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1602 articles

November 202616

Clinical ResearchGeriatrics

Systematic Review of Smart Home Assistive Technology Devices for Supporting People With Dementia Living in Their Homes.

This systematic review and meta-analysis assessed smart home and wearable assistive technologies for people with dementia living at home or in supported accommodation.

Int J Geriatr PsychiatryNov 1, 2026Read summary
Clinical ResearchEndocrinology

Adults With Type 1 Diabetes Are Less Physically Active Than Adults Without Diabetes: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis compared physical activity and sedentary behaviour in adults with type 1 diabetes and adults without diabetes.

Diabetes Metab Res RevNov 1, 2026Read summary
Case ReportPediatrics

Pediatric Liver Transplantation Following Donation After Circulatory Death Using Normothermic Regional Perfusion: A Novel Application.

A 15-year-old girl with fulminant hepatic failure after acetaminophen overdose underwent liver transplantation using a donation-after-circulatory-death graft recovered with thoracoabdominal normothermic regional…

Pediatr TransplantNov 1, 2026Read case
Case ReportAnesthesiologyOpen access

Pump-Predicted Ciprofol Ce50 for Suppressing the Cardiovascular Response to Tracheal Intubation During Fixed Sufentanil-Esketamine Induction: An Age-Stratified Dixon Up-and-Down Study.

To estimate the ciprofol pump-predicted effect-site target concentration associated with a 50% probability of suppressing the cardiovascular response to tracheal intubation (Ce50) during fixed sufentanil-esketamine…

Drug Des Devel TherNov 1, 2026Read case
Case ReportNeurosurgeryOpen access

Single-Stage Bilateral Microsurgical Treatment of Five Complex Unruptured Anterior Circulation Aneurysms Assisted by Rapid Ventricular Pacing: Case Report and Literature Review.

A 54-year-old woman with untreated hypertension and active smoking presented with a pupil-involving left oculomotor nerve palsy.

Int Med Case Rep JNov 1, 2026Read case
Clinical ResearchGastroenterology

Compositional, Spatial and Functional Changes Occur Within Bacteria Associated With Precancerous Colonic Lesions: A Systematic Review.

This systematic review examined human studies comparing gut microbiota in people with colorectal polyps and healthy controls defined by normal colonoscopy.

APMISNov 1, 2026Read summary
Clinical ResearchPediatrics

Diagnosis and Management of Achalasia in Children, BSPGHAN and BAPS Consensus Statement.

This consensus statement addresses diagnosis and management of achalasia in children, for whom pediatric-specific guidelines were lacking.

Neurogastroenterol MotilNov 1, 2026Read summary
Clinical ResearchOncology (Medical)

Immune Checkpoint Inhibitor Rechallenge After Immune-Related Adverse Events: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis pooled observational cohort evidence on restarting immune checkpoint inhibitors (ICIs) after treatment interruption for an immune-related adverse event (irAE).

Cancer MedNov 1, 2026Read summary
Clinical ResearchNeurology

Serum Insulin-Like Growth Factor-1 (IGF-1) in Parkinson's Disease: A Systematic Review and Meta-Analysis.

This systematic review and random-effects meta-analysis examined observational studies comparing serum IGF-1 in people with Parkinson’s disease (PD) and healthy controls, and studies of associations with PD symptoms.

Brain BehavNov 1, 2026Read summary
Clinical ResearchOncology (Medical)

Paxalisib with Trastuzumab for HER2-Positive Metastatic Breast Cancer with Active Brain Metastases: A Phase II Trial with Integrated Plasma and CSF ctDNA Analyses.

This phase II trial evaluated brain-penetrant paxalisib plus trastuzumab in patients with active or progressive HER2-positive breast cancer brain metastases, including heavily pretreated patients; leptomeningeal disease…

Cancer Res CommunNov 1, 2026Read summary
Clinical ResearchOncology (Medical)

Streptozotocin-based chemotherapy in advanced PanNETs: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed objective response and progression-free survival with streptozotocin (STZ)-containing chemotherapy in advanced pancreatic neuroendocrine tumours.

Endocr Relat CancerNov 1, 2026Read summary
Clinical ResearchCardiology

Home Blood Pressure-Guided Lifestyle Intervention for Elevated Blood Pressure Detected at Workplace Health Checkups: A Randomized Pilot Trial.

This randomized pilot trial evaluated home blood pressure (BP) monitoring as part of lifestyle management for elevated BP detected at workplace health checkups.

