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1003 articles

September 202624

Clinical ResearchObstetrics & GynecologyOpen access

Hypertension in a Randomized Trial of Dolutegravir- Versus Efavirenz-Based Antiretroviral Therapy in Pregnant and Postpartum Women with HIV.

This randomized controlled trial evaluated incident hypertension in 626 pregnant and postpartum women with HIV receiving different antiretroviral therapies: dolutegravir (DTG) + emtricitabine/tenofovir alafenamide…

Clin Infect DisSep 2, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Predictors of Treatment Failure in Children With HIV Starting First-line Antiretroviral Therapy in the ODYSSEY Trial.

The ODYSSEY trial investigated predictors of treatment failure in 381 children starting first-line antiretroviral therapy (ART), primarily in Africa.

Clin Infect DisSep 2, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Safety, Pharmacokinetics, and Pharmacodynamics of Single-Dose Programmed Cell Death Protein 1 Inhibitor, Budigalimab, in People With HIV-1 With Antiretroviral Therapy-Suppressed Viral Load.

This Phase 1b randomized controlled trial evaluated the safety, pharmacokinetics, and pharmacodynamics of single-dose budigalimab, a PD-1 inhibitor, in 32 people with HIV-1 on antiretroviral therapy.

J Infect DisSep 2, 2026Read summary
Clinical ResearchInfectious Diseases

Recombinant vs Standard Influenza Vaccine in Adults With Severe Obesity: A Randomized Clinical Trial.

This randomized clinical trial evaluated the immune response to recombinant influenza vaccine (RIV) versus standard-dose vaccine (SD) in adults with severe obesity (BMI ≥35 kg/m²).

Clin Infect DisSep 2, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Comparison of Ceftolozane-Tazobactam and Ceftazidime-Avibactam in the Treatment of Multidrug-Resistant/Difficult-to-Treat Resistant Pseudomonas aeruginosa Infections: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis compared the efficacy of ceftolozane-tazobactam and ceftazidime-avibactam in treating multidrug-resistant Pseudomonas aeruginosa infections.

Clin Infect DisSep 2, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Safety and Tolerability of Oral Islatravir Once Monthly as Pre-exposure Prophylaxis in Cisgender Men and Transgender Women Who Have an Elevated Likelihood of HIV-1 Exposure: Results From the IMPOWER-24 Randomized Phase 3 Study.

The IMPOWER-24 randomized Phase 3 trial evaluated the safety and tolerability of monthly oral islatravir in cisgender men and transgender women at high risk for HIV-1 exposure.

Clin Infect DisSep 2, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Safety, Immunovirologic, and Central Nervous System Effects of PD-1 Inhibition in People With HIV Without Malignancy.

This phase 1 nonrandomized clinical trial evaluated the safety and effects of a single dose of pembrolizumab in 6 individuals with virally suppressed HIV.

J Infect DisSep 2, 2026Read summary
Clinical ResearchInfectious Diseases

Indirect Influenza Vaccine Effectiveness Under Randomized Conditions: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the indirect vaccine effectiveness (IVE) of influenza vaccines in non-institutional settings, analyzing data from 12 randomized controlled trials.

Clin Infect DisSep 2, 2026Read summary
Case ReportInfectious Diseases

Recurrent severe cutaneous reaction to fluoroquinolones and rifampicin in a human immunodeficiency virus-positive patient with disseminated tuberculosis: A rare case report.

A 47-year-old male with HIV and disseminated tuberculosis experienced recurrent maculopapular eruptions with mucosal involvement after exposure to multiple medications, including fluoroquinolones and rifampicin.

Indian J PharmacolSep 2, 2026Read case
Clinical ResearchInfectious Diseases

Determination of diagnostic cycle threshold cutoffs for qPCR-based prevalence surveys of soil-transmitted helminth infections.

This analysis of pre-intervention, population-based surveys within the DeWorm3 community-based cluster-randomized trial used high-throughput qPCR results from 29,980 samples to define cycle-threshold cutoffs for…

Microbiol SpectrSep 2, 2026Read summary
Clinical ResearchInfectious Diseases

A systematic review of digital healthcare-associated infection surveillance methods - comparisons and considerations for future program design.

This systematic review examined original hospital-based research on digital healthcare-associated infection (HAI) surveillance, identifying clinical and technical design elements and reported impacts.

