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119 articles
November 202624
Exploring the Association Between Cannabis Use and Male Reproductive Parameters: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined associations between cannabis use and male reproductive parameters. It included 18 studies reporting sperm outcomes (5,766 patients; 6,231 samples) and hormonal outcomes…
Effects of Polyphenols on Gut Health and Inflammation in Overweight and Obese Populations: A Systematic Review and Meta-analysis of Dose, Duration, and Food Matrix.
This systematic review and meta-analysis assessed polyphenol interventions and gut microbiota and inflammatory biomarkers in people with overweight or obesity, drawing on 32 randomized controlled trials.
2025 National Guidelines on the Mediterranean Diet: Executive Summary of a Joint Report by Italian Scientific Societies and the National Institute of Health Task Force on Clinical Practice Guidelines.
This systematic review and practice guideline, developed by a multidisciplinary panel using NUTRIGRADE, assessed Mediterranean diet evidence across nine health domains and one economic domain.
Effects of Vitamin D Supplementation in Combination With Exercise Training on Body Composition and Muscular Strength in Adults: A Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.
This systematic review and dose-response meta-analysis of randomized controlled trials assessed whether vitamin D supplementation added to exercise improves body composition or muscular strength compared with exercise…
Association Between Vitamin D Status and Nocturnal Lower Urinary Tract Symptoms: A Pooled Analysis.
This systematic review and meta-analysis assessed associations between vitamin D status or intake and nocturnal lower urinary tract symptoms (nLUTS), drawing on 17 studies: 5 randomised trials, 2 cohort studies, 4…
The Role of Diet and Physical Activity in Gut Microbiota Modulation in Type 2 Diabetes Management: A Systematic Review of Clinical Trials.
This systematic review assessed clinical trials of dietary and physical activity interventions and gut microbiota in adults with type 2 diabetes or prediabetes.
Regimens of vitamin D supplementation for women during pregnancy.
This updated Cochrane systematic review and meta-analysis assessed randomised trials of vitamin D regimens during pregnancy in women without pre-existing conditions or multiple pregnancies.
Whole-grain consumption and cardiometabolic risk: a meta-analysis of randomized trials.
This meta-analysis of randomized trials assessed how whole-grain intake affects cardiometabolic risk factors. It included 87 trials (101 publications) and estimated effects per 48 g/day increment in whole grains (dry…
Cardiovascular outcomes of glucagon-like peptide-1 receptor agonists: A systematic review.
This systematic review evaluated 12 cardiovascular outcome-based randomised controlled trials of GLP-1 receptor agonists (GLP1RAs): 10 in people with type 2 diabetes (T2D), one in people with overweight or obesity and…
Sex differences in cardiovascular-kidney-metabolic syndrome: the FINE-HEART pooled analysis.
This prespecified pooled analysis combined participant-level data from three trials involving people with chronic kidney disease and type 2 diabetes or heart failure with mildly reduced or preserved ejection fraction.
Machine Learning Models for Glycemic Prediction in Type 1 and Type 2 Diabetes: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed machine-learning models predicting glucose values or glycemic events in people with type 1, type 2, mixed, or unclear diabetes.
Adrenal ganglioneuroma in an adolescent presenting as an incidentaloma: Imaging-pathology correlation and diagnostic challenges: A case report.
A previously healthy 16-year-old male had a right adrenal mass discovered incidentally on CT after a bicycle accident. CT and MRI showed a well-circumscribed lesion with progressive enhancement and no washout or…
Allan-Herndon-Dudley syndrome associated with SLC16A2 c.1384G>A (p.Gly462Arg): A family case report with retrospective molecular diagnosis in a deceased sibling.
A boy evaluated at 4.3 years had profound developmental delay, abnormal tone, dystonia, muscle atrophy, contractures, and bilateral cryptorchidism.
Time- and posture-specific management of severe supine hypertension and neurogenic orthostatic hypotension in diabetic autonomic neuropathy: A case report.
A 63-year-old man with insulin-treated type 2 diabetes and hypertension developed worsening orthostatic dizziness and recurrent syncope after antihypertensive intensification, including a rib fracture and loss of…
Oral Acarbose Inhibits Baseline Salivary Amylase and Blunts Early Postprandial Glycemia: Randomized Cross-Over Study.
This single-blinded, placebo-controlled randomized cross-over trial examined whether oral acarbose inhibition of salivary α-amylase affects postprandial blood glucose in 15 young, healthy women.
Effects of vitamin D supplementation on vitamin D status and physical performance in football players: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed controlled intervention studies of vitamin D supplementation in association football and futsal players.
Peptides for male sexual dysfunction: a systematic review of emerging evidence.
This PRISMA-guided systematic review assessed human studies of peptide-based therapies for male sexual function, reproductive hormones, and semen parameters.
Vitamin D receptor activator-associated calcium-alkali syndrome-like phenotype without calcium supplementation: a case series of seven patients.
A retrospective series identified seven elderly women receiving vitamin D receptor activators who developed hypercalcemia, bicarbonate of at least 26 mmol/L, and acute kidney injury, meeting the study’s operational…
Erdheim-Chester disease: a diagnostic dilemma - a report of four cases.
Four adults aged 27–40 years presented with neurological Erdheim-Chester disease (ECD), with manifestations including cerebellar ataxia, dysarthria, tremor, visual deterioration, and headache.
Plozasiran for Severe Hypertriglyceridemia and Risk of Pancreatitis.
Two double-blind, placebo-controlled randomized trials evaluated plozasiran in 757 adults with severe hypertriglyceridemia.
Targeting hormone conversion through dietary fiber improves polyendocrine metabolic ovarian syndrome.
This randomized controlled clinical trial examined a combination of inulin, resistant starch, and β-glucan in patients with polyendocrine metabolic ovarian syndrome (PMOS).
Sequential therapy with anlotinib and radioiodine for distant metastatic differentiated thyroid cancer: a phase II clinical trial.
This prospective, single-arm phase II trial evaluated sequential anlotinib and radioiodine (RAI) in patients with measurable distant metastatic differentiated thyroid cancer (DTC).
Effect of Kunxian capsule, a novel Tripterygium wilfordii preparation, on reducing proteinuria and slowing renal function decline in diabetic kidney disease: a 48-week randomized controlled trial.
This 48-week randomized controlled trial assigned 80 patients with diabetic kidney disease to irbesartan-based standard therapy with or without adjunctive Kunxian capsule.
Effects of the integrated care on healthcare utilization and costs among patients with diabetes and depression: a cluster-randomized controlled trial.
This cluster-randomized controlled trial in community health centers in China assessed whether Community-based Integrated Care for Patients with Diabetes and Depression affected healthcare use and costs.
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