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1602 articles
November 202624
Liposomal irinotecan and capecitabine plus bevacizumab as second-line therapy in metastatic colorectal cancer: A multicenter, single-arm study.
This multicenter, single-arm clinical study evaluated liposomal irinotecan, capecitabine, and bevacizumab as second-line therapy in patients with metastatic colorectal cancer progressing after oxaliplatin-based…
Biomarker Modulation by Aspirin and Metformin for Colorectal Cancer Prevention: Results from the ASAMET Randomized Phase II Trial.
The multicenter, double-blind, 2 × 2 factorial phase II ASAMET randomized trial evaluated aspirin, metformin, and their combination for 12 months in patients with resected stage I to III colorectal cancer.
Structural Brain Correlates of Bulimia Nervosa Diagnosis and Symptom Severity: A Coordinated ENIGMA Eating Disorders Working Group Analysis.
This coordinated, international case-control meta-analysis examined structural MRI correlates of bulimia nervosa (BN) diagnosis and symptom severity across 17 cohorts at 13 sites.
Recurrent Cardiac Cephalalgia: A Case Report and Pooled Narrative Review.
An elderly man with multiple cardiovascular risk factors and prior coronary artery disease treated with percutaneous coronary intervention had progressive exertional headaches over several years, without typical cardiac…
Vogt-Koyanagi-Harada (VKH) Syndrome Mimicking Bilateral Optic Neuritis.
A 36-year-old man developed progressive bilateral visual loss over 5 days, with papillitis on fundus examination. Brain MRI and CSF were normal, and serum NMO and MOG testing was negative.
Brain Abscesses as a Complication of Brain Hematomas in Infective Endocarditis: A Rare Case Report.
A previously healthy 26-year-old man with methicillin-sensitive Staphylococcus aureus infective endocarditis had a 24-mm parietal hematoma; angiography showed no aneurysm.
Polyneuropathy, Organomegaly, Endocrinopathy, M-Protein, and Skin Changes (POEMS) Syndrome With Characteristic Muscle Biopsy Findings and Without M-Protein.
A 63-year-old woman referred with presumed CIDP had not responded to IVIG or steroids. Her presentation included marked weight loss, papilledema, skin changes, thrombocytosis, thromboembolisms, hemi-diaphragmatic…
Anti-Contactin-1 Nodopathy Presenting With Dysphagia and Nephrotic Syndrome: Remarkable Neurological and Renal Recovery Following Early B-Cell-Targeted Therapy.
A 77-year-old man with diabetes and pre-existing heavy proteinuria developed rapidly progressive distal numbness, weakness, sensory ataxia, mild dysphagia, and functional decline.
Anatomy-specific Performance of CTA-based AI for Anterior Circulation Occlusion: Systematic Review and Meta-analysis.
This prospectively registered systematic review and diagnostic meta-analysis assessed CTA-based artificial intelligence for detecting anterior-circulation occlusions, using 31 reports involving 15 708 patients.
Assessing the reproductive lifespan of female cancer survivors using AMH: a meta-synthesis of longitudinal studies.
This systematic review and meta-synthesis quantified AMH changes after cancer treatment in female survivors and compared longer-term trajectories with age-matched controls.
Clinical outcomes of Day-7 blastocysts: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis compared frozen Day-7 blastocyst transfers with Day-5 and Day-6 transfers.
Clinical outcomes and euploidy rates of embryos derived from zygotes with nonpronuclear (0PN) and monopronuclear (1PN) in IVF or ICSI cycles: a systematic review and meta-analysis.
This systematic review and meta-analysis compared euploidy and clinical outcomes for embryos derived from 0PN or 1PN zygotes with those from normally fertilized 2PN zygotes in IVF/ICSI cycles.
The Effect of Virtual Reality on Anxiety and Vital Signs in Patients Undergoing Total Knee Replacement Surgery: A Randomized Controlled Trial.
This randomized controlled trial evaluated whether intraoperative virtual reality affected anxiety and vital signs in 70 patients undergoing total knee replacement.
The Effect of Game-based Mobile Application in Learning Postpartum Hemorrhage Management for Midwifery Students.
This two-phase randomized controlled study developed and evaluated a game-based mobile application for postpartum hemorrhage (PPH) management education.
European Guidelines on Multidisciplinary Management of Obstructed Defecation Syndrome-ESCP, UEG, ESGAR, EAGEN, ESGENA, ESNM and ESPCG.
These European multidisciplinary practice guidelines address diagnosis and management of obstructed defecation syndrome (ODS).
LEgal Guidance for Cancer Patients and CAREgivers (LEGACY CARE): A Pilot Clinical Trial.
This single-arm pilot clinical trial evaluated the feasibility and acceptability of proactive legal care for patient-caregiver dyads affected by advanced-stage colorectal cancer.
Emergency management of obturator hernıa in elderly patients: A case series and surgical strategy.
Three elderly, cachectic women presented with symptoms and signs of mechanical intestinal obstruction. CT imaging identified obturator hernias, and all underwent emergency surgery.
Severe acute gastric volvulus: A case report with perforation and extra-gastric ischemic findings.
A 36-year-old man presented with sudden abdominal distension and respiratory distress, with severe hemodynamic instability and an acute abdomen. Imaging showed intraperitoneal free air, leading to emergency laparotomy.
A rare injury combination: Hawkins type I talar neck fracture, Jones fracture, and calcaneal avulsion fracture accompanying a bimalleolar ankle fracture.
A patient with a bimalleolar ankle fracture also had a Jones fracture, a Hawkins type I talar neck fracture, and a calcaneal avulsion fracture.
Effects of CT-guided Radiofrequency Versus Microwave Ablation on Pulmonary Function in Individuals with Pulmonary Tumors: A Prospective Multicenter Randomized Trial.
This prospective, multicenter randomized trial compared short-term pulmonary function after CT-guided radiofrequency ablation (RFA) or microwave ablation (MWA) in 138 participants with pulmonary tumors.
Late Traumatic Avulsion of a Femtosecond LASIK Flap Following a Direct Corneal Injury: A Case Report.
A 34-year-old woman developed pain and reduced vision after a pet bird injured her left cornea, 10 months after uncomplicated femtosecond LASIK.
In-the-Bag Stability of a New Hydrophilic Acrylic Toric Intraocular Lens.
This single-centre, prospective interventional clinical trial assessed in-the-bag stability of the RayOne EMV toric intraocular lens in 119 eyes of 79 patients with age-related cataract over 6 months.
Anterior Chamber Depth Changes: After Phacoemulsification in Eyes With Pseudoexfoliation Syndrome Versus Control Eyes: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis compared anterior chamber depth (ACD) before and after phacoemulsification in eyes with pseudoexfoliation syndrome (PEX) and control eyes.
The Impact of Outcome Measures for Responder Analyses in Placebo-Controlled Trials of Pharmacological Treatments for Neuropathic Pain.
This meta-analysis examined how dichotomous responder definitions affect estimated treatment effects in placebo-controlled pharmacological trials for neuropathic pain.
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