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1320 articles
September 202624
Semiology of Opercular Epilepsies.
This systematic review analyzed the semiology of 'pure' opercular seizures in 70 patients across four anatomical groups: frontal, central, parietal, and temporal operculum.
Dual Transcranial Direct Current Stimulation Modulates Hierarchical Functional Network Organization in Post-Stroke Cognitive Impairment: A Randomized Controlled Trial.
This randomized controlled trial evaluated the efficacy of dual transcranial direct current stimulation (tDCS) in 74 patients with post-stroke cognitive impairment (PSCI).
A standardized framework resolves ambiguity in motor neuron loss across neurodegenerative diseases.
This systematic review and meta-analysis examined motor neuron loss in spinal muscular atrophy (SMA) mouse studies, highlighting a 60% variability in reported loss due to spinal cord sampling methods.
Paraneoplastic Myopathy as a Possible Initial Presentation of Sporadic Burkitt Lymphoma in an Immunocompetent Adult: A Case Report.
An immunocompetent adult male presented with acute progressive proximal muscle weakness and elevated creatine phosphokinase levels. Extensive evaluations ruled out autoimmune and metabolic causes.
Pulmonary arteriovenous malformation (PAVM) with hereditary haemorrhagic telangiectasia (HHT): a rare cause of paradoxical embolic stroke.
A woman in her 40s presented with right-sided hemiparesis, and MRI revealed a left thalamic infarction. Further investigation identified pulmonary arteriovenous malformation (PAVM) associated with hereditary…
Meningioma regression following discontinuation of depot medroxyprogesterone acetate.
Three patients with meningioma who were under active surveillance experienced tumor regression after discontinuing depot medroxyprogesterone acetate (dMPA).
Smoking and disability outcomes in multiple sclerosis: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the impact of smoking on disability outcomes in multiple sclerosis (MS) across 18 studies.
Whole-exome sequencing reveals a novel frameshift and a recurrent nonsense SPG11 variant causing rare familial amyotrophic lateral sclerosis type 5 in two consanguineous Pakistani families.
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects both upper and lower motor neurons, disturbing communication between the brain and muscles.
Acute ischemic stroke revealing cryptococcal meningitis in an HIV-infected patient with a relatively preserved CD4 count: a case report.
A 28-year-old man with a long history of HIV presented with acute right-sided hemiparesis. Despite a CD4 count of 302 cells/mm³, brain imaging revealed an acute infarction in the left internal capsule and hydrocephalus.
The Prevalence of Neuropathic Pain in Multiple Sclerosis-A Systematic Review and Meta-Analysis Using the NeuPSIG Algorithm.
This systematic review and meta-analysis estimated the prevalence of neuropathic pain in multiple sclerosis (MS) using the NeuPSIG algorithm.
CSF Tau and Amyloid Biomarkers in Cognitive Impairment Across the ALS-FTD Spectrum: A Systematic Narrative Review and Evidence Map.
This systematic narrative review examined the associations between cerebrospinal fluid (CSF) tau and amyloid biomarkers and cognitive impairment in 638 participants across the ALS-FTD spectrum.
The WNT/β-catenin Pathway and Matrix Metalloproteinase-9 in hypermobile Ehlers-Danlos Syndrome and Autism Spectrum Disorder: A Possible Connection.
This narrative review explores the connection between hypermobile Ehlers-Danlos Syndrome (hEDS) and Autism Spectrum Disorder (ASD), highlighting their symptom overlap and comorbidity.
Increased Libido Following Brivaracetam Initiation: A Case Report of Temporal Lobe Epilepsy.
A woman in her 70s with drug-resistant temporal lobe epilepsy and mild cognitive impairment experienced increased libido and self-stimulatory behavior after starting brivaracetam for her seizures.
Could Subjective Cognitive Complaints Give the Facts of Objective Cognitive Impairments in Non-Central Nervous System Cancer? A Systematic Review.
This systematic review examined the relationship between subjective cognitive complaints (SCCs) and objective neuropsychological assessments in non-central nervous system cancer patients.
The Neuroscience of Religious and Spiritual Practices: A Systematic Review of Neurotheological Evidence.
This systematic review examined the neurobiological effects of religious and spiritual practices across various traditions, synthesizing findings from 105 studies using neuroimaging techniques.
Biallelic VPS41 Variants in Autosomal Recessive Spinocerebellar Ataxia 29 Resolved by Long-Read Sequencing and RNA Analysis.
Biallelic variants in VPS41, encoding a subunit of the HOPS complex, cause autosomal recessive spinocerebellar ataxia 29 (SCAR29), a rare neurodevelopmental disorder with an incompletely defined phenotypic and molecular…
The Role of Hippocampal Interneuron Migration in Neurodevelopmental Disorders: A Systematic Review.
This systematic review examined the role of aberrant hippocampal interneuron migration in neurodevelopmental disorders, analyzing 29 studies.
Neuropathy With Demyelinating Features in a Patient With Biallelic HARS1 Variants.
A 25-year-old male presented with Charcot-Marie-Tooth disease type 1 and mild intellectual disability. Genetic analysis revealed he was compound heterozygous for two pathogenic HARS1 variants: a maternally inherited…
Intensive blood pressure lowering after spontaneous intracerebral haemorrhage for secondary stroke prevention (RECAP-ICH): a systematic review and individual participant data meta-analysis.
This systematic review and individual participant data meta-analysis evaluated the effects of intensive blood pressure-lowering treatment on recurrent stroke in 2944 adults with a history of spontaneous intracerebral…
Nonsystemic Vasculitic Neuropathy Presenting as Inflammatory Demyelinating Polyradiculoneuropathy.
A 57-year-old man presented with acute ascending weakness, sensory loss, and facial weakness following a febrile illness. Initial improvement was followed by neurological decline despite treatment.
Possible Contribution of Multiple Sclerosis Pathology to Treatment-Resistant Schizophrenia: A Case Study.
A woman in her 50s presented with persecutory delusions and a sense of being surveilled, initially diagnosed with schizophrenia. Despite long-term antipsychotic treatment, her symptoms worsened.
Anakinra in Severe RSV-Associated Autoinflammatory Encephalopathy With Delayed ADEM-Like Changes.
Two previously healthy children developed rapidly progressive encephalopathy following RSV infection. Initial brain MRI scans were normal, but subsequent imaging revealed multifocal white matter lesions resembling acute…
Biallelic SCO2 Variants Presenting as Motor-Predominant Axonal Neuropathy With Complex IV Deficiency.
SCO2 encodes a mitochondrial copper chaperone required for cytochrome c oxidase (COX) assembly and is classically associated with severe multisystem mitochondrial disease.
Mechanical Thrombectomy in Ischemic Stroke With a Medium or Distal Arterial Occlusion: The DISCOUNT Randomized Clinical Trial.
The DISCOUNT randomized clinical trial evaluated the efficacy of thrombectomy plus medical treatment versus medical treatment alone in patients with acute ischemic stroke due to medium or distal vessel occlusions.
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