Implementation, adoption and impact of clinical decision support system for antibiotic prescribing in primary care: a systematic review.

J Antimicrob ChemotherSep 1, 2026
Clinical ResearchInfectious DiseasesFamily MedicineOpen access

Racha Ibrahim, Claire Durand, Monsey Macleod et al.

✦ AI-curated · Sources linked

In 30 seconds

This systematic review evaluated the implementation and impact of clinical decision support systems (CDSS) for antibiotic prescribing in primary care, analyzing 40 studies. The review found that CDSS can lead to reduced overall antibiotic prescribing, with 17 out of 32 studies reporting this outcome. Most studies were multicentric and conducted in high-income countries.

Key findings

  • CDSS were integrated into electronic health records in 24 studies (60%).
  • 17 out of 32 studies reported reduced overall antibiotic prescribing.
  • Adoption of CDSS was highly variable, with only five studies using them in more than half of consultations.
  • Barriers to CDSS use included alert fatigue and concerns about patient-doctor trust.

Why it matters

Understanding the effectiveness and challenges of CDSS in antibiotic prescribing can help clinicians navigate the complexities of implementing these systems, ultimately aiming to improve patient care and combat antibiotic resistance.

Source

PubMed · PMID 42678035Free full text on PubMed Central

Published in J Antimicrob Chemother. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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