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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

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FeaturedClinical ResearchObstetrics & Gynecology

Effects of intradermal lymphocyte therapy in patients with recurrent pregnancy loss: secondary analysis of a randomized controlled trial investigating purinergic signaling, inflammation, and cellular energy status.

Mol Biol RepNov 6, 2026Open access

This secondary analysis of a randomized controlled trial examined low-dose intradermal lymphocyte therapy (ILT) in 100 patients with recurrent pregnancy loss (RPL), comparing 50 treated patients with 50 receiving…

Why it matters

The findings connect a clinical outcome signal with changes in inflammatory markers, purinergic signaling, and cellular energy status in RPL.

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Also worth knowing

Clinical ResearchAllergy & Immunology

Pathophysiology Education Using a Pamphlet Among Early School-Age Children With Food Allergies: An Exploratory Pilot Controlled Study.

This non-randomized exploratory pilot controlled study assessed whether individual instruction alongside a pamphlet improved understanding of food allergy pathophysiology in 46 children in grades 1–3 undergoing oral…

Jpn J Nurs SciNov 7, 2026Read summary
Clinical ResearchDermatology

Five-year outcomes of the STOP-AD randomised controlled trial: Long-term effects of early emollient therapy in high-risk infants.

This blinded, single-centre, randomised controlled trial follow-up assessed whether brief neonatal emollient use was associated with lasting effects on atopic dermatitis (AD) in term infants at high risk of AD.

Pediatr Allergy ImmunolNov 1, 2026Read summary
Clinical ResearchInternal Medicine (General)

Fucoidan as an anti-inflammatory and immunomodulatory agent in humans: a systematic review of clinical evidence and translational potential.

This systematic review assessed human interventional studies of fucoidan supplementation for inflammatory, immune, metabolic, and tumour-related outcomes.

Food FunctNov 2, 2026Read summary
Case ReportAllergy & Immunology

Sirolimus-induced improvement of immune dysregulation associated hepatosplenomegaly in common variable immunodeficiency: a case-based review.

A 50-year-old woman with common variable immunodeficiency (CVID), treated with regular intravenous immunoglobulin replacement, developed progressive hepatosplenomegaly, cytopenias, abdominal enlargement, dyspnea…

Rheumatol IntNov 5, 2026Read case
Case ReportHematology

A case report of ultra-rare SMARCD2 deficiency and review of the literature.

The report describes a patient with congenital neutropenia due to specific granule deficiency type 2, a syndromic autosomal recessive disorder associated with loss-of-function variants in SMARCD2.

Immunol ResNov 5, 2026Read case
Case ReportMedical GeneticsOpen access

"Fatal venous thromboembolism and divergent phenotypes in DOCK8 deficiency: a three-sibling case series".

Three siblings with genetically confirmed DOCK8 deficiency had early-onset atopic dermatitis, recurrent respiratory infections, and failure to thrive. All developed bronchiectasis and severe viral infections.

Immunol ResNov 3, 2026Read case
Case ReportAllergy & Immunology

Peanut Allergy and the Basophil Activation Test in the Military Healthcare System: A Case Series of Monozygotic Twins.

Two adolescent monozygotic twins in a military family had longstanding peanut-allergy labels based on positive routine allergy tests.

Mil MedNov 1, 2026Read case
Case ReportAllergy & Immunology

Treatment-refractory chronic urticaria with neutrophilia and elevated inflammatory markers.

A 38-year-old man had long-standing chronic urticaria that persisted despite standard guideline-directed treatment. Persistent neutrophilia and elevated inflammatory markers raised concern that the presentation might…

Allergy Asthma ProcOct 30, 2026Read case
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