J Hosp InfectSep 2, 2026Read summary
Clinical ResearchInfectious Diseases

Real-world implementation and impact of interventional antimicrobial stewardship programmes in Asian hospital settings: an updated systematic review mapped to IDSA/SHEA recommendations, the WHO Bacterial Priority Pathogens List, and AWaRe antibiotic categories.

This updated systematic review examined adult inpatient interventional antimicrobial stewardship studies in Southeast and East Asia, mapping programme components and outcomes to IDSA/SHEA recommendations, WHO AWaRe…

J Hosp InfectSep 2, 2026Read summary
Case ReportPediatrics

Neonatal Presentation of Suspected Vici Syndrome: A Case Report with Multisystem Features.

A newborn born to consanguineous parents, with a sibling who had died of an unspecified cause, presented with hypopigmentation, generalized hypotonia, recurrent severe infections, developmental delay, and cleft palate.

Ann Afr MedSep 2, 2026Read case
Clinical ResearchInfectious Diseases

A Meta-Analysis of Human Immunodeficiency Virus Drug Resistance in Pakistan.

This meta-analysis examined HIV drug resistance (HIVDR) in Pakistan, analyzing data from 51 studies involving over 1,500 participants from 2015 to 2025.

J Coll Physicians Surg PakSep 1, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Immunotherapeutic effect of MIP vaccine along with multidrug therapy (MDT) in leprosy: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the efficacy and safety of the MIP vaccine as an immunotherapeutic agent in conjunction with standard chemotherapy for multi-bacillary (MB) and pauci-bacillary (PB)…

Indian J Med ResSep 1, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Effect of a person-centered care intervention on return and sustained reengagement after treatment interruptions from HIV care in Zambia: A post-hoc analysis of a stepped-wedged cluster randomized trial.

This post-hoc analysis of a stepped-wedge cluster randomized trial evaluated a person-centered care (PCC) intervention in 24 Zambian clinics.

PLoS MedSep 1, 2026Read summary
Case ReportInfectious DiseasesOpen access

Acute ischemic stroke revealing cryptococcal meningitis in an HIV-infected patient with a relatively preserved CD4 count: a case report.

A 28-year-old man with a long history of HIV presented with acute right-sided hemiparesis. Despite a CD4 count of 302 cells/mm³, brain imaging revealed an acute infarction in the left internal capsule and hydrocephalus.

Neurol SciSep 1, 2026Read case
Clinical ResearchInfectious DiseasesOpen access

Dose Selection for Ceftibuten Combined with Avibactam Tomilopil, a Potential Oral Alternative to Carbapenems for Patients with Complicated Urinary Tract Infections.

This Phase I randomized controlled trial evaluated the safety, tolerability, and pharmacokinetics of avibactam tomilopil combined with ceftibuten in healthy participants.

J Clin PharmacolSep 1, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Implementation, adoption and impact of clinical decision support system for antibiotic prescribing in primary care: a systematic review.

This systematic review evaluated the implementation and impact of clinical decision support systems (CDSS) for antibiotic prescribing in primary care, analyzing 40 studies.

J Antimicrob ChemotherSep 1, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Factors that impact on healthcare workers' adherence with infection prevention and control (IPC) guidelines for COVID-19: a qualitative evidence synthesis.

This systematic review synthesizes qualitative evidence on factors affecting healthcare workers' adherence to infection prevention and control (IPC) guidelines for COVID-19.

Cochrane Database Syst RevSep 1, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Global Epidemiology of Diabetic Foot: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined the global epidemiology of diabetic foot (DF) disease in adults with diabetes mellitus, analyzing 89 studies.

Diabetes Metab Res RevSep 1, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Immunological effects of supervised exercise in long COVID in adults: A secondary analysis of a randomized crossover trial.

This secondary analysis of a randomized crossover trial evaluated the immunological effects of a 6-week supervised exercise program in adults with long COVID.

Physiol RepSep 1, 2026Read summary
Case ReportPediatrics

Pediatric Rickettsia massiliae Infection, Spain, 2023.

A pediatric patient in Spain presented with symptoms indicative of rickettsiosis, leading to the diagnosis of Rickettsia massiliae infection.

Emerg Infect DisSep 1, 2026Read case
Case ReportInfectious Diseases

Pulmonary Coccidioidomycosis Linked to Shipping Containers, Taiwan, 2025.

A shipping container yard worker from Taiwan contracted laboratory-confirmed pulmonary coccidioidomycosis. He reported no travel history to endemic regions.

Emerg Infect DisSep 1, 2026Read case

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