Increased Libido Following Brivaracetam Initiation: A Case Report of Temporal Lobe Epilepsy.

Neuropsychopharmacol RepSep 1, 2026
Case ReportNeurologyPsychiatryOpen access

Toru Horinouchi, Taiki Matsuyama, Mayusa Mito et al.

✦ AI-curated · Sources linked

Case in brief

A woman in her 70s with drug-resistant temporal lobe epilepsy and mild cognitive impairment experienced increased libido and self-stimulatory behavior after starting brivaracetam for her seizures. These symptoms emerged three weeks post-initiation and were disclosed during a follow-up visit. Upon discontinuation of brivaracetam, her symptoms improved significantly within two weeks, with no changes in seizure frequency or cognitive function noted.

Diagnostic / clinical pearl

Clinicians should monitor for changes in libido in patients starting brivaracetam, as increased sexual urges may occur despite the drug's reputation for minimal psychiatric side effects.

Source

PubMed · PMID 42675017Free full text on PubMed Central

Published in Neuropsychopharmacol Rep. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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