Recurrent severe cutaneous reaction to fluoroquinolones and rifampicin in a human immunodeficiency virus-positive patient with disseminated tuberculosis: A rare case report.

Indian J PharmacolSep 2, 2026 (epub)
Case ReportInfectious DiseasesAllergy & Immunology

Divya Chamariya, Taru Garg, Hitesh Verma et al.

✦ AI-curated · Sources linked

Case in brief

A 47-year-old male with HIV and disseminated tuberculosis experienced recurrent maculopapular eruptions with mucosal involvement after exposure to multiple medications, including fluoroquinolones and rifampicin. Drug rechallenge confirmed these agents as culprits. The patient was effectively treated with systemic corticosteroids, intravenous immunoglobulin, and a careful reintroduction of non-culprit anti-tubercular drugs.

Diagnostic / clinical pearl

Clinicians should be cautious when reintroducing fluoroquinolones and rifampicin in immunocompromised patients, as they may provoke severe cutaneous reactions.

Source

PubMed · PMID 42683992

Published in Indian J Pharmacol. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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