric suprasellar primary CNS lymphoma with cavernous sinus invasion and ischemic stroke: a case report and systematic review.
A 12-year-old immunocompetent girl presented with high fever, severe headache, and diplopia, followed by rapid neurological deterioration.
Tegmental Heterotopia in PHACE Syndrome: A Previously Undescribed Feature.
The report describes two infants with PHACE syndrome and infratentorial neuroglial heterotopia involving the tectal plate. A 6-week-old infant with a right segmental facial hemangioma and ventricular septal defect had…
Imaging and Clinical Features of Secondary Spinal Cord Lymphoma: A 2-Center Case Series.
This two-center case series describes 18 cases of secondary spinal cord lymphoma. The authors examined spinal MRI findings and their relationship to intracranial disease, systemic lymphoma, and clinical features.
Imaging Modalities to Visualize Deep Cerebral Perforating Arteries: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed imaging methods for visualizing deep cerebral perforating arteries in human studies.
Network-Based Deep Brain Stimulation Rescue After Magnetic Resonance-Guided Focused Ultrasound Thalamotomy for Essential Tremor: Two Targeting Strategies.
Two men developed recurrent essential tremor after MRgFUS thalamotomy. In the 71-year-old, DBS was placed along a Vim–posterior subthalamic area trajectory.
Clinical Reasoning: An 18-Year-Old Woman With Episodic Stiffness, Exercise Intolerance, and Weakness: Decoding a Neuromuscular Mystery.
An 18-year-old woman had longstanding episodic muscle stiffness, cold sensitivity, exercise intolerance, and stable proximal weakness.
Pearls & Oy-sters: The Price of Patency: Intractable Headache Subsequent to Fourth Ventricular Recanalization.
A 61-year-old woman with secondary fourth ventricular hemorrhage was treated using an IRRAflow active irrigation and drainage system.
Germline Genetic Variants and Epilepsy Surgery Response: Individual Participant Pooled Analysis of 272 Patients.
This systematic review and individual-participant pooled analysis examined seizure outcomes after resection or laser ablation in 272 people with pathogenic or likely pathogenic germline epilepsy variants, excluding…
Prognostic value of the systemic inflammation response index (SIRI) in glioma: A meta-analysis.
This meta-analysis assessed whether the systemic inflammation response index (SIRI) predicts outcomes in patients with glioma. It pooled evidence from eight retrospective cohort studies involving 1,778 patients.
An Approach to Acute Cranial Symptoms in Primary Care: Lesson From a Case of Miller Fisher Syndrome.
A 38-year-old woman developed acute diplopia, right eye pain, headache, and perioral numbness two weeks after an upper respiratory infection.
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