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845 articles
August 202617
Diffuse Long-segment Colonic Wall Thickening Mimicking Abdominal Tuberculosis: A Diagnostic Challenge Revealing Signet Ring Cell Carcinoma in a 24-year-old Male.
A 24-year-old man with long-standing abdominal pain had contrast-enhanced CT showing target-like diffuse bowel-wall thickening from the terminal ileum through the entire transverse colon, with ascites and omental…
Sitagliptin-associated Bullous Pemphigoid Complicated by Secondary Candidiasis, Urosepsis, and Gastrointestinal Bleeding in an Elderly Diabetic Woman.
A 74-year-old woman with type 2 diabetes and hypertension developed painful widespread blisters and oral erosions after approximately 2 years of sitagliptin 100 mg once daily.
Honey bee sting deaths at medicolegal autopsy: A case series demonstrating variable manifestations of anaphylactic fatality.
Three people in Lucknow, India, died after rapid collapse following honey bee attacks. At medicolegal autopsy, sting burdens ranged from limited exposure to an estimated 200 stings.
Oral Rhabdomyomatous Hamartoma in a Paediatric Patient: Case Report a Rare Lesion.
An 8-year-old boy presented with a submucosal nodule on the left lateral border of the tongue. A dermoid cyst was initially suspected, but histopathological examination showed thick, interlacing bundles of skeletal…
Multifocal primary hepatic epithelioid hemangioendothelioma: a case in which tumor biopsy was critical to prevent misdiagnosis.
An 82-year-old woman undergoing postoperative surveillance for bladder cancer was found to have multiple hepatic masses on contrast-enhanced CT.
Clinical Profile, Electrophysiology, and Short-Term Outcomes of Pediatric-Onset Autoimmune Nodopathy-A Case Series.
The report describes three children with autoimmune nodopathy associated with antibodies to neurofascin 140, alone or with neurofascin 186.
Diagnostic accuracy of nuclear STAT6 immunohistochemistry for solitary fibrous tumour: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the diagnostic accuracy of nuclear STAT6 immunohistochemistry for solitary fibrous tumours (SFT) across 23 studies involving 1216 SFT and 4715 comparators.
Cell Blocks and the Milan System for Reporting Salivary Gland Cytopathology: A Meta-Analysis.
This meta-analysis evaluated the distribution of Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) categories and their associated risks of malignancy (ROM) in salivary gland fine-needle aspirations…
Medico-legal aspects of fatal ricin poisoning: a systematic review of clinical manifestations, toxicological findings and autopsy results.
This PRISMA-guided systematic review synthesized original studies, case reports, and case series describing fatal or near-fatal human ricin exposure.
Assessing Graded Histological Regression as Basis for Treatment Modification after Neoadjuvant Therapy in LAGC: An Exploratory Phase II Study.
This prospective, single-centre, open-label, randomised phase II trial assessed whether graded histologic regression (GHR) below 50% could guide adjuvant chemotherapy modification in locally advanced gastric cancer…
Endoscopic Ultrasound-Guided Fine Needle Aspiration Diagnosis of Pancreatic Intraductal Tubulopapillary Neoplasm: A Cytology Case Report.
An 82-year-old woman had a pancreatic head mass and miliary pulmonary nodules that raised radiologic concern for pancreatic adenocarcinoma.
Aural Squamous Papilloma in a 5-year-old: A Rare Case Report with Literature Review.
A 5-year-old boy had chronic itching, aural fullness, and a progressively enlarging warty lesion in the left external auditory canal.
Obstructed by Metastasis: Dual Biliary and Gastric Outlet Obstruction from Metastatic Breast Carcinoma.
A 57-year-old woman with a history of HER2-positive, hormone-receptor-negative breast carcinoma treated four years earlier presented with jaundice, vomiting, early satiety, and weight loss.
A Wolf in Sheep's Clothing: Laryngeal Myxoma Masquerading as a Vocal Cord Polyp.
A 19-year-old woman presented with one month of hoarseness. Laryngoscopy showed a small polypoid vocal-cord lesion, which was surgically removed.
Xanthogranulomatous epithelial tumour of the calcaneus in a 32-year-old female: a rare entity.
A 32-year-old woman presented with 10 months of heel pain. Imaging showed a lytic lesion in the calcaneus, with giant cell tumour of bone and solid aneurysmal bone cyst among the initial considerations.
Primary Cutaneous Anaplastic Large Cell Lymphoma in a Patient With Li Fraumeni Syndrome.
A 64-year-old man with Li-Fraumeni syndrome and a germline TP53 p.R196* mutation presented with a solitary ulcerated nodule on the left anterior thigh.
Molecular autopsy in unexplained sudden death: a systematic review and meta-analysis of ACMG-corrected diagnostic yield, genomic architecture, and family translation.
This PRISMA-based systematic review and random-effects meta-analysis assessed postmortem genetic testing in unexplained sudden death.
July 20267
Low-Grade and Intermediate-Grade Apocrine Intraductal Carcinoma Arising in a Nevus Sebaceous of Jadassohn.
A 93-year-old woman had low- and intermediate-grade apocrine intraductal carcinoma arising in a nevus sebaceous of Jadassohn.
Otopathology of Pediatric Acute Tuberculous Meningitis-Case Series.
This case series presents three temporal bones from infants who succumbed to acute tuberculous meningitis (TBM). Pathological examination revealed significant inner ear damage, including cochlear fibrosis, atrophy of…
Cross-Compartment Proteomic Signatures in Human Diabetic Retinopathy: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis synthesized proteomic findings from 28 human diabetic retinopathy studies spanning vitreous, aqueous, plasma or serum, tears, and urine.
Tofogliflozin alters amino acid metabolism in gut microbiota linked to hepatic transcriptomic signatures in MASLD.
This prespecified sub-analysis of a randomized controlled trial examined gut microbiota–liver associations in participants with MASLD and type 2 diabetes treated with tofogliflozin or glimepiride.
Endobronchial Ultrasound-guided Diagnosis of Occult Lung Adenocarcinoma with Normal Chest Radiograph.
A 59-year-old woman with cough, hemoptysis, and dyspnea had an unremarkable chest radiograph despite persistent symptoms. HRCT showed abrupt cutoff of the left lower lobe bronchus with distal collapse, suggesting an…
Extrapulmonary Tuberculosis with Seminal Vesicle Involvement in an Immunocompetent Patient.
A 54-year-old immunocompetent man presented with prolonged fever and a generalized seizure. Neuroimaging showed ring-enhancing lesions suggestive of tuberculomas; further evaluation found a seminal vesicle abscess and…
Dynamic Circulating Tumor DNA Methylation Monitoring Guiding Postoperative Surveillance in Nonmetastatic Colorectal Cancer: A Prospective, Randomized, Phase III FIND Trial.
The prospective, multicenter, randomized phase III FIND trial compared circulating tumor DNA (ctDNA) methylation-guided surveillance with standard CT monitoring after curative resection of nonmetastatic colorectal…
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