J Clin Hypertens (Greenwich)Nov 1, 2026Read summary
Clinical ResearchPathology (Anatomic & Clinical)

Cellular and Histopathological Hallmarks of Acute and Chronic Rejection in Vascular Composite Allografts: A Systematic Review.

This systematic review synthesized human studies describing cellular, immunophenotypic, and histopathological features of acute and chronic rejection in vascular composite allografts (VCAs).

Clin TransplantNov 1, 2026Read summary
Clinical ResearchCardiology

Impact of Aspirin Use on Mortality and Cardiac Allograft Vasculopathy After Heart Transplantation: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis examined whether aspirin use was associated with mortality and cardiac allograft vasculopathy (CAV)-related outcomes in heart transplant recipients.

Clin TransplantNov 1, 2026Read summary
Clinical ResearchGeriatrics

Effects of Integrated Multicomponent Care on Older Adults With Frailty or Pre-Frailty: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed integrated multicomponent care (IMC) for older adults with frailty or pre-frailty, including evidence from 20 randomised and quasi-experimental studies.

Int J Older People NursNov 1, 2026Read summary
Clinical ResearchEndocrinology

Supraclavicular thermography does not isolate a brown adipose tissue signal during room temperature β-adrenergic stimulation in adults.

Two randomized, single-blind, placebo-controlled crossover trials studied thermogenic responses to β-adrenergic stimulation in healthy adults.

Physiol RepNov 1, 2026Read summary

October 20268

Clinical ResearchOncology (Medical)

Local ablative treatment for oligoprogression during immunotherapy in metastatic non-small-cell lung cancer: a systematic review and meta-analysis.

This PRISMA-compliant systematic review and meta-analysis assessed local ablative treatment (LAT), with continuation of the same immune checkpoint inhibitor, for oligoprogressive or oligo-resistant metastatic NSCLC…

OncoimmunologyOct 31, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Evaluation of surgical outcomes and costs during the learning curve in robotic gynecologic surgery: a systematic review and meta-analysis.

This systematic review and meta-analysis examined whether surgical outcomes and costs differed between earlier and later cases of the same robotic gynecologic procedures.

J Robot SurgOct 31, 2026Read summary
Clinical ResearchNeurologyOpen access

Pharmacological Interventions for Neurological Manifestations of Ataxia-Telangiectasia: An Updated Systematic Review and Meta-analysis of Randomized Controlled Trials.

This updated systematic review and meta-analysis examined randomized trials of pharmacological treatments for neurological manifestations of ataxia-telangiectasia in children and adults.

CerebellumOct 31, 2026Read summary
Case ReportNeurologyOpen access

COQ8A-Associated Ataxia in a Colombian Patient Presenting with Bilateral Ptosis and Response to CoQ10 Supplementation.

A 67-year-old woman with consanguineous parents had gait instability and exercise intolerance from age 10, progressing very slowly.

CerebellumOct 31, 2026Read case
Clinical ResearchOphthalmologyOpen access

Toxoplasmosis-associated optic neuropathies: a systematic review and meta-analysis of clinical characteristics, diagnosis, and outcomes.

This systematic review and meta-analysis examined optic neuropathies associated with ocular toxoplasmosis (OT), combining observational studies and case reports.

Int OphthalmolOct 31, 2026Read summary
Clinical ResearchOtolaryngology (ENT)Open access

Efficiency of different approaches in teaching tracheal suctioning procedure to caregivers of tracheostomy patients: randomized controlled study.

This randomized controlled study compared simulation-based and mobile application training with routine bedside instruction for primary caregivers of people with tracheostomies, including patients with head and neck…

Support Care CancerOct 31, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Early functional deterioration during first-line ICI-based therapy in advanced NSCLC: implications for supportive care.

This secondary exploratory analysis of prospectively collected data from a randomized pulmonary rehabilitation trial assessed early functional change in 42 people receiving first-line immune checkpoint inhibitor–based…

Support Care CancerOct 31, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Glucose and insulin responses to monk fruit-based sweetener formulations and their effects on appetite, liking and wanting, and energy intake (GREEN): a randomized double-blind, crossover study.

This randomized, double-blind, crossover study compared three monk fruit-based sweetener formulations (MF1–MF3) with sucrose and sucralose in 30 healthy adults.

Eur J NutrOct 31, 2026Read summary

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