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1357 articles

November 202618

Clinical ResearchCardiologyOpen access

Specialist Referral for Cardiovascular Risk in Patients With Prostate Cancer: A Randomized Clinical Trial.

This multicenter randomized clinical trial tested whether routine cardiovascular-specialist referral improved risk-factor control and cardiovascular outcomes in patients with prostate cancer who were starting or had…

JAMA Intern MedNov 1, 2026Read summary
Clinical ResearchEndocrinology

Supraclavicular thermography does not isolate a brown adipose tissue signal during room temperature β-adrenergic stimulation in adults.

Two randomized, single-blind, placebo-controlled crossover trials studied thermogenic responses to β-adrenergic stimulation in healthy adults.

Physiol RepNov 1, 2026Read summary
Clinical ResearchPediatrics

Association of Caregiver Mental Health and a Childhood Parenting Intervention in China.

This clustered randomized controlled trial tested whether caregiver mental health modified the effects of a center-based parenting intervention in 100 rural Chinese villages.

PediatricsNov 1, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Optimal Exercise Dose for Improving Multidimensional Health Outcomes in Colorectal Cancer Patients: A Systematic Review, Meta-Analysis and Meta-Regression.

This systematic review, meta-analysis and meta-regression examined exercise dose-response relationships in colorectal cancer patients.

Eur J Sport SciNov 1, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Toxoplasma gondii in Ethiopia: A Systematic Review and Meta-Analysis of Infection Prevalence and Associated Risk Factors in Humans and Animals.

This systematic review and random-effects meta-analysis estimated Toxoplasma gondii prevalence and associated risk factors in humans and ruminants in Ethiopia, using studies published between 2012 and 2025.

Vet Med SciNov 1, 2026Read summary
Clinical ResearchObstetrics & Gynecology

The Effect of Game-based Mobile Application in Learning Postpartum Hemorrhage Management for Midwifery Students.

This two-phase randomized controlled study developed and evaluated a game-based mobile application for postpartum hemorrhage (PPH) management education.

Comput Inform NursNov 1, 2026Read summary
Clinical ResearchPathology (Anatomic & Clinical)

Cellular and Histopathological Hallmarks of Acute and Chronic Rejection in Vascular Composite Allografts: A Systematic Review.

This systematic review synthesized human studies describing cellular, immunophenotypic, and histopathological features of acute and chronic rejection in vascular composite allografts (VCAs).

Clin TransplantNov 1, 2026Read summary
Clinical ResearchPsychiatryOpen access

Structural Brain Correlates of Bulimia Nervosa Diagnosis and Symptom Severity: A Coordinated ENIGMA Eating Disorders Working Group Analysis.

This coordinated, international case-control meta-analysis examined structural MRI correlates of bulimia nervosa (BN) diagnosis and symptom severity across 17 cohorts at 13 sites.

JAMA PsychiatryNov 1, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Clinical outcomes of Day-7 blastocysts: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis compared frozen Day-7 blastocyst transfers with Day-5 and Day-6 transfers.

Hum Reprod UpdateNov 1, 2026Read summary
Clinical ResearchNeurologyOpen access

Inferior Frontal Gyrus Alterations in Freezing of Gait in Parkinson's Disease Without Evidence for Overall Hemispheric Lateralization: A Systematic Review and Activation Likelihood Estimation Meta-Analysis.

This systematic review and activation likelihood estimation meta-analysis examined neuroimaging differences between people with Parkinson’s disease who experience freezing of gait (freezers) and those who do not.

Eur J NeurosciNov 1, 2026Read summary
Clinical ResearchEmergency MedicineOpen access

Telehealth Treatment of Anxiety in Patients With Low-Risk Chest Pain in the Emergency Department: The PACER Randomized Clinical Trial.

The PACER multicentre, three-group randomised comparative effectiveness trial tested peer-supported internet-based cognitive behavioural therapy (iCBT) and therapist-delivered telehealth CBT against primary care…

JAMA Intern MedNov 1, 2026Read summary
Clinical ResearchEndocrinology

Prevalence of Diabetes in Low- and Middle-Income Countries' Incarcerated Populations: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis estimated diabetes prevalence among incarcerated people in low- and middle-income countries (LMICs), drawing on 23 studies with 107,473 participants.

Endocrinol Diabetes MetabNov 1, 2026Read summary
Clinical ResearchGeneral Surgery

Long-Term Marginal Bone Stability of BOPT Restorations on Bone-Level vs. Tissue-Level Implants: An 8-Year Prospective Clinical Study.

This prospective randomized clinical study compared eight-year marginal bone loss in 122 posterior bone-level and tissue-level implants restored using the Biologically Oriented Preparation Technique (BOPT) in 71…

Med Oral Patol Oral Cir BucalNov 1, 2026Read summary
Clinical ResearchPediatrics

Diagnosis and Management of Achalasia in Children, BSPGHAN and BAPS Consensus Statement.

This consensus statement addresses diagnosis and management of achalasia in children, for whom pediatric-specific guidelines were lacking.

Neurogastroenterol MotilNov 1, 2026Read summary
Clinical ResearchOncology (Medical)

Liposomal irinotecan and capecitabine plus bevacizumab as second-line therapy in metastatic colorectal cancer: A multicenter, single-arm study.

This multicenter, single-arm clinical study evaluated liposomal irinotecan, capecitabine, and bevacizumab as second-line therapy in patients with metastatic colorectal cancer progressing after oxaliplatin-based…

CancerNov 1, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Higher Fat Ration Formulations Minimize Energy Deficit During a Short Field Training Exercise.

This parallel, single-blinded randomized trial compared higher-fat, lower-volume Close Combat Assault Rations (CCAR) with First Strike Rations (FSR) in active-duty service members during a 5-day field training exercise.

Mil MedNov 1, 2026Read summary
Clinical ResearchEmergency Medicine

Performance of the i-Gel Versus King LT-D by Combat Medics Under Simulated Tactical Conditions: A Prospective Randomized Crossover Study.

This prospective randomized crossover study compared i-gel and King LT-D placement by active-duty combat medics after exertion while wearing full combat gear, using a high-fidelity manikin.

Mil MedNov 1, 2026Read summary
Clinical ResearchPulmonologyOpen access

PURE PRIME: implementing Pulmonary Rehabilitation in Primary care - a randomized-controlled feasibility trial.

PURE PRIME was a randomized controlled feasibility trial testing pulmonary rehabilitation (PR) in private physiotherapy or exercise physiology practices for people with chronic respiratory disease.

Ann Am Thorac SocNov 1, 2026Read summary

October 20266

Clinical ResearchOrthopedic SurgeryOpen access

Closed reduction in distal radius fractures: manual manipulation vs. finger trap traction-a prospective randomized controlled clinical trial.

This prospective, single-centre, 1:1 randomized controlled trial compared finger-trap traction (FTT) with additional manual reduction (MR) under haematoma block in 53 patients with acute distal radius fractures (AO…

Arch Orthop Trauma SurgOct 31, 2026Read summary
Clinical ResearchOncology (Medical)

Local ablative treatment for oligoprogression during immunotherapy in metastatic non-small-cell lung cancer: a systematic review and meta-analysis.

This PRISMA-compliant systematic review and meta-analysis assessed local ablative treatment (LAT), with continuation of the same immune checkpoint inhibitor, for oligoprogressive or oligo-resistant metastatic NSCLC…

OncoimmunologyOct 31, 2026Read summary
Clinical ResearchPsychiatry

Effect of electroconvulsive therapy on anhedonia in adults with major depressive disorder: A systematic review and meta-analysis.

This systematic review and meta-analysis examined changes in anhedonia among adults with major depressive disorder treated with electroconvulsive therapy (ECT).

J Affect DisordOct 31, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Evaluation of surgical outcomes and costs during the learning curve in robotic gynecologic surgery: a systematic review and meta-analysis.

This systematic review and meta-analysis examined whether surgical outcomes and costs differed between earlier and later cases of the same robotic gynecologic procedures.

J Robot SurgOct 31, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Glycemic control and weight loss benefits of fixed-ratio combinations of basal insulins and GLP1 receptor agonists in type 2 diabetes: A systematic review and network meta-analysis.

This systematic review and network meta-analysis compared fixed-ratio combinations of basal insulin and GLP-1 receptor agonists with basal insulin alone in adults with type 2 diabetes.

EndocrineOct 31, 2026Read summary
Clinical ResearchOphthalmologyOpen access

Toxoplasmosis-associated optic neuropathies: a systematic review and meta-analysis of clinical characteristics, diagnosis, and outcomes.

This systematic review and meta-analysis examined optic neuropathies associated with ocular toxoplasmosis (OT), combining observational studies and case reports.

Int OphthalmolOct 31, 2026Read summary